5.5(top 2%)
Impact Factor
5.9(top 2%)
extended IF
104(top 3%)
citing journals
citing authors

Most Cited Articles of Aging in 2016

Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies2016528
DNA methylation-based measures of biological age: meta-analysis predicting time to death2016505
Markers of cellular senescence. Telomere shortening as a marker of cellular senescence2016181
Aging of mice is associated with p16(Ink4a)- and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells2016175
Deep biomarkers of human aging: Application of deep neural networks to biomarker development2016160
The protective role of Sirt1 in vascular tissue: its relationship to vascular aging and atherosclerosis2016143
NKG2D ligands mediate immunosurveillance of senescent cells2016141
Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels2016131
Discovery of piperlongumine as a potential novel lead for the development of senolytic agents2016124
Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses2016124
Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markers2016121
Age-related deficits in skeletal muscle recovery following disuse are associated with neuromuscular junction instability and ER stress, not impaired protein synthesis2016110
Long-term moderate calorie restriction inhibits inflammation without impairing cell-mediated immunity: a randomized controlled trial in non-obese humans201696
DNA methylation levels at individual age-associated CpG sites can be indicative for life expectancy201692
Placental membrane aging and HMGB1 signaling associated with human parturition201684
MicroRNA-346 facilitates cell growth and metastasis, and suppresses cell apoptosis in human non-small cell lung cancer by regulation of XPC/ERK/Snail/E-cadherin pathway201683
Reversal of cognitive decline in Alzheimer's disease201680
Bedaquiline, an FDA-approved antibiotic, inhibits mitochondrial function and potently blocks the proliferative expansion of stem-like cancer cells (CSCs)201679
MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4201679
Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants201679
Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts201674
Aging of immune system: Immune signature from peripheral blood lymphocyte subsets in 1068 healthy adults201669
Rapamycin reverses the senescent phenotype and improves immunoregulation of mesenchymal stem cells from MRL/lpr mice and systemic lupus erythematosus patients through inhibition of the mTOR signaling pathway201668
Increased expression of long-noncoding RNA ZFAS1 is associated with epithelial-mesenchymal transition of gastric cancer201665
Epigenetic age predictions based on buccal swabs are more precise in combination with cell type-specific DNA methylation signatures201664