| 1 | A review on Alzheimer's disease pathophysiology and its management: an update | Pharmacological Reports | 2015 | 1,411 |
| 2 | Nanoparticles as drug delivery systems | Pharmacological Reports | 2012 | 1,228 |
| 3 | Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron | Pharmacological Reports | 2009 | 681 |
| 4 | ICAM-1 signaling in endothelial cells | Pharmacological Reports | 2009 | 604 |
| 5 | Drug repurposing approach to fight COVID-19 | Pharmacological Reports | 2020 | 408 |
| 6 | Therapeutic strategies for Alzheimer's disease in clinical trials | Pharmacological Reports | 2016 | 404 |
| 7 | Lipoic acid – biological activity and therapeutic potential | Pharmacological Reports | 2011 | 389 |
| 8 | Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide | Pharmacological Reports | 2010 | 380 |
| 9 | Treatment of inflammatory bowel disease (IBD) | Pharmacological Reports | 2011 | 373 |
| 10 | COX-2 as a target for cancer chemotherapy | Pharmacological Reports | 2010 | 306 |
| 11 | Physiology and pharmacology of melatonin in relation to biological rhythms | Pharmacological Reports | 2009 | 284 |
| 12 | Role of NF-κB in the pathogenesis of diabetes and its associated complications | Pharmacological Reports | 2009 | 270 |
| 13 | The Nrf2-ARE signaling pathway: An update on its regulation and possible role in cancer prevention and treatment | Pharmacological Reports | 2017 | 270 |
| 14 | Antihypertensive effects of the flavonoid quercetin | Pharmacological Reports | 2009 | 266 |
| 15 | Fructose-fed streptozotocin-injected rat: an alternative model for type 2 diabetes | Pharmacological Reports | 2012 | 252 |
| 16 | Drug resistance in cancer: mechanisms and tackling strategies | Pharmacological Reports | 2020 | 238 |
| 17 | Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders. Part 2. Depression, anxiety, schizophrenia and autism | Pharmacological Reports | 2015 | 236 |
| 18 | Early maternal separation: a rodent model of depression and a prevailing human condition | Pharmacological Reports | 2013 | 235 |
| 19 | Animal models of acute renal failure | Pharmacological Reports | 2012 | 218 |
| 20 | Prodrugs: A challenge for the drug development | Pharmacological Reports | 2013 | 213 |
| 21 | Cytokines, prostaglandins and nitric oxide in the regulation of stress-response systems | Pharmacological Reports | 2013 | 202 |
| 22 | Lipid peroxidation and antioxidant protection in patients during acute depressive episodes and in remission after fluoxetine treatment | Pharmacological Reports | 2009 | 198 |
| 23 | Biochemical and pharmacological characterization of isatin and its derivatives: from structure to activity | Pharmacological Reports | 2013 | 198 |
| 24 | Berberine and neurodegeneration: A review of literature | Pharmacological Reports | 2015 | 198 |
| 25 | Chemical structure of phenothiazines and their biological activity | Pharmacological Reports | 2012 | 194 |
| 26 | Regulation of sphingomyelin metabolism | Pharmacological Reports | 2016 | 185 |
| 27 | Third-generation antiepileptic drugs: mechanisms of action, pharmacokinetics and interactions | Pharmacological Reports | 2009 | 183 |
| 28 | A review on antioxidant potential of bioactive heterocycle benzofuran: Natural and synthetic derivatives | Pharmacological Reports | 2017 | 183 |
| 29 | Statin-induced myopathies | Pharmacological Reports | 2011 | 182 |
| 30 | Overview on 5-HT receptors and their role in physiology and pathology of the central nervous system | Pharmacological Reports | 2009 | 177 |
| 31 | Vitamin D and the central nervous system | Pharmacological Reports | 2013 | 171 |
| 32 | Cytochrome P450–dependent metabolism of ω-6 and ω-3 long-chain polyunsaturated fatty acids | Pharmacological Reports | 2010 | 164 |
| 33 | Beneficial roles of honey polyphenols against some human degenerative diseases: A review | Pharmacological Reports | 2017 | 161 |
| 34 | LL-37: Cathelicidin-related antimicrobial peptide with pleiotropic activity | Pharmacological Reports | 2016 | 149 |
| 35 | Scavenging and antioxidant potential of physiological taurine concentrations against different reactive oxygen/nitrogen species | Pharmacological Reports | 2010 | 143 |
| 36 | Natural and synthetic acridines/acridones as antitumor agents: their biological activities and methods of synthesis | Pharmacological Reports | 2011 | 142 |
| 37 | Essential elements in depression and anxiety. Part I | Pharmacological Reports | 2014 | 138 |
| 38 | Impact of endocrine-disrupting chemicals on neural development and the onset of neurological disorders | Pharmacological Reports | 2013 | 137 |
| 39 | Anti-inflammatory and ameliorative effects of gallic acid on fluoxetine-induced oxidative stress and liver damage in rats | Pharmacological Reports | 2017 | 137 |
| 40 | Hydrogen sulfide in pharmacology and medicine – An update | Pharmacological Reports | 2015 | 135 |
| 41 | Role of oxidative stress in epileptogenesis and potential implications for therapy | Pharmacological Reports | 2020 | 135 |
| 42 | Tramadol as an analgesic for mild to moderate cancer pain | Pharmacological Reports | 2009 | 134 |
| 43 | Oxidative stress, polyunsaturated fatty acidsderived oxidation products and bisretinoids as potential inducers of CNS diseases: focus on age-related macular degeneration | Pharmacological Reports | 2013 | 134 |
| 44 | Hyaluronan: Towards novel anti-cancer therapeutics | Pharmacological Reports | 2013 | 130 |
| 45 | Resveratrol improves diabetic retinopathy possibly through oxidative stress – nuclear factor κB – apoptosis pathway | Pharmacological Reports | 2012 | 126 |
| 46 | Food, nutrients and nutraceuticals affecting the course of inflammatory bowel disease | Pharmacological Reports | 2016 | 126 |
| 47 | Oxidative stress markers in affective disorders | Pharmacological Reports | 2013 | 125 |
| 48 | Efficacy of single and repeated administration of ketamine in unipolar and bipolar depression: a meta-analysis of randomized clinical trials | Pharmacological Reports | 2020 | 121 |
| 49 | Nanostructured lipid carriers: A potential use for skin drug delivery systems | Pharmacological Reports | 2019 | 119 |
| 50 | Research advances in basic mechanisms of seizures and antiepileptic drug action | Pharmacological Reports | 2013 | 118 |
