An unusual case of fatal hypothermia involving topical diphenhydramine | | |
Quantification of SHR0302 in human plasma by UPLC–MS/MS and application to a pharmacokinetic study | | |
New Modalities | | 2022 |
Platform and Instrument Considerations in Bioanalytical Testing | | 2022 |
Alternative sample injection loop for the Dionex TM UltiMate TM 3000 analytical autosampler | | 2022 |
Simultaneous quantification of urinary tobacco and marijuana metabolites using solid-supported liquid-liquid extraction coupled with liquid chromatography tandem mass spectrometry | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2022 |
Pharmacokinetic Drug–Drug Interaction Studies Between Trilaciclib and Midazolam, Metformin, Rifampin, Itraconazole, and Topotecan in Healthy Volunteers and Patients with Extensive-Stage Small-Cell Lung Cancer | Clinical Drug Investigation | |
Population pharmacokinetic modelling of imatinib in healthy subjects receiving a single dose of 400 mg | Cancer Chemotherapy and Pharmacology | |
Immunoassay-Compatible Inactivation of SARS-CoV-2 in Plasma Samples for Enhanced Handling Safety | ACS Omega | |
Development, validation, and clinical application of a rapid UPLC–MS/MS method for detection of colchicine in human whole blood and urine | Biomedical Chromatography | |
Quantitative analysis of specific androgens in serum and urine samples from male, pre, and postmenopausal subjects using LC-MRM-MS | Steroids | 2022 |
Effect of concomitant oral administration of ethanol on the pharmacokinetics of nicardipine in rats | Biomedical Chromatography | |
Stereoselective interaction of tolvaptan with amiodarone under racemic metabolic impact by CYP3A5 genotypes in heart failure patients | European Journal of Clinical Pharmacology | |
Effects of itraconazole and rifampicin on the pharmacokinetics and safety of youkenafil, a novel phosphodiesterase type 5 inhibitor, in healthy Chinese subjects | European Journal of Pharmaceutical Sciences | 2022 |
High-sensitivity quantification of antisense oligonucleotides for pharmacokinetic characterization. | Bioanalysis | 2022 |
In situ synthesis of monolithic sol-gel polyethylene glycol-based sorbent encapsulated in porous polypropylene microextraction capsules and its application for selective extraction of antifungal and anthelmintic drugs from human urine | Microchemical Journal | 2022 |
Measurement of 7-dehydrocholesterol and cholesterol in hair can be used in the diagnosis of Smith-Lemli-Opitz syndrome. | Journal of Lipid Research | 2022 |
New insights into the phenolic constituents and their relationships with antioxidant capacity during the growth of a commonly consumed Asian vegetable, Brassica rapa var. parachinensis (choy sum) | | 2022 |
Inhibitory effects of fluoxetine and duloxetine on the pharmacokinetics of metoprolol in vivo and in vitro. | Fundamental and Clinical Pharmacology | 2022 |
Effect of Baicalein on the Pharmacokinetics of Cilostazol and Its Two Metabolites in Rat Plasma Using UPLC-MS/MS Method. | Frontiers in Pharmacology | 2022 |
Data_Sheet_1.XLSX | | 2020 |
Development and Validation of an Analytical Method to Quantitate Hydroxycitric Acid, the Key Constituent in Extract, in Rodent Plasma and Fetus. | Analytical Letters | 2022 |
Development and validation of a new liquid chromatography-tandem mass spectrometry assay for the simultaneous quantification of afatinib, dacomitinib, osimertinib, and the active metabolites of osimertinib in human serum. | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2022 |
Simultaneous Determination of Carvedilol, Enalaprilat, and Perindoprilat in Human Plasma Using LC–MS/MS and Its Application to a Pharmacokinetic Pilot Study | Chromatographia | |
Pharmacokinetics of XEN496, a Novel Pediatric Formulation of Ezogabine, Under Fed and Fasted Conditions: A Phase 1 Trial. | Neurology and Therapy | 2022 |
Biological Matrix Supply Chain Shortages: More Matrices Are Now Rare-the Case for Surrogate Matrices. | AAPS Journal | 2022 |
