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Drug-induced systemic lupus erythematosus after 8 years of treatment with carbamazepine

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Abstract

This is the report of a late-onset carbamazepine-induced systemic lupus erythematosus in a 34- year-old patient who had been treated with daily carbamazepine for 8 years because of complex partial seizures. When carbamazepine was discontinued,␣symptoms rapidly improved and antinuclear antibodies disappeared. So far, few cases have been reported of carbamazepine-induced lupus erythematosus within months after the start of treatment. This is the first case report about carbamazepine-induced systemic lupus erythematosus with serological confirmation after years of treatment without side effects.

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Received: 3 November 1997 / Accepted in revised form: 7 January 1998

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Toepfer, M., Sitter, T., Lochmüller, H. et al. Drug-induced systemic lupus erythematosus after 8 years of treatment with carbamazepine. E J Clin Pharmacol 54, 193–194 (1998). https://doi.org/10.1007/s002280050444

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  • DOI: https://doi.org/10.1007/s002280050444

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