| 1 | Managing Clinical Knowledge for Health Care Improvement | Yearbook of Medical Informatics | 2000 | 790 |
| 2 | Electronic Health Records: Then, Now, and in the Future | Yearbook of Medical Informatics | 2016 | 508 |
| 3 | Extracting Information from Textual Documents in the Electronic Health Record: A Review of Recent Research | Yearbook of Medical Informatics | 2008 | 404 |
| 4 | AI in Health: State of the Art, Challenges, and Future Directions | Yearbook of Medical Informatics | 2019 | 302 |
| 5 | Artificial Intelligence in Clinical Decision Support: Challenges for Evaluating AI and Practical Implications | Yearbook of Medical Informatics | 2019 | 259 |
| 6 | Technologies for an Aging Society: A Systematic Review of “Smart Home” Applications | Yearbook of Medical Informatics | 2008 | 258 |
| 7 | Clinical Decision Support: a 25 Year Retrospective and a 25 Year Vision | Yearbook of Medical Informatics | 2016 | 208 |
| 8 | Biomedical Ontologies in Action: Role in Knowledge Management, Data Integration and Decision Support | Yearbook of Medical Informatics | 2008 | 186 |
| 9 | Clinical Data Reuse or Secondary Use: Current Status and Potential Future Progress | Yearbook of Medical Informatics | 2017 | 172 |
| 10 | Recent Developments in Clinical Terminologies — SNOMED CT, LOINC, and RxNorm | Yearbook of Medical Informatics | 2018 | 158 |
| 11 | Big Data and Biomedical Informatics: A Challenging Opportunity | Yearbook of Medical Informatics | 2014 | 153 |
| 12 | Artificial Intelligence in Primary Health Care: Perceptions, Issues, and Challenges | Yearbook of Medical Informatics | 2019 | 153 |
| 13 | Role of Artificial Intelligence within the Telehealth Domain | Yearbook of Medical Informatics | 2019 | 150 |
| 14 | Ethical Issues of Social Media Usage in Healthcare | Yearbook of Medical Informatics | 2015 | 146 |
| 15 | mHealth - an Ultimate Platform to Serve the Unserved | Yearbook of Medical Informatics | 2010 | 143 |
| 16 | Big Data in Medicine Is Driving Big Changes | Yearbook of Medical Informatics | 2014 | 141 |
| 17 | Human Factors and Usability for Health Information Technology: Old and New Challenges | Yearbook of Medical Informatics | 2019 | 141 |
| 18 | “Big Data” and the Electronic Health Record | Yearbook of Medical Informatics | 2014 | 138 |
| 19 | Toward an Information Infrastructure for Global Health Improvement | Yearbook of Medical Informatics | 2017 | 127 |
| 20 | Health Information Management: Implications of Artificial Intelligence on Healthcare Data and Information Management | Yearbook of Medical Informatics | 2019 | 122 |
| 21 | The Unified Medical Language System | Yearbook of Medical Informatics | 1993 | 121 |
| 22 | Capturing the Patient’s Perspective: a Review of Advances in Natural Language Processing of Health-Related Text | Yearbook of Medical Informatics | 2017 | 112 |
| 23 | Public and Population Health Informatics: The Bridging of Big Data to Benefit Communities | Yearbook of Medical Informatics | 2018 | 109 |
| 24 | Artificial Intelligence in Clinical Decision Support: a Focused Literature Survey | Yearbook of Medical Informatics | 2019 | 105 |
| 25 | Big Data in Science and Healthcare: A Review of Recent Literature and Perspectives | Yearbook of Medical Informatics | 2014 | 104 |
| 26 | Beginnings of Artificial Intelligence in Medicine (AIM): Computational Artifice Assisting Scientific Inquiry and Clinical Art – with Reflections on Present AIM Challenges | Yearbook of Medical Informatics | 2019 | 104 |
| 27 | A Review and Framework for Categorizing Current Research and Development in Health Related Geographical Information Systems (GIS) Studies | Yearbook of Medical Informatics | 2014 | 93 |
| 28 | What is bioinformatics? An introduction and overview | Yearbook of Medical Informatics | 2001 | 83 |
| 29 | Present and Future Trends in Consumer Health Informatics and Patient-Generated Health Data | Yearbook of Medical Informatics | 2017 | 82 |
| 30 | Recent Advances in Using Natural Language Processing to Address Public Health Research Questions Using Social Media and ConsumerGenerated Data | Yearbook of Medical Informatics | 2019 | 80 |
| 31 | Serious Games in Health Professions Education: Review of Trends and Learning Efficacy | Yearbook of Medical Informatics | 2019 | 80 |
| 32 | Deep Learning on 1-D Biosignals: a Taxonomy-based Survey | Yearbook of Medical Informatics | 2018 | 71 |
| 33 | Medical Information Extraction in the Age of Deep Learning | Yearbook of Medical Informatics | 2020 | 70 |
| 34 | Advancing Medical Imaging Informatics by Deep Learning-Based Domain Adaptation | Yearbook of Medical Informatics | 2020 | 69 |
| 35 | The Unintended Consequences of Health Information Technology Revisited | Yearbook of Medical Informatics | 2016 | 66 |
| 36 | Consumer Health Informatics Adoption among Underserved Populations: Thinking beyond the Digital Divide | Yearbook of Medical Informatics | 2018 | 66 |
| 37 | Patient Identification Techniques – Approaches, Implications, and Findings | Yearbook of Medical Informatics | 2020 | 65 |
| 38 | Technical Challenges for Big Data in Biomedicine and Health: Data Sources, Infrastructure, and Analytics | Yearbook of Medical Informatics | 2014 | 64 |
| 39 | Patient Portals as a Means of Information and Communication Technology Support to Patient-Centric Care Coordination – the Missing Evidence and the Challenges of Evaluation | Yearbook of Medical Informatics | 2015 | 62 |
| 40 | New Unintended Adverse Consequences of Electronic Health Records | Yearbook of Medical Informatics | 2016 | 62 |
| 41 | Clinical Decision Support and Implications for the Clinician Burnout Crisis | Yearbook of Medical Informatics | 2020 | 62 |
| 42 | The Agenda of Wearable Healthcare | Yearbook of Medical Informatics | 2005 | 61 |
| 43 | Recent Advances in Clinical Natural Language Processing in Support of Semantic Analysis | Yearbook of Medical Informatics | 2015 | 60 |
| 44 | Current Challenges and Opportunities for Better Integration of Human Factors Research with Development of Clinical Information Systems | Yearbook of Medical Informatics | 2009 | 58 |
| 45 | IBM’s Health Analytics and Clinical Decision Support | Yearbook of Medical Informatics | 2014 | 58 |
| 46 | The French Health Data Hub and the German Medical Informatics Initiatives: Two National Projects to Promote Data Sharing in Healthcare | Yearbook of Medical Informatics | 2019 | 58 |
| 47 | The Use and Promise of Conversational Agents in Digital Health | Yearbook of Medical Informatics | 2021 | 58 |
| 48 | Developments in Privacy and Data Ownership in Mobile Health Technologies, 2016-2019 | Yearbook of Medical Informatics | 2020 | 57 |
| 49 | Consumer Health Informatics: Past, Present, and Future of a Rapidly Evolving Domain | Yearbook of Medical Informatics | 2016 | 56 |
| 50 | Unintended Consequences of Tele Health and their Possible Solutions | Yearbook of Medical Informatics | 2016 | 55 |