Therapeutic drug monitoring of caffeine and its primary metabolites in plasma using LC–ESI–MS/MS for apnea of prematurity treatment: Evaluation of ultrapure water as a surrogate matrix | | |
Critical Reagents in Bioanalysis | | 2022 |
Validation of a liquid chromatography coupled to tandem mass spectrometry method for simultaneous quantification of tryptophan and 10 key metabolites of the kynurenine pathway in plasma and urine: Application to a cohort of acute kidney injury patients | Clinica Chimica Acta | 2022 |
Noninvasive monitoring of bilirubin photoisomer excretion during phototherapy | Scientific Reports | 2022 |
Bioanalytical methods for the detection of duloxetine and thioctic acid in plasma using ultra performance liquid chromatography with tandem mass spectrometry (UPLC-MS/MS) | Translational and Clinical Pharmacology | 2022 |
Recommendations on qPCR/ddPCR Assay Validation by GCC | Bioanalysis | |
Simultaneous quantification of eight hemoglobin adducts of genotoxic substances by isotope-dilution UHPLC-MS/MS | Analytical and Bioanalytical Chemistry | |
Rapid, simple, and economical LC–MS/MS method for simultaneous determination of ceftazidime and avibactam in human plasma and its application in therapeutic drug monitoring | Journal of Clinical Pharmacy and Therapeutics | |
Analytical validation of a multivariate proteomic serum-based assay for disease activity assessments in multiple sclerosis | | |
Development and validation of a high performance liquid chromatography-MS/MS method for determination of SOMCL-15-290 in a first-in-human study. | Bioanalysis | 2022 |
LC-MS/MS methods for determination of unstable pivmecillinam and mecillinam in acidified human plasma: Application to a pharmacokinetic study. | Journal of Separation Science | 2022 |
Quantification of urinary steroids by supported liquid extraction with GC-MS/MS: Unravelling cyclic fluctuations of steroid profiling in regular menstrual cycle. | Journal of Pharmaceutical and Biomedical Analysis | 2022 |
Determination of free and encapsulated cytarabine and daunorubicin in rat plasma after intravenous administration of liposomal formulation using ultra-high performance liquid chromatography tandem mass spectrometry. | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2022 |
Population pharmacokinetics of intranasal dexmedetomidine in infants and young children. | Anesthesiology | 2022 |
Bedaquiline exposure in pregnancy and breastfeeding in women with rifampicin-resistant tuberculosis. | British Journal of Clinical Pharmacology | 2022 |
Pharmacokinetics and metabolism of penindolone in rat plasma using liquid chromatography-tandem mass spectrometry. | Biomedical Chromatography | 2022 |
Method development and validation for analysis of phenylalanine, 4‐hydroxyphenyllactic acid and 4‐hydroxyphenylpyruvic acid in serum and urine | JIMD Reports | |
Effect of mild or moderate hepatic impairment on the pharmacokinetics of risdiplam. | British Journal of Clinical Pharmacology | 2022 |
Bioanalytical Methods and Strategic Perspectives Addressing the Rising Complexity of Novel Bioconjugates and Delivery Routes for Biotherapeutics. | BioDrugs | 2022 |
Bayesian calibration, process modeling and uncertainty quantification in biotechnology. | PLoS Computational Biology | 2022 |
Pharmacokinetics, Tissue Distribution, and Excretion Characteristics of a Radix Polygoni Multiflori Extract in Rats. | Frontiers in Pharmacology | 2022 |
Dipeptide nanoparticle and aptamer-based hybrid fluorescence platform for enrofloxacin determination. | Mikrochimica Acta | 2022 |
Development of a bioanalytical method for the quantification of sinococuline in human plasma and its application in phase I clinical pharmacokinetic study. | Biomedical Chromatography | 2022 |
Determination of pharmacokinetic parameters and tissue distribution characters of enrofloxacin and its metabolite ciprofloxacin in Procambarus clarkii after two routes of administration | Aquaculture Reports | 2022 |
