33.9(top 0.1%)
impact factor
2.5K(top 10%)
851.1K(top 1%)
517(top 0.1%)
34.2(top 0.1%)
extended IF
all documents
doc citations
882(top 0.1%)

Top Articles

1The blockade of immune checkpoints in cancer immunotherapyNature Reviews Cancer201210,874
2MicroRNA signatures in human cancersNature Reviews Cancer20067,008
3Oncomirs — microRNAs with a role in cancerNature Reviews Cancer20066,509
4Targeting HIF-1 for cancer therapyNature Reviews Cancer20036,111
5Epithelial–mesenchymal transitions in tumour progressionNature Reviews Cancer20025,923
6Photodynamic therapy for cancerNature Reviews Cancer20035,585
7The phosphatidylinositol 3-Kinase–AKT pathway in human cancerNature Reviews Cancer20025,480
8New functions for the matrix metalloproteinases in cancer progressionNature Reviews Cancer20025,365
9Multidrug resistance in cancer: role of ATP–dependent transportersNature Reviews Cancer20024,873
10Hypoxia — a key regulatory factor in tumour growthNature Reviews Cancer20024,590
11Why do cancers have high aerobic glycolysis?Nature Reviews Cancer20044,181
12Cancer nanomedicine: progress, challenges and opportunitiesNature Reviews Cancer20174,153
13Cancer nanotechnology: opportunities and challengesNature Reviews Cancer20054,111
14Regulation of cancer cell metabolismNature Reviews Cancer20114,100
155-Fluorouracil: mechanisms of action and clinical strategiesNature Reviews Cancer20034,015
16Fibroblasts in cancerNature Reviews Cancer20063,978
17The resurgence of platinum-based cancer chemotherapyNature Reviews Cancer20073,971
18The pathogenesis of cancer metastasis: the 'seed and soil' hypothesis revisitedNature Reviews Cancer20033,962
19The immune contexture in human tumours: impact on clinical outcomeNature Reviews Cancer20123,873
20Microtubules as a target for anticancer drugsNature Reviews Cancer20043,823
21Cancer drug resistance: an evolving paradigmNature Reviews Cancer20133,667
22STATs in cancer inflammation and immunity: a leading role for STAT3Nature Reviews Cancer20093,503
23The Bcl2 family: regulators of the cellular life-or-death switchNature Reviews Cancer20023,457
24Dissemination and growth of cancer cells in metastatic sitesNature Reviews Cancer20023,414
25Tumour stem cells and drug resistanceNature Reviews Cancer20053,360
26Papillomaviruses and cancer: from basic studies to clinical applicationNature Reviews Cancer20023,356
27Microenvironmental regulation of metastasisNature Reviews Cancer20093,157
28Overweight, obesity and cancer: epidemiological evidence and proposed mechanismsNature Reviews Cancer20043,092
29Cancer stem cells in solid tumours: accumulating evidence and unresolved questionsNature Reviews Cancer20083,070
30Cell cycle, CDKs and cancer: a changing paradigmNature Reviews Cancer20093,070
31Tumorigenesis and the angiogenic switchNature Reviews Cancer20033,059
32Integrins in cancer: biological implications and therapeutic opportunitiesNature Reviews Cancer20103,045
33Tumour-educated macrophages promote tumour progression and metastasisNature Reviews Cancer20042,971
34Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traitsNature Reviews Cancer20092,951
35ERBB receptors and cancer: the complexity of targeted inhibitorsNature Reviews Cancer20052,930
36Live or let die: the cell's response to p53Nature Reviews Cancer20022,906
37The biology and function of fibroblasts in cancerNature Reviews Cancer20162,886
38A census of human cancer genesNature Reviews Cancer20042,868
39Targeting RAS signalling pathways in cancer therapyNature Reviews Cancer20032,800
40Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?Nature Reviews Cancer20072,796
41Tumour-cell invasion and migration: diversity and escape mechanismsNature Reviews Cancer20032,757
42Epidermal growth factor receptor mutations in lung cancerNature Reviews Cancer20072,741
43Targeting hypoxia in cancer therapyNature Reviews Cancer20112,607
44Modes of resistance to anti-angiogenic therapyNature Reviews Cancer20082,603
45Otto Warburg's contributions to current concepts of cancer metabolismNature Reviews Cancer20112,566
46Cancer chemoprevention with dietary phytochemicalsNature Reviews Cancer20032,533
47Metastasis to bone: causes, consequences and therapeutic opportunitiesNature Reviews Cancer20022,498
48A decade of exploring the cancer epigenome — biological and translational implicationsNature Reviews Cancer20112,425
49Exploiting tumour hypoxia in cancer treatmentNature Reviews Cancer20042,406
50Cell-free nucleic acids as biomarkers in cancer patientsNature Reviews Cancer20112,372