Comparison of three parallelism assessment methods of biomarker quantification by LC-MS/MS: a case study of the bioanalysis of creatinine in human urine samples. | Bioanalysis | 2022 |
Chemical, Analytical and Pharmacokinetic Characterisation of RO7304898, an API Consisting of Two Rapidly Interconverting Diastereoisomers. | Pharmaceutical Research | 2022 |
HPLC method with post-column derivatization for the analysis of endogenous histidine in human saliva validated using the total-error concept. | Amino Acids | 2022 |
Combination of fabric phase sorptive extraction with UHPLC-ESI-MS/MS for the determination of adamantine analogues in human urine | Microchemical Journal | 2022 |
Methods paper: Performance characteristics of novel assays for circulating levels of proglucagon-derived peptides and validation in a placebo controlled cross-over randomized clinical trial. | Metabolism: Clinical and Experimental | 2022 |
Review of characteristics and analytical methods for determination of indomethacin | Reviews in Analytical Chemistry | 2022 |
A robust, accurate, sensitive LC-MS/MS method to measure indoxyl sulfate, validated for plasma and kidney cells. | Biomedical Chromatography | 2022 |
Population Pharmacokinetic Modeling and Simulation of TQ-B3101 to Inform Dosing in Pediatric Patients With Solid Tumors. | Frontiers in Pharmacology | 2021 |
Preliminary results using a kit to measure tamoxifen and metabolites concentrations in capillary blood samples from women with breast cancer. | Scientific Reports | 2022 |
Reductions in biomarkers of exposure to selected harmful and potentially harmful constituents following exclusive and partial switching from combustible cigarettes to myblu electronic nicotine delivery systems (ENDS) | Internal and Emergency Medicine | 2021 |
A highly sensitive and rapid LC-MS/MS method for quantification of bexarotene in mouse plasma and brain tissue: Application to mice pharmacokinetic study | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2021 |
Direct quantitation of free, encapsulated, total doxorubicin and doxorubicinol in stabilized frozen human plasma to support a BE study of liposomal doxorubicin | Journal of Pharmaceutical and Biomedical Analysis | 2020 |
Validation Strategy as a Part of the European Gas Network Protection | | |
Semi-Mechanistic Modeling of HY-021068 Based on Irreversible Inhibition of Thromboxane Synthetase | Frontiers in Pharmacology | 2020 |
Development and Validation of Pomalidomide Determination in Human Plasma by HPLC-MS/MS Method | Drug Development and Registration | 2020 |
A multicenter analytical performance evaluation of a multiplexed immunoarray for the simultaneous measurement of biomarkers of micronutrient deficiency, inflammation and malarial antigenemia | PLoS ONE | 2021 |
Concepts and Software Package for Efficient Quality Control in Targeted Metabolomics Studies – MeTaQuaC | | |
A sensitive LC-MS/MS method for simultaneous quantification of ulotaront and its N-desmethyl metabolite in human plasma and application to a clinical study | Journal of Pharmaceutical and Biomedical Analysis | 2022 |
Pharmacokinetic Studies of Multiple Active Components in Rat Plasma Using LC-MS/MS after Oral Administration of Shaoyao-Gancao-Fuzi Decoction | Revista Brasileira De Farmacognosia | 2020 |
Investigation of the Inhibitory Effect of Simvastatin on the Metabolism of Lidocaine Both in vitro and in vivo | Drug Design, Development and Therapy | 2020 |
Development and Validation of Atazanavir and Ritonavir Determination in Human Plasma by HPLC-MS Method | Drug Development and Registration | 2020 |
Quantification of the anti-murine PD-1 monoclonal antibody RMP1-14 in BALB/c mouse plasma by liquid chromatography-tandem mass spectrometry and application to a pharmacokinetic study | Analytical and Bioanalytical Chemistry | 2020 |
Development and Validation of HPLC-MS/MS Method for Busereline Quantitation in Animal Blood Plasma | Drug Development and Registration | 2019 |
Development and Validation of Tadalafil Determination in Human Plasma by HPLC-MS Method | Drug Development and Registration | 2019 |