Development of a UPLC-MS/MS method for determination of a dual EZH1/2 inhibitor UNC1999 in rat plasma | Bioanalysis | 2022 |
Dixon's Q-test and Student's t-test to assess analog internal standard response in nonregulated LC-MS/MS bioanalysis | Bioanalysis | 2020 |
Population Pharmacokinetics and Exposure-Response Modeling of Daratumumab Subcutaneous Administration in Patients With Light-Chain Amyloidosis | Journal of Clinical Pharmacology | 2021 |
Determination of Prussian Blue Nanoparticles in Rat Tissue in the Presence of Endogenous Iron Interferences by Inductively Coupled Plasma – Optical Emission Spectrometry (ICP-OES) | Analytical Letters | 2020 |
Rapid and sensitive UHPLC-MS/MS methods for dietary sample analysis of 43 mycotoxins in China total diet study | Journal of Advanced Research | 2021 |
A developed HPLC-MS/MS method to quantitate 5 steriod hormones in clinical human serum by using PBS as the surrogate matrix | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2021 |
Single- and Multiple-Dose Pharmacokinetics and Safety of Vilaprisan in Healthy Postmenopausal Japanese Women: A Randomized Clinical Trial | European Journal of Drug Metabolism and Pharmacokinetics | 2021 |
Accelerating protein biomarker discovery and translation from proteomics research for clinical utility | Bioanalysis | 2020 |
A whole blood microsampling assay for vancomycin: development, validation and application for pediatric clinical study | Bioanalysis | 2020 |
Liquid chromatography-high resolution mass spectrometry for the determination of three cannabinoids, two (-)-trans-Δ-tetrahydrocannabinol metabolites, and six amphetamine-type stimulants in human hair | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
A simple and rapid LC-MS/MS method for the simultaneous determination of eight antipsychotics in human serum, and its application to therapeutic drug monitoring | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
Validation of Circulating Tumor DNA Assays for Detection of Metastatic Melanoma | Methods in Molecular Biology | 2020 |
A fast-screening dispersive liquid-liquid microextraction-gas chromatography-mass spectrometry method applied to the determination of efavirenz in human plasma samples | Analytical and Bioanalytical Chemistry | 2021 |
The relationship between plasma free fatty acids, cognitive function and structural integrity of the brain in middle-aged healthy humans | Aging | 2021 |
Qualitatively and quantitatively investigating the metabolism of 20(S)-protopanaxadiol-type ginsenosides by gut microbiota of different species | Biomedical Chromatography | 2021 |
Factors Influencing Plasma Coproporphyrin-I Concentration as Biomarker of OATP1B Activity in Patients With Rheumatoid Arthritis | Clinical Pharmacology and Therapeutics | 2021 |
Rapid Interference-free Analysis of β-Lapachone in Clinical Samples Using Liquid Chromatography-Mass Spectrometry for a Pharmacokinetic Study in Humans | Analytical Sciences | 2021 |
Simultaneous determination of eight catechins and four theaflavins in bottled tea by liquid chromatography-tandem mass spectrometry for forensic analysis | Journal of Forensic Sciences | 2021 |
Development and Validation of an Ultraperformance Liquid Chromatography-Tandem Mass Spectrometry Method for Quantitation of Total 3,3’,5-triiodo-L-Thyronine and 3,3’,5,5’-tetraiodo-L-Thyronine in Rodent Serum | Analytical Letters | |
Population Pharmacokinetics of Piperacillin and Tazobactam in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation: an ASAP ECMO Study | Antimicrobial Agents and Chemotherapy | 2021 |
Residues of glyphosate in food and dietary exposure | Comprehensive Reviews in Food Science and Food Safety | 2021 |
Simultaneous and rapid determination of 12 tyrosine kinase inhibitors by LC-MS/MS in human plasma: Application to therapeutic drug monitoring in patients with non-small cell lung cancer | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2021 |
An integrated outsourcing practice of nonclinical LC-MS bioanalysis and toxicokinetics at Novartis small molecule drug development | Bioanalysis | 2021 |
