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Top Articles

#TitleJournalYearCitations
1Are 90% of deaths from cancer caused by metastases?Cancer Medicine2019692
2Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced scienceCancer Medicine2019565
3β‐caryophyllene and β‐caryophyllene oxide—natural compounds of anticancer and analgesic propertiesCancer Medicine2016550
4Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapyCancer Medicine2018522
5Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosisCancer Medicine2017503
6Nrf2 in cancers: A double‐edged swordCancer Medicine2019370
7Microsatellite instability status determined by next‐generation sequencing and compared with PD‐L1 and tumor mutational burden in 11,348 patientsCancer Medicine2018348
8Role of tumor microenvironment in cancer progression and therapeutic strategyCancer Medicine2023324
9New prognostic factors and scoring system for patients with skeletal metastasisCancer Medicine2014322
10Ovarian cancer: Current status and strategies for improving therapeutic outcomesCancer Medicine2019312
11Iron overloaded polarizes macrophage to proinflammation phenotype through ROS/acetyl‐p53 pathwayCancer Medicine2018286
12PD‐1 as a potential target in cancer therapyCancer Medicine2013283
13Using adaptive magnetic resonance image‐guided radiation therapy for treatment of inoperable pancreatic cancerCancer Medicine2019278
14Interferon gamma in cancer immunotherapyCancer Medicine2018269
15Crosstalk between cancer and immune cells: Role of tumor‐associated macrophages in the tumor microenvironmentCancer Medicine2019260
16The precision prevention and therapy of HPV‐related cervical cancer: new concepts and clinical implicationsCancer Medicine2018244
17Sarcopenia and adverse health‐related outcomes: An umbrella review of meta‐analyses of observational studiesCancer Medicine2020244
18Metastatic patterns and survival outcomes in patients with stage IV colon cancer: A population‐based analysisCancer Medicine2020231
19Ipilimumab and radiation therapy for melanoma brain metastasesCancer Medicine2013213
20Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC 1Cancer Medicine2012208
21Therapeutic bacteria to combat cancer; current advances, challenges, and opportunitiesCancer Medicine2019208
22Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K‐Akt signaling in gastric cancerCancer Medicine2019207
23Adherence to Mediterranean diet and risk of cancer: an updated systematic review and meta‐analysis of observational studiesCancer Medicine2015205
24Vessel co‐option in primary human tumors and metastases: an obstacle to effective anti‐angiogenic treatment?Cancer Medicine2013197
25Lenvatinib inhibits angiogenesis and tumor fibroblast growth factor signaling pathways in human hepatocellular carcinoma modelsCancer Medicine2018196
26Cancer survival disparities by health insurance statusCancer Medicine2013195
27Response rates and durability of chemotherapy among 62 patients with metastatic Merkel cell carcinomaCancer Medicine2016192
28Depression and prostate cancer risk: A Mendelian randomization studyCancer Medicine2020192
29RGD peptide in cancer targeting: Benefits, challenges, solutions, and possible integrin–RGD interactionsCancer Medicine2024192
30BAY 87‐2243, a highly potent and selective inhibitor of hypoxia‐induced gene activation has antitumor activities by inhibition of mitochondrial complex ICancer Medicine2013189
31Global circular RNA expression profile of human gastric cancer and its clinical significanceCancer Medicine2017189
32Cancer‐associated fibroblasts promote M2 polarization of macrophages in pancreatic ductal adenocarcinomaCancer Medicine2017172
33Overexpression of Snail induces epithelial–mesenchymal transition and a cancer stem cell–like phenotype in human colorectal cancer cellsCancer Medicine2012168
34A novel plasma circular RNA circFARSA is a potential biomarker for non‐small cell lung cancerCancer Medicine2018164
35Study and analysis of antitumor resistance mechanism of PD1/PD‐L1 immune checkpoint blockerCancer Medicine2020164
36LncRNA UCA1 promotes proliferation and cisplatin resistance of oral squamous cell carcinoma by sunppressing miR‐184 expressionCancer Medicine2017162
37Anti‐PD‐1 therapy redirects macrophages from an M2 to an M1 phenotype inducing regression of OS lung metastasesCancer Medicine2018156
38MicroRNAs in glioblastoma multiforme pathogenesis and therapeuticsCancer Medicine2016152
39Quercetin shows anti‐tumor effect in hepatocellular carcinoma LM3 cells by abrogating JAK2/STAT3 signaling pathwayCancer Medicine2019152
40The role of laser interstitial thermal therapy in enhancing progression‐free survival of difficult‐to‐access high‐grade gliomas: a multicenter studyCancer Medicine2014147
41Disparities in cancer outcomes across age, sex, and race/ethnicity among patients with pancreatic cancerCancer Medicine2018146
42Automated home monitoring and management of patient‐reported symptoms during chemotherapy: results of the symptom care at home RCTCancer Medicine2017143
43Profiles of immune infiltration in colorectal cancer and their clinical significant: A gene expression‐based studyCancer Medicine2018142
44Changing trends in the disease burden of esophageal cancer in China from 1990 to 2017 and its predicted level in 25 yearsCancer Medicine2021142
45Symptom clusters experienced by breast cancer patients at various treatment stages: A systematic reviewCancer Medicine2021141
46U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cellsCancer Medicine2014139
47Integrating natural compounds and nanoparticle‐based drug delivery systems: A novel strategy for enhanced efficacy and selectivity in cancer therapyCancer Medicine2024137
48Gene panel testing of 5589 BRCA1/2‐negative index patients with breast cancer in a routine diagnostic setting: results of the German Consortium for Hereditary Breast and Ovarian CancerCancer Medicine2018135
49Lean body mass as an independent determinant of dose‐limiting toxicity and neuropathy in patients with colon cancer treated with FOLFOX regimensCancer Medicine2016134
50HuR‐regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancerCancer Medicine2016133