A new dried blood spot LC-MS/MS method for therapeutic drug monitoring of palbociclib, ribociclib, and letrozole in patients with cancer | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2021 |
Potential application of measuring serum infliximab levels in rheumatoid arthritis management: A retrospective study based on KURAMA cohort data | PLoS ONE | 2021 |
Crime Scene Investigation: Simulated Post-mortem LC–MS/MS Analysis of Cocaine and Cocaine Metabolites in Synthetic Human Serum | Journal of Chemical Education | |
Distribution evaluation of tacrolimus in the ascitic fluid of liver transplant recipients with liver cirrhosis by a sensitive ultra-performance liquid chromatography-tandem mass spectrometry method | Journal of Separation Science | 2021 |
A new grey relational analysis application in analytical chemistry: Natural deep eutectic solvent as a green extractant for HPLC determination of lamotrigine in plasma | Microchemical Journal | 2022 |
Exploiting the capsule phase microextraction features in bioanalysis: Extraction of ibuprofen from urine samples | Microchemical Journal | 2022 |
A New Cost-Efficient Technique for Analysis of Nectar Sugars and Dihydroxyacetone in Australian Leptospermum Using Liquid Chromatography–Tandem Mass Spectrometry | ACS Food Science & Technology | |
Rapid sensitive bioscreening of remdesivir in COVID-19 medication: Selective drug determination in the presence of six co-administered therapeutics | Reviews in Analytical Chemistry | 2021 |
Development and Validation of Valganciclovir and its Active Metabolite Ganciclovir Determination in Human Plasma by HPLC-UV Method | Drug Development and Registration | 2020 |
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) method development for screening of potential tamoxifen-drug/herb interaction via in vitro cytochrome P450 inhibition assay | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
Influence of two-period cross-over design on the bioequivalence study of gefitinib tablets in beagle dogs | European Journal of Pharmaceutical Sciences | 2021 |
Determination of gluten immunogenic peptides for the management of the treatment adherence of celiac disease: A systematic review | World Journal of Gastroenterology | 2021 |
A New Electrochemiluminescence-Based Multiplex Assay for the Assessment of Human Antibody Responses to Bordetella pertussis Vaccines | Infectious Diseases and Therapy | 2021 |
Characterization by HPLC of p-Hydroxybenzyl Alcohol Biotransformation to Gastrodin In Vivo | Natural Product Communications | 2021 |
Influence of and Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Bisoprolol in Hypertensive Chinese Patients | Frontiers in Medicine | 2021 |
Neuropharmacokinetic visualization of regional and subregional unbound antipsychotic drug transport across the blood-brain barrier | Molecular Psychiatry | 2021 |
Blood-Placental Barrier Transfers and Pharmacokinetics of Unbound Morphine in Pregnant Rats with Multiple Microdialysis Systems | ACS Pharmacology and Translational Science | 2021 |
How the COVID-19 pandemic is changing clinical trial conduct and driving innovation in bioanalysis | Bioanalysis | 2021 |
Developing urinary pyrrole-amino acid adducts as non-invasive biomarkers for identifying pyrrolizidine alkaloids-induced liver injury in human | Archives of Toxicology | 2021 |
Simultaneous quantification of dexamethasone and 6β-hydroxydexamethasone in rabbit plasma, aqueous and vitreous humor, and retina by UHPLC-MS/MS | Bioanalysis | 2021 |
Infectious titer determination of lentiviral vectors using a temporal immunological real-time imaging approach | PLoS ONE | 2021 |
Simultaneous LC-MS/MS bioanalysis of alkaloids, terpenoids, and flavonoids in rat plasma through salting-out-assisted liquid-liquid extraction after oral administration of extract from Tetradium ruticarpum and Glycyrrhiza uralensis: a sample preparation strategy to broaden analyte coverage of herbal medicines | Analytical and Bioanalytical Chemistry | 2021 |
