38.5(top 0.1%)
2-year impact
40.4(top 0.1%)
3-year impact
39.9(top 0.1%)
5-year impact
30.7(top 0.1%)
10-year impact
2.4K(top 10%)
PR articles
548.8K(top 1%)
PR citations
384(top 1%)
PR h-index
427(top 0.1%)
h-index
41.1(top 0.1%)
extended IF
33.2(top 0.1%)
2-YI (article-only)
97.6(top 0.1%)
2-YI (review-only)
38.0(top 0.1%)
2-YI (no self-cite.)
2.7K
documents
706.1K
doc citations

Top Articles

#TitleJournalYearPR Citations
1Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1Cancer Cell20105,542
2Tensional homeostasis and the malignant phenotypeCancer Cell20052,916
3Integrative Genomic Profiling of Human Prostate CancerCancer Cell20102,871
4Polarization of Tumor-Associated Neutrophil Phenotype by TGF-β: “N1” versus “N2” TANCancer Cell20092,621
5The evolving tumor microenvironment: From cancer initiation to metastatic outgrowthCancer Cell20232,497
6A collection of breast cancer cell lines for the study of functionally distinct cancer subtypesCancer Cell20062,379
7Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesisCancer Cell20062,323
8Unique microRNA molecular profiles in lung cancer diagnosis and prognosisCancer Cell20062,316
9Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosisCancer Cell20052,247
10Defining the Role of mTOR in CancerCancer Cell20072,228
11Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent DioxygenasesCancer Cell20112,196
12Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic DifferentiationCancer Cell20102,061
13Targeting Ferroptosis to Iron Out CancerCancer Cell20191,963
14Oxidative Stress in CancerCancer Cell20201,960
15Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced SurvivalCancer Cell20141,952
16Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in miceCancer Cell20051,895
17Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouseCancer Cell20031,829
18A multigenic program mediating breast cancer metastasis to boneCancer Cell20031,825
19Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant MetastasisCancer Cell20091,793
20Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of GliomaCancer Cell20101,777
21Tumor Cell Metabolism: Cancer's Achilles' HeelCancer Cell20081,773
22Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell linesCancer Cell20061,768
23IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated CancerCancer Cell20091,765
24Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal AdenocarcinomaCancer Cell20121,636
25Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylaseCancer Cell20051,630
26Stromal Elements Act to Restrain, Rather Than Support, Pancreatic Ductal AdenocarcinomaCancer Cell20141,582
27Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesisCancer Cell20061,576
28A Perivascular Niche for Brain Tumor Stem CellsCancer Cell20071,556
29The Common Feature of Leukemia-Associated IDH1 and IDH2 Mutations Is a Neomorphic Enzyme Activity Converting α-Ketoglutarate to 2-HydroxyglutarateCancer Cell20101,554
30YAP/TAZ at the Roots of CancerCancer Cell20161,513
31Direct Signaling between Platelets and Cancer Cells Induces an Epithelial-Mesenchymal-Like Transition and Promotes MetastasisCancer Cell20111,441
32Integrated Genomic Characterization of Pancreatic Ductal AdenocarcinomaCancer Cell20171,421
33Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of GlioblastomaCancer Cell20121,392
34Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the MicroenvironmentCancer Cell20171,371
35Identification of Distinct Basal and Luminal Subtypes of Muscle-Invasive Bladder Cancer with Different Sensitivities to Frontline ChemotherapyCancer Cell20141,322
36NRF2 and the Hallmarks of CancerCancer Cell20181,313
37PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patientsCancer Cell20041,302
38Attenuation of LDH-A expression uncovers a link between glycolysis, mitochondrial physiology, and tumor maintenanceCancer Cell20061,280
39A Long Noncoding RNA Activated by TGF-β Promotes the Invasion-Metastasis Cascade in Hepatocellular CarcinomaCancer Cell20141,279
40AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma PatientsCancer Cell20071,273
41Fibroblast Heterogeneity and Immunosuppressive Environment in Human Breast CancerCancer Cell20181,263
42Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profilingCancer Cell20021,238
43Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeuticsCancer Cell20021,233
44Nuclear factor-κBCancer Cell20041,227
45Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumorsCancer Cell20051,211
46Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote TumorigenesisCancer Cell20141,210
47Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemiaCancer Cell20021,208
48Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent MannerCancer Cell20101,204
49A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer GrowthCancer Cell20071,191
50Cancer-Secreted miR-105 Destroys Vascular Endothelial Barriers to Promote MetastasisCancer Cell20141,186