Pharmacokinetics of α-amanitin in mice using liquid chromatography-high resolution mass spectrometry and drug-drug interaction potentials | Journal of Toxicology and Environmental Health - Part A: Current Issues | 2021 |
Pharmacokinetic and metabolism study of ginsenoside Rb2 in rat by liquid chromatography combined with electrospray ionization tandem mass spectrometry | Biomedical Chromatography | 2021 |
Evaluation of an vivo neonatal extracorporeal membrane oxygenation circuit on antiepileptic drug sequestration | Perfusion (United Kingdom) | 2021 |
Population pharmacokinetics of intravenous and oral ciprofloxacin in children to optimize dosing regimens | European Journal of Clinical Pharmacology | 2021 |
Temperature-Dependent Residue Depletion Regularities of Tiamulin in Nile Tilapia () Following Multiple Oral Administrations | Frontiers in Veterinary Science | 2021 |
In-vitro and in-vivo metabolism of different aspirin formulations studied by a validated liquid chromatography tandem mass spectrometry method | Scientific Reports | 2021 |
Approaches to handling missing or "problematic" pharmacology data: Pharmacokinetics | CPT: Pharmacometrics and Systems Pharmacology | 2021 |
Amylin Analog Pramlintide Induces Migraine-like Attacks in Patients | Annals of Neurology | 2021 |
Effect of hepatic impairment on pharmacokinetics, safety, and tolerability of lemborexant | Pharmacology Research and Perspectives | 2021 |
A robust enzyme-linked immunosorbent assay to measure serum ramucirumab concentrations | Bioanalysis | 2021 |
Effect of severe renal impairment on pharmacokinetics, safety, and tolerability of lemborexant | Pharmacology Research and Perspectives | 2021 |
Radiopharmaceutical Validation for Clinical Use | Frontiers in Oncology | 2021 |
Development of a LC-MS/MS Method for the Quantification of Myricitrin: Application to a Pharmacokinetic Study in Rats | Revista Brasileira De Farmacognosia | 2021 |
Development and validation of a UHPLC-ESI-QTOF mass spectrometry method to analyze opines, plant biomarkers of crown gall or hairy root diseases | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2021 |
Nuclear magnetic resonance immunoassay of tetanus antibodies based on the displacement of magnetic nanoparticles | Analytical and Bioanalytical Chemistry | 2021 |
A novel isotope dilution UHPLC-ESI-MS/MS method for the quantification of 3-monochloropropane-1,2-diol in Caco-2 cell transport and receiving buffers | Food Additives and Contaminants - Part A Chemistry, Analysis, Control, Exposure and Risk Assessment | 2021 |
A validated LC-MS/MS method for the determination of RAF inhibitor LXH254: Application to pharmacokinetic study in rat | Biomedical Chromatography | 2021 |
Pharmacokinetics and metabolism of LNP023 in rats by liquid chromatography combined with electrospray ionization-tandem mass spectrometry | Biomedical Chromatography | 2021 |
Quantitative determination of phosphatidylethanol in dried blood spots for monitoring alcohol abstinence | Nature Protocols | 2021 |
Considerations in the development and validation of real-time quantitative polymerase chain reaction and its application in regulated bioanalysis to characterize the cellular kinetics of CAR-T products in clinical studies | Bioanalysis | 2021 |
Gentamicin plasma concentrations in hospitalized horses and retrospective minimal inhibitory concentrations of gram-negative equine pathogens | Journal of Veterinary Emergency and Critical Care | 2021 |
A fast and simple method for the simultaneous analysis of midazolam, 1-hydroxymidazolam, 4-hydroxymidazolam and 1-hydroxymidazolam glucuronide in human serum, plasma and urine | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2021 |
A feasibility study of metabolic phenotyping of dried blood spot specimens in rural Chinese women exposed to household air pollution | Journal of Exposure Science and Environmental Epidemiology | 2021 |