Reversed lipid micellar hollow-fiber liquid-phase microextraction of rotigotine in rat plasma | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2021 |
Effect of Oral Ranitidine on Urinary Excretion of N-Nitrosodimethylamine (NDMA): A Randomized Clinical Trial | JAMA - Journal of the American Medical Association | 2021 |
Propensity score matching evaluation of psychological stress and hair cortisol among people living with HIV in China | Scientific Reports | 2021 |
Preclinical Pharmacokinetics and Pharmacodynamics of Coptidis Preparation in Combination with Lovastatin in High-Fat Diet-Induced Hyperlipidemic Rats | ACS Omega | 2021 |
Stability study of a compounded oral solution of nicardipine for the treatment of hypertension in children | European Journal of Pharmaceutical Sciences | 2021 |
Critical reagents: evolution of WRIB recommendations on critical reagents | Bioanalysis | 2021 |
Oral bioavailability and pharmacokinetics of esculetin following intravenous and oral administration in rats | Xenobiotica | 2021 |
Development of a LC-MS/MS method to measure serum 3-sulfate and 3-glucuronide 25-hydroxyvitamin D3 metabolites; comparisons to unconjugated 25OHD in pregnancy and polycystic ovary syndrome | Steroids | 2021 |
Adolescent fluoxetine treatment mediates a persistent anxiety-like outcome in female C57BL/6 mice that is ameliorated by fluoxetine re-exposure in adulthood | Scientific Reports | 2021 |
LC-MS/MS method for simultaneous quantification of dexamethasone and tobramycin in rabbit ocular biofluids | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2021 |
Pharmacokinetics-based comprehensive strategy to identify multiple effective components in Huangqi decoction against liver fibrosis | Phytomedicine | 2021 |
Objective assessment of alcohol consumption in early pregnancy using phosphatidylethanol: a cross-sectional study | BMC Pregnancy and Childbirth | 2021 |
The Comparison of Plasma and Cerebrospinal Fluid R(-)- and S(+)-Flurbiprofen Concentration After Intravenous Injection of Flurbiprofen Axetil in Human Subjects | Frontiers in Pharmacology | 2021 |
Quantification of Thioguanine in DNA Using Liquid Chromatography-Tandem Mass Spectrometry for Routine Thiopurine Drug Monitoring in Patients With Pediatric Acute Lymphoblastic Leukemia | Annals of Laboratory Medicine | 2021 |
Development of a multi-mycotoxin LC-MS/MS method for the determination of biomarkers in pig urine | Mycotoxin Research | 2021 |
Development and Validation of Valganciclovir and its Active Metabolite Ganciclovir Determination in Human Plasma by HPLC-MS/MS Method | Drug Development and Registration | 2021 |
An UPLC-MS/MS method for quantification of D-pinitol in rat plasma and its application to a pharmacokinetic and bioavailability study | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2021 |
Quantitative selenium speciation in feed by enzymatic probe sonication and ion chromatography-inductively coupled plasma mass spectrometry | Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment | 2021 |
Development of a clinical assay to measure chlorinated tyrosine in hair and tissue samples using a mouse chlorine inhalation exposure model | Analytical and Bioanalytical Chemistry | 2021 |
Pharmacokinetic interaction between dronedarone and ticagrelor following oral administration in rats | Xenobiotica | 2021 |
Validation of a mass spectrometry method to identify and quantify ellagitannins in oak wood and cognac during aging in oak barrels | Food Chemistry | 2021 |
Improved intact peptide and protein quantitation by LC-MS: Battling the deleterious effects of analyte adsorption | Analytical Science Advances | 2021 |
Perspectives on updates, clarifications and controversies in chromatographic assay guidance for bioanalytical method validation from major regulatory agencies and organizations | Biomedical Chromatography | 2021 |
