| 1 | What are biomarkers? | Current Opinion in HIV and AIDS | 2010 | 1,256 |
| 2 | Trends in life expectancy of HIV-positive adults on antiretroviral therapy across the globe | Current Opinion in HIV and AIDS | 2016 | 306 |
| 3 | Contribution of sexually transmitted infections to the sexual transmission of HIV | Current Opinion in HIV and AIDS | 2010 | 237 |
| 4 | HIV subtype diversity worldwide | Current Opinion in HIV and AIDS | 2019 | 237 |
| 5 | Long-acting injectable antiretrovirals for HIV treatment and prevention | Current Opinion in HIV and AIDS | 2013 | 214 |
| 6 | HIV treatment as prevention and HPTN 052 | Current Opinion in HIV and AIDS | 2012 | 202 |
| 7 | Microbial translocation and microbiome dysbiosis in HIV-associated immune activation | Current Opinion in HIV and AIDS | 2016 | 199 |
| 8 | The global epidemic of HIV infection among men who have sex with men | Current Opinion in HIV and AIDS | 2009 | 180 |
| 9 | HIV epidemics among transgender women | Current Opinion in HIV and AIDS | 2014 | 170 |
| 10 | Tissue reservoirs of HIV | Current Opinion in HIV and AIDS | 2016 | 170 |
| 11 | Biomarkers of immune dysfunction in HIV | Current Opinion in HIV and AIDS | 2010 | 155 |
| 12 | Evolving epidemiology of HIV-associated malignancies | Current Opinion in HIV and AIDS | 2017 | 155 |
| 13 | Formulation and pharmacology of long-acting cabotegravir | Current Opinion in HIV and AIDS | 2015 | 151 |
| 14 | The biology of CCR5 and CXCR4 | Current Opinion in HIV and AIDS | 2009 | 150 |
| 15 | HIV/hepatitis C coinfection natural history and disease progression | Current Opinion in HIV and AIDS | 2011 | 149 |
| 16 | Persistent HIV-1 replication during antiretroviral therapy | Current Opinion in HIV and AIDS | 2016 | 145 |
| 17 | HIV infection among female sex workers in concentrated and high prevalence epidemics | Current Opinion in HIV and AIDS | 2014 | 143 |
| 18 | Role of acute and early HIV infection in the sexual transmission of HIV | Current Opinion in HIV and AIDS | 2010 | 141 |
| 19 | The molecular biology of HIV latency: breaking and restoring the Tat-dependent transcriptional circuit | Current Opinion in HIV and AIDS | 2011 | 138 |
| 20 | Tenofovir and bone health | Current Opinion in HIV and AIDS | 2016 | 137 |
| 21 | Current concepts for PrEP adherence in the PrEP revolution | Current Opinion in HIV and AIDS | 2016 | 133 |
| 22 | Human papillomavirus-related disease in people with HIV | Current Opinion in HIV and AIDS | 2009 | 130 |
| 23 | The global epidemiology of adolescents living with HIV | Current Opinion in HIV and AIDS | 2018 | 128 |
| 24 | The interplay between HIV and COVID-19: summary of the data and responses to date | Current Opinion in HIV and AIDS | 2021 | 125 |
| 25 | Th17 cytokines in mucosal immunity and inflammation | Current Opinion in HIV and AIDS | 2010 | 124 |
| 26 | HIV-1-specific antibody responses during acute and chronic HIV-1 infection | Current Opinion in HIV and AIDS | 2009 | 123 |
| 27 | Epidemiology and clinical characteristics of elite controllers | Current Opinion in HIV and AIDS | 2011 | 122 |
| 28 | The mucosal barrier and immune activation in HIV pathogenesis | Current Opinion in HIV and AIDS | 2008 | 121 |
| 29 | Epidemiology of HIV-associated tuberculosis | Current Opinion in HIV and AIDS | 2009 | 120 |
| 30 | Shocking HIV out of hiding | Current Opinion in HIV and AIDS | 2016 | 118 |
| 31 | Retention and adherence | Current Opinion in HIV and AIDS | 2018 | 116 |
| 32 | The role of healthcare providers in the roll out of preexposure prophylaxis | Current Opinion in HIV and AIDS | 2016 | 115 |
| 33 | Kaposi sarcoma herpesvirus-associated cancers and related diseases | Current Opinion in HIV and AIDS | 2017 | 115 |
| 34 | HIV and ageing | Current Opinion in HIV and AIDS | 2016 | 113 |
| 35 | Genital inflammation, immune activation and risk of sexual HIV acquisition | Current Opinion in HIV and AIDS | 2016 | 113 |
| 36 | Residual inflammation and viral reservoirs | Current Opinion in HIV and AIDS | 2016 | 112 |
| 37 | Overview of STEP and Phambili trial results: two phase IIb test-of-concept studies investigating the efficacy of MRK adenovirus type 5 gag/pol/nef subtype B HIV vaccine | Current Opinion in HIV and AIDS | 2010 | 111 |
| 38 | Highly active antiretroviral treatment as prevention of HIV transmission: review of scientific evidence and update | Current Opinion in HIV and AIDS | 2010 | 109 |
| 39 | Th17 and regulatory T cells: implications for AIDS pathogenesis | Current Opinion in HIV and AIDS | 2010 | 109 |
| 40 | The hepatitis C virus epidemics in key populations (including people who inject drugs, prisoners and MSM) | Current Opinion in HIV and AIDS | 2015 | 108 |
| 41 | Lenacapavir: a first-in-class HIV-1 capsid inhibitor | Current Opinion in HIV and AIDS | 2022 | 107 |
| 42 | Where does HIV hide? A focus on the central nervous system | Current Opinion in HIV and AIDS | 2013 | 106 |
| 43 | Overcoming pharmacologic sanctuaries | Current Opinion in HIV and AIDS | 2013 | 106 |
| 44 | Cell-to-cell HIV-1 spread and its implications for immune evasion | Current Opinion in HIV and AIDS | 2009 | 104 |
| 45 | HIV broadly neutralizing antibody targets | Current Opinion in HIV and AIDS | 2015 | 103 |
| 46 | Concentrated HIV subepidemics in generalized epidemic settings | Current Opinion in HIV and AIDS | 2014 | 100 |
| 47 | Th17 cell dynamics in HIV infection | Current Opinion in HIV and AIDS | 2010 | 99 |
| 48 | Histone deacetylase inhibitors and HIV latency | Current Opinion in HIV and AIDS | 2011 | 99 |
| 49 | Quality and quantity | Current Opinion in HIV and AIDS | 2012 | 99 |
| 50 | HIV treatment cascade in MSM, people who inject drugs, and sex workers | Current Opinion in HIV and AIDS | 2015 | 98 |