Comparison of sample preparation methods, validation of an UPLC-MS/MS procedure for the quantification of cyclosporine A in whole blood sample | Journal of Pharmaceutical and Biomedical Analysis | 2021 |
Exposure-Response and Population Pharmacokinetic Analyses of a Novel Subcutaneous Formulation of Daratumumab Administered to Multiple Myeloma Patients | Journal of Clinical Pharmacology | 2021 |
The effects of vilaprisan on the pharmacodynamics and pharmacokinetics of a combined oral contraceptive-A randomized controlled trial | British Journal of Clinical Pharmacology | 2021 |
An improved LC-MS/MS method for determination of docetaxel and its application to population pharmacokinetic study in Chinese cancer patients | Biomedical Chromatography | 2020 |
Use of standardized units for a correct interpretation of IC50 values obtained from the inhibition of the DPPH radical by natural antioxidants | Chemical Papers | 2020 |
A novel LC-MS/MS method for the determination of ziritaxestat in rat plasma and its pharmacokinetic study | Biomedical Chromatography | 2020 |
The Effects of Weak and Strong CYP3A Induction by Rifampicin on the Pharmacokinetics of Five Progestins and Ethinylestradiol Compared to Midazolam | Clinical Pharmacology and Therapeutics | 2020 |
An improved cytochrome P450 phenotyping cocktail with a simplified and highly sensitive UHPLC-MS/MS assay in human plasma | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
An HPLC method for simultaneous quantification of sunitinib and its active metabolite, SU12662, using hydrophilic interaction chromatography principle | Bioanalysis | 2020 |
LC-MS/MS determination of buparlisib, a phosphoinositide 3 kinase inhibitor in rat plasma: Application to a pharmacokinetic study | Biomedical Chromatography | 2020 |
Split First Dose Administration of Intravenous Daratumumab for the Treatment of Multiple Myeloma (MM): Clinical and Population Pharmacokinetic Analyses | Advances in Therapy | 2020 |
Development of a dried blood spot sampling method towards therapeutic monitoring of radotinib in the treatment of chronic myeloid leukaemia | Journal of Clinical Pharmacy and Therapeutics | 2020 |
Comparative pharmacokinetics of osmotic-controlled and immediate-release Eperisone tablet formulation in healthy human subjects using a sensitive plasma LC-ESI-MS/MS method | Scientific Reports | 2020 |
Validation and clinical application of a multiplex high performance liquid chromatography - tandem mass spectrometry assay for the monitoring of plasma concentrations of 12 antibiotics in patients with severe bacterial infections | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
Field-amplified sample injection in capillary zone electrophoresis for the pharmacokinetic research of trace risperidone and its major metabolite 9-hydroxyrisperidone in beagle dogs | Journal of Separation Science | 2020 |
AAPS Workshop Report on ICH M10 | AAPS Journal | 2019 |
Pharmacokinetic and bioavailability study of 5-hydroxy-4-methoxycanthin-6-one, a typical canthinone alkaloid, in rats using ultra-high performance liquid chromatography/electrospray ionization tandem mass spectrometry | Biomedical Chromatography | 2020 |
Metabolic Stability Assessment of New PARP Inhibitor Talazoparib Using Validated LC-MS/MS Methodology: In silico Metabolic Vulnerability and Toxicity Studies | Drug Design, Development and Therapy | 2020 |
LC-MS/MS method for the determination of erianin in rat plasma: Application to a pharmacokinetic study | Biomedical Chromatography | 2020 |
Development and validation of a mass spectrometry binding assay for mGlu5 receptor | Analytical and Bioanalytical Chemistry | 2020 |
Pharmacokinetics and bioavailability of ipatasertib in dog plasma using LC/MS/MS | Biomedical Chromatography | 2020 |
Determination of bromhexine and its metabolites in equine serum samples by liquid chromatography - Tandem mass spectrometry: Applicability to the elimination study after single oral dose | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
