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Top Articles

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2Traditional Chinese medicine as a cancer treatment: Modern perspectives of ancient but advanced scienceCancer Medicine2019461
3β‐caryophyllene and β‐caryophyllene oxide—natural compounds of anticancer and analgesic propertiesCancer Medicine2016415
4Common oral complications of head and neck cancer radiation therapy: mucositis, infections, saliva change, fibrosis, sensory dysfunctions, dental caries, periodontal disease, and osteoradionecrosisCancer Medicine2017400
5Lactate dehydrogenase A: A key player in carcinogenesis and potential target in cancer therapyCancer Medicine2018371
6PD‐1 as a potential target in cancer therapyCancer Medicine2013369
7Microsatellite instability status determined by next‐generation sequencing and compared with PD‐L1 and tumor mutational burden in 11,348 patientsCancer Medicine2018348
8Nrf2 in cancers: A double‐edged swordCancer Medicine2019289
9New prognostic factors and scoring system for patients with skeletal metastasisCancer Medicine2014282
10Ipilimumab and radiation therapy for melanoma brain metastasesCancer Medicine2013256
11Using adaptive magnetic resonance image‐guided radiation therapy for treatment of inoperable pancreatic cancerCancer Medicine2019243
12Interferon gamma in cancer immunotherapyCancer Medicine2018240
13Vessel co‐option in primary human tumors and metastases: an obstacle to effective anti‐angiogenic treatment?Cancer Medicine2013231
14Adherence to Mediterranean diet and risk of cancer: an updated systematic review and meta‐analysis of observational studiesCancer Medicine2015228
15Global circular RNA expression profile of human gastric cancer and its clinical significanceCancer Medicine2017218
16Crosstalk between cancer and immune cells: Role of tumor‐associated macrophages in the tumor microenvironmentCancer Medicine2019211
17Nisin, an apoptogenic bacteriocin and food preservative, attenuates HNSCC tumorigenesis via CHAC1Cancer Medicine2012210
18Response rates and durability of chemotherapy among 62 patients with metastatic Merkel cell carcinomaCancer Medicine2016203
19Reduced m6A modification predicts malignant phenotypes and augmented Wnt/PI3K‐Akt signaling in gastric cancerCancer Medicine2019201
20BAY 87‐2243, a highly potent and selective inhibitor of hypoxia‐induced gene activation has antitumor activities by inhibition of mitochondrial complex ICancer Medicine2013197
21Ovarian cancer: Current status and strategies for improving therapeutic outcomesCancer Medicine2019197
22Projections of cancer incidence and cancer‐related deaths in Germany by 2020 and 2030Cancer Medicine2016195
23The precision prevention and therapy of HPV‐related cervical cancer: new concepts and clinical implicationsCancer Medicine2018194
24Profiles of immune infiltration in colorectal cancer and their clinical significant: A gene expression‐based studyCancer Medicine2018194
25Therapeutic bacteria to combat cancer; current advances, challenges, and opportunitiesCancer Medicine2019191
26Overexpression of Snail induces epithelial–mesenchymal transition and a cancer stem cell–like phenotype in human colorectal cancer cellsCancer Medicine2012190
27Cancer survival disparities by health insurance statusCancer Medicine2013190
28The role of laser interstitial thermal therapy in enhancing progression‐free survival of difficult‐to‐access high‐grade gliomas: a multicenter studyCancer Medicine2014188
29Iron overloaded polarizes macrophage to proinflammation phenotype through ROS/acetyl‐p53 pathwayCancer Medicine2018171
30LncRNA UCA1 promotes proliferation and cisplatin resistance of oral squamous cell carcinoma by sunppressing miR‐184 expressionCancer Medicine2017170
31A novel plasma circular RNA circFARSA is a potential biomarker for non‐small cell lung cancerCancer Medicine2018167
32Lenvatinib inhibits angiogenesis and tumor fibroblast growth factor signaling pathways in human hepatocellular carcinoma modelsCancer Medicine2018163
33HuR‐regulated lncRNA NEAT1 stability in tumorigenesis and progression of ovarian cancerCancer Medicine2016155
34Automated home monitoring and management of patient‐reported symptoms during chemotherapy: results of the symptom care at home RCTCancer Medicine2017153
35MicroRNAs in glioblastoma multiforme pathogenesis and therapeuticsCancer Medicine2016152
36Metastatic patterns and survival outcomes in patients with stage IV colon cancer: A population‐based analysisCancer Medicine2020150
37Medical management of gastric cancer: a 2017 updateCancer Medicine2018145
38Sarcopenia and adverse health‐related outcomes: An umbrella review of meta‐analyses of observational studiesCancer Medicine2020139
39Disparities in cancer outcomes across age, sex, and race/ethnicity among patients with pancreatic cancerCancer Medicine2018136
40Cancer‐associated fibroblasts promote M2 polarization of macrophages in pancreatic ductal adenocarcinomaCancer Medicine2017135
41Overexpression of the microRNA miR‐433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cellsCancer Medicine2015132
42Prognostic factor of lenvatinib for unresectable hepatocellular carcinoma in real‐world conditions—Multicenter analysisCancer Medicine2019131
43Long noncoding RNA HOTAIR is relevant to cellular proliferation, invasiveness, and clinical relapse in small‐cell lung cancerCancer Medicine2014130
44Evaluation of a prognostic model for risk of relapse in stage I seminoma surveillanceCancer Medicine2015129
45U‐251 revisited: genetic drift and phenotypic consequences of long‐term cultures of glioblastoma cellsCancer Medicine2014127
46Targeting hyperactivation of the AKT survival pathway to overcome therapy resistance of melanoma brain metastasesCancer Medicine2013126
47Gene panel testing of 5589 BRCA1/2‐negative index patients with breast cancer in a routine diagnostic setting: results of the German Consortium for Hereditary Breast and Ovarian CancerCancer Medicine2018126
48Anti‐PD‐1 therapy redirects macrophages from an M2 to an M1 phenotype inducing regression of OS lung metastasesCancer Medicine2018126
49A systematic review of microRNA expression profiling studies in human gastric cancerCancer Medicine2014125
50Antiproliferative and metabolic effects of metformin in a preoperative window clinical trial for endometrial cancerCancer Medicine2015124