LC-MS/MS quantification of progesterone in ovariectomized miniature swine and its application for preliminary pharmacokinetic study of a novel vaginal sustained release system | Drug Development and Industrial Pharmacy | 2021 |
Determination of levetiracetam in plasma: Comparison of gas chromatography-mass spectrometry technique and Abbot® Architect system | Microchemical Journal | 2021 |
Plasma protein binding, metabolism, reaction phenotyping and toxicokinetic studies of fenarimol after oral and intravenous administration in rats | Xenobiotica | 2021 |
Intranasal fosphenytoin: The promise of phosphate esters in nose-to-brain delivery of poorly soluble drugs | International Journal of Pharmaceutics | 2021 |
Method development and validation of dissolution testing for nicotine release from smokeless tobacco products using flow-through cell apparatus and UPLC-PDA | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
WITHDRAWN: Ratio of Morphine and Codeine over Antihistamines in Urine by LC-MS/MS for Determining Opiate Metabolites from Cold Syrups | Forensic Science International | 2020 |
Determination of free clindamycin, flucloxacillin or tedizolid in plasma: Pay attention to physiological conditions when using ultrafiltration | Biomedical Chromatography | 2020 |
Simultaneous quantitation of glycyrrhetic acid and puerarin in plasma using ultra flow liquid chromatography tandem mass spectrometry and application in a pharmacokinetics study in healthy and alcoholic liver injury rats | Biomedical Chromatography | 2020 |
Intestinal Flora Modulates Blood Pressure by Regulating the Synthesis of Intestinal-Derived Corticosterone in High Salt-Induced Hypertension | Circulation Research | 2020 |
Screening and identification of salivary biomarkers for assessing the effects of exogenous testosterone administration on HPG and HPA axes and ECS | Steroids | 2020 |
CalibraCurve: A Tool for Calibration of Targeted MS-Based Measurements | Proteomics | 2020 |
Simultaneous quantification of palbociclib, ribociclib and letrozole in human plasma by a new LC-MS/MS method for clinical application | PLoS ONE | 2020 |
Simple, fast and robust LC-MS/MS method for the simultaneous quantification of canagliflozin, dapagliflozin and empagliflozin in human plasma and urine | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
Population pharmacokinetics of busulfan in Saudi pediatric patients undergoing hematopoietic stem cell transplantation | International Journal of Clinical Pharmacy | 2020 |
Validation of a Bioanalytical Method for the Determination of Synthetic and Natural Cannabinoids (New Psychoactive Substances) in Oral Fluid Samples by Means of HPLC-MS/MS | Frontiers in Chemistry | 2020 |
Interspecies differences on pharmacokinetics of rebamipide following oral administration to rats and dogs | Biopharmaceutics and Drug Disposition | 2020 |
Determination of levofloxacin, ciprofloxacin, moxifloxacin and gemifloxacin in urine and plasma by HPLC-FLD-DAD using pentafluorophenyl core-shell column: Application to drug monitoring | Biomedical Chromatography | 2020 |
Dual-Probe Approach for Mass Spectrometric Quantification of MUC1-Specific Terminal Gal/GalNAc | Analytical Chemistry | 2020 |
UPLC-Tandem Mass Spectrometry for Quantification of Busulfan in Human Plasma: Application to Therapeutic Drug Monitoring | Scientific Reports | 2020 |
Development of a plasma pseudotargeted metabolomics method based on ultra-high-performance liquid chromatography-mass spectrometry | Nature Protocols | 2020 |
A simple, rapid and sensitive high-performance thin-layer chromatographic method for the simultaneous estimation of berberine and 5-fluorouracil in rabbit plasma | Journal of Planar Chromatography - Modern TLC | 2020 |
Pharmacokinetics of bioactive components after oral administration of Bojungikgi-tang in Korean subjects | Journal of Pharmaceutical Investigation | 2020 |
Quantification of Colistin in Plasma by Liquid Chromatography-Tandem Mass Spectrometry: Application to a Pharmacokinetic Study | Scientific Reports | 2020 |