Pharmacokinetics, Safety, and Bioequivalence of Two Empagliflozin Formulations after Single Oral Administration under Fasting and Fed Conditions in Healthy Chinese Subjects: An Open-label Randomized Single-dose Two-sequence, Two-treatment, Two-period Crossover Study | Pharmacotherapy | 2020 |
Simultaneous determination of sutetinib and its active metabolite sutetinib N-oxide in human plasma by liquid chromatography-tandem mass spectrometry: Evaluation of plasma stability | Biomedical Chromatography | 2020 |
Targeted cutaneous delivery of etanercept using Er:YAG fractional laser ablation | International Journal of Pharmaceutics | 2020 |
Studies on the chiral separation of pheniramine and its enantioselective pharmacokinetics in rat plasma by HPLC-MS/MS | Microchemical Journal | 2020 |
Target Product Profiles for medical tests: a systematic review of current methods | BMC Medicine | 2020 |
Oral Fosfomycin Treatment for Enterococcal Urinary Tract Infections in a Dynamic Model | Antimicrobial Agents and Chemotherapy | 2020 |
Rapid and cost-effective LC-MS/MS method for determination of hydroxycitric acid in plasma: Application in the determination of pharmacokinetics in commercial Garcinia preparations | Biomedical Chromatography | 2020 |
A Study on Acetylglutamine Pharmacokinetics in Rat Blood and Brain Based on Liquid Chromatography-Tandem Mass Spectrometry and Microdialysis Technique | Frontiers in Pharmacology | 2020 |
Integration of Acoustic Liquid Handling into Quantitative Analysis of Biological Matrix Samples | SLAS Technology | 2020 |
QbD based Eudragit coated Meclizine HCl immediate and extended release multiparticulates: formulation, characterization and pharmacokinetic evaluation using HPLC-Fluorescence detection method | Scientific Reports | 2020 |
Quantitation of plasma and biliary cefpiramide concentrations in human samples using high-performance liquid chromatography | Biomedical Chromatography | 2020 |
An effective UFLC-MS/MS method used to study pharmacokinetics of major constituents of Fukeqianjin formula in rat plasma | Chinese Medicine | 2020 |
LC-MS-sMRM method development and validation of different classes of pain panel drugs and analysis of clinical urine samples | Basic and Clinical Pharmacology and Toxicology | 2020 |
Biodistribution of etoposide via intratumoral chemotherapy with etoposide-loaded implants | Drug Delivery | 2020 |
Quantitation of 2-hydroxyglutarate in human plasma via LC-MS/MS using a surrogate analyte approach | Bioanalysis | 2020 |
Pharmacokinetics and tissue distribution of remdesivir and its metabolites nucleotide monophosphate, nucleotide triphosphate, and nucleoside in mice | Acta Pharmacologica Sinica | 2021 |
Development and validation of a rapid and sensitive LC-MS/MS method for the determination of polyphyllin II in rat plasma and its application in a pharmacokinetic study | Biomedical Chromatography | 2020 |
Development and validation of LC-MS/MS methods to measure tobramycin and lincomycin in plasma, microdialysis fluid and urine: application to a pilot pharmacokinetic research study | Clinical Chemistry and Laboratory Medicine | 2020 |
A fatal case report of acute yohimbine intoxication | Forensic Toxicology | 2020 |
Novel high-performance liquid chromatography-tandem mass spectrometry method for simultaneous quantification of BCR-ABL and Bruton's tyrosine kinase inhibitors and their three active metabolites in human plasma | Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences | 2020 |
Evaluation of the 25-hydroxy vitamin D assay on a fully automated liquid chromatography mass spectrometry system, the Thermo Scientific Cascadion SM Clinical Analyzer with the Cascadion 25-hydroxy vitamin D assay in a routine clinical laboratory | Clinical Chemistry and Laboratory Medicine | 2020 |
Pharmacokinetic Similarity of ABP 710, a Proposed Biosimilar to Infliximab: Results From a Randomized, Single-Blind, Single-Dose, Parallel-Group Study in Healthy Subjects | Clinical Pharmacology in Drug Development | 2020 |
