| 1 | Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty | Nature Reviews Cardiology | 2018 | 2,656 |
| 2 | Third universal definition of myocardial infarction | Nature Reviews Cardiology | 2012 | 2,050 |
| 3 | Epidemiology and risk profile of heart failure | Nature Reviews Cardiology | 2010 | 1,393 |
| 4 | The inflammatory response in myocardial injury, repair, and remodelling | Nature Reviews Cardiology | 2014 | 1,341 |
| 5 | Epidemiology and aetiology of heart failure | Nature Reviews Cardiology | 2016 | 1,338 |
| 6 | Mechanisms of physiological and pathological cardiac hypertrophy | Nature Reviews Cardiology | 2018 | 1,276 |
| 7 | Epidemiology of heart failure with preserved ejection fraction | Nature Reviews Cardiology | 2017 | 1,140 |
| 8 | Global epidemiology, health burden and effective interventions for elevated blood pressure and hypertension | Nature Reviews Cardiology | 2021 | 1,062 |
| 9 | Epidemiology of cardiovascular disease in China: current features and implications | Nature Reviews Cardiology | 2018 | 1,049 |
| 10 | Myocardial ischaemia–reperfusion injury and cardioprotection in perspective | Nature Reviews Cardiology | 2020 | 999 |
| 11 | Myocarditis and inflammatory cardiomyopathy: current evidence and future directions | Nature Reviews Cardiology | 2020 | 898 |
| 12 | COVID-19 and cardiovascular disease: from basic mechanisms to clinical perspectives | Nature Reviews Cardiology | 2020 | 891 |
| 13 | The molecular and metabolic landscape of iron and ferroptosis in cardiovascular disease | Nature Reviews Cardiology | 2022 | 877 |
| 14 | Stress and cardiovascular disease | Nature Reviews Cardiology | 2012 | 875 |
| 15 | Epidemiology of venous thromboembolism | Nature Reviews Cardiology | 2015 | 873 |
| 16 | Vascular smooth muscle cells in atherosclerosis | Nature Reviews Cardiology | 2019 | 871 |
| 17 | Inflammation and the pathogenesis of atrial fibrillation | Nature Reviews Cardiology | 2015 | 842 |
| 18 | Platelet biology and functions: new concepts and clinical perspectives | Nature Reviews Cardiology | 2018 | 790 |
| 19 | Effects of stress on the development and progression of cardiovascular disease | Nature Reviews Cardiology | 2017 | 784 |
| 20 | Inflammation and its resolution in atherosclerosis: mediators and therapeutic opportunities | Nature Reviews Cardiology | 2019 | 768 |
| 21 | PPAR control of metabolism and cardiovascular functions | Nature Reviews Cardiology | 2021 | 768 |
| 22 | Interplay between inflammation and thrombosis in cardiovascular pathology | Nature Reviews Cardiology | 2021 | 762 |
| 23 | Dilated cardiomyopathy: the complexity of a diverse genetic architecture | Nature Reviews Cardiology | 2013 | 747 |
| 24 | Obesity, inflammation, and atherosclerosis | Nature Reviews Cardiology | 2009 | 711 |
| 25 | Monocytes in atherosclerosis: subsets and functions | Nature Reviews Cardiology | 2010 | 666 |
| 26 | Pathophysiology and epidemiology of abdominal aortic aneurysms | Nature Reviews Cardiology | 2011 | 652 |
| 27 | Global epidemiology of dyslipidaemias | Nature Reviews Cardiology | 2021 | 647 |
| 28 | Mitochondrial function as a therapeutic target in heart failure | Nature Reviews Cardiology | 2016 | 633 |
| 29 | Nitric oxide signalling in cardiovascular health and disease | Nature Reviews Cardiology | 2018 | 630 |
| 30 | Mechanisms of disease: pulmonary arterial hypertension | Nature Reviews Cardiology | 2011 | 625 |
| 31 | Dysfunctional HDL and atherosclerotic cardiovascular disease | Nature Reviews Cardiology | 2015 | 619 |
| 32 | Mechanisms of diabetic cardiomyopathy and potential therapeutic strategies: preclinical and clinical evidence | Nature Reviews Cardiology | 2020 | 613 |
| 33 | Dietary metabolism, the gut microbiome, and heart failure | Nature Reviews Cardiology | 2018 | 609 |
| 34 | Assessment and management of blood-pressure variability | Nature Reviews Cardiology | 2013 | 608 |
| 35 | Abdominal aortic aneurysm: update on pathogenesis and medical treatments | Nature Reviews Cardiology | 2018 | 604 |
| 36 | Myocardial remodeling after infarction: the role of myofibroblasts | Nature Reviews Cardiology | 2009 | 602 |
| 37 | Exercise benefits in cardiovascular disease: beyond attenuation of traditional risk factors | Nature Reviews Cardiology | 2018 | 598 |
| 38 | Reappraising the role of inflammation in heart failure | Nature Reviews Cardiology | 2020 | 595 |
| 39 | Epidemiology of cardiovascular disease in Europe | Nature Reviews Cardiology | 2021 | 593 |
| 40 | SGLT2 inhibitors: mechanisms of cardiovascular benefit beyond glycaemic control | Nature Reviews Cardiology | 2020 | 585 |
| 41 | Artificial intelligence-enhanced electrocardiography in cardiovascular disease management | Nature Reviews Cardiology | 2021 | 572 |
| 42 | Environmental determinants of cardiovascular disease: lessons learned from air pollution | Nature Reviews Cardiology | 2020 | 568 |
| 43 | Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine | Nature Reviews Cardiology | 2020 | 564 |
| 44 | Endoplasmic reticulum stress and unfolded protein response in cardiovascular diseases | Nature Reviews Cardiology | 2021 | 564 |
| 45 | The NLRP3 inflammasome in acute myocardial infarction | Nature Reviews Cardiology | 2017 | 562 |
| 46 | T cell subsets and functions in atherosclerosis | Nature Reviews Cardiology | 2020 | 560 |
| 47 | Global epidemiology of valvular heart disease | Nature Reviews Cardiology | 2021 | 559 |
| 48 | The pathophysiology of heart failure with preserved ejection fraction | Nature Reviews Cardiology | 2014 | 551 |
| 49 | Adverse cardiac effects of cancer therapies: cardiotoxicity and arrhythmia | Nature Reviews Cardiology | 2020 | 548 |
| 50 | The changing epidemiology of congenital heart disease | Nature Reviews Cardiology | 2010 | 541 |