Verification, analytical validation, and clinical validation (V3): the foundation of determining fit-for-purpose for Biometric Monitoring Technologies (BioMeTs) | Npj Digital Medicine | 2020 |
Signal Drift in Liquid Chromatography Tandem Mass Spectrometry and Its Internal Standard Calibration Strategy for Quantitative Analysis | Analytical Chemistry | 2020 |
Simple LC-MS/MS method using core-shell ODS microparticles for the simultaneous quantitation of edoxaban and its major metabolites in human plasma | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
A Pharmacokinetic Study of Methylphenidate Hydrochloride Multilayer Extended-Release Capsules (Aptensio XR) in Preschool-Aged Children with Attention-Deficit/Hyperactivity Disorder | Paediatric Drugs | 2020 |
Population pharmacokinetic analysis of nanoparticle-bound and free camptothecin after administration of NLG207 in adults with advanced solid tumors | Cancer Chemotherapy and Pharmacology | 2020 |
Development and validation of a simple LC-MS/MS method for simultaneous determination of moxifloxacin, levofloxacin, prothionamide, pyrazinamide and ethambutol in human plasma | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
Electromembrane extraction of chlorprothixene, haloperidol and risperidone from whole blood and urine | Journal of Chromatography A | 2020 |
Homogeneous liquid liquid extraction using salt as mass separating agent for the ultra high pressure liquid chromatographic determination of doxorubicin in human urine | Microchemical Journal | 2020 |
Method validation | | 2020 |
A sensitive method for analyzing fluconazole in extremely small volumes of neonatal serum | Journal of Pharmaceutical Health Care and Sciences | 2020 |
A micro salting-out assisted liquid-liquid extraction combined with ultra-high performance liquid chromatography tandem mass spectrometry to determine anandamide and 2-arachidonoylglycerol in rat brain samples | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
Establishing repeatability and ruggedness of chiral separations in micellar electrokinetic chromatography mass spectrometry: Combined use of covalently bonded capillary column and molecular micelles | Journal of Chromatography A | 2020 |
Current Perspectives on Ligand-Binding Assay Practices in the Quantification of Circulating Therapeutic Proteins for Biosimilar Biological Product Development | AAPS Journal | 2019 |
Restricted access macroporous magnetic polyaniline for determination of coumarins in rat plasma | Microchemical Journal | 2020 |
A compartmental approach to isosteviol's disposition in Sprague-Dawley rats | Naunyn-Schmiedeberg's Archives of Pharmacology | 2020 |
Bioanalytical method validation: How much should we do and how should we document? | Analytical and Bioanalytical Chemistry | 2020 |
Antiepileptic Drug Exposure in Infants of Breastfeeding Mothers With Epilepsy | JAMA Neurology | 2020 |
Nanoemulsions and thermosensitive nanoemulgels of phenytoin and fosphenytoin for intranasal administration: Formulation development and in vitro characterization | European Journal of Pharmaceutical Sciences | 2020 |
Development of a liquid chromatography/tandem-mass spectrometry assay for the simultaneous determination of teneligliptin and its active metabolite teneligliptin sulfoxide in human plasma | Biomedical Chromatography | 2020 |
Development and Validation of a New LC-MS/MS Analytical Method for Direct-Acting Antivirals and Its Application in End-Stage Renal Disease Patients | European Journal of Drug Metabolism and Pharmacokinetics | 2020 |
Development and validation of LC-MS/MS method for imatinib and norimatinib monitoring by finger-prick DBS in gastrointestinal stromal tumor patients | PLoS ONE | 2019 |
Determination of anandamide in cerebrospinal fluid samples by disposable pipette extraction and ultra-high performance liquid chromatography tandem mass spectrometry | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2019 |
LC-ESI-MS/MS quantification of carnosine, anserine, and balenine in meat samples | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2019 |