A rapid and sensitive method for quantification of ibrutinib in rat plasma by UPLC-ESI-MS/MS: validation and application to pharmacokinetic studies of a novel ibrutinib nanocrystalline | Biomedical Chromatography | 2020 |
An Ultrasensitive LC-APPI-MS/MS Method for Simultaneous Determination of Ciclesonide and Active Metabolite Desisobutyryl-Ciclesonide in Human Serum and Its Application to a Clinical Study | journal of applied laboratory medicine, The | 2020 |
Evaluating sample stability in the clinical laboratory with the help of linear and non-linear regression analysis | Clinical Chemistry and Laboratory Medicine | 2020 |
Automation of mass spectrometric detection of analytes and related workflows: A review | Talanta | 2020 |
Next-Generation DILI Biomarkers: Prioritization of Biomarkers for Qualification and Best Practices for Biospecimen Collection in Drug Development | Clinical Pharmacology and Therapeutics | 2020 |
Development and forensic validation of human genomic DNA quantification kit | International Journal of Legal Medicine | 2020 |
Relative Bioavailability of Enalapril Administered as Orodispersible Minitablets in Healthy Adults | Clinical Pharmacology in Drug Development | 2020 |
Local penetration of doxorubicin via intrahepatic implantation of PLGA based doxorubicin-loaded implants | Drug Delivery | 2019 |
A Population Pharmacokinetic Model-Guided Evaluation of Ceftolozane-Tazobactam Dosing in Critically Ill Patients Undergoing Continuous Venovenous Hemodiafiltration | Antimicrobial Agents and Chemotherapy | 2019 |
Pharmacokinetics and metabolism of icaritin in rats by UPLC-MS/MS | Food Science and Nutrition | 2019 |
Use of 4β-Hydroxycholesterol Plasma Concentrations as an Endogenous Biomarker of CYP3A Activity: Clinical Validation in Individuals With Type 2 Diabetes | Clinical Pharmacology and Therapeutics | 2019 |
Effect of Dietary Doses of Quercetin on Hepatic Drug Metabolizing Enzymes in Spontaneously Hypertensive Rats | European Journal of Drug Metabolism and Pharmacokinetics | 2019 |
Randomized, Double-Blind, Placebo-Controlled, Single-Ascending-Dose Study of the Penetration of a Monoclonal Antibody Combination (ASN100) Targeting Cytotoxins in the Lung Epithelial Lining Fluid of Healthy Volunteers | Antimicrobial Agents and Chemotherapy | 2019 |
Mass Spectrometry-Sensitive Probes Coupled with Direct Analysis in Real Time for Simultaneous Sensing of Chemical and Biological Properties of Botanical Drugs | Analytical Chemistry | 2019 |
An LC-MS/MS method for quantification of HR011303, a novel highly selective urate transporter 1 inhibitor in beagle dogs and the application to a pharmacokinetic study | Biomedical Chromatography | 2019 |
Fit-for-Purpose Quality Control System in Continuous Bioanalysis During Long-Term Pediatric Studies | AAPS Journal | 2019 |
Stability of the Human Plasma Proteome to Pre-analytical Variability as Assessed by an Aptamer-Based Approach | Journal of Proteome Research | 2019 |
An Accurate Substitution Method To Minimize Left Censoring Bias in Serum Steroid Measurements | Endocrinology | 2019 |
Modeling the influence of time and temperature on the levels of fatty acids in the liver of Antarctic fish Trematomus bernacchii | Polar Biology | 2019 |
Screening Bioactive Compounds of Siraitia grosvenorii by Immobilized β-Adrenergic Receptor Chromatography and Druggability Evaluation | Frontiers in Pharmacology | 2019 |
Population Pharmacokinetics of Unbound Ceftolozane and Tazobactam in Critically Ill Patients without Renal Dysfunction | Antimicrobial Agents and Chemotherapy | 2019 |
Development and validation of a simple method for the extraction and quantification of crisaborole in skin layers | Biomedical Chromatography | 2019 |
Simultaneous bioanalysis and pharmacokinetic interaction study of acebrophylline, levocetirizine and pranlukast in Sprague-Dawley rats | Biomedical Chromatography | 2019 |
Development and Validation of LC–MS Method for the Estimation of N-Acetyl-Tryptophan and its Impurities Under Stress Conditions | Chromatographia | 2019 |