11.7(top 1%)
Impact Factor
12.2(top 1%)
extended IF
244(top 1%)
H-Index
5.4K
authors
2.8K
papers
249.6K
citations
6.3K
citing journals
153K
citing authors

Most Cited Articles of Nature Chemical Biology

TitleYearCitations
Network pharmacology: the next paradigm in drug discovery20082.3K
N6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO20111.9K
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury20051.9K
Reconciling the chemistry and biology of reactive oxygen species20081.6K
Networking by small-molecule hormones in plant immunity20091.6K
A METTL3-METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation20141.5K
The role of dynamic conformational ensembles in biomolecular recognition20091.4K
Identification of RIP1 kinase as a specific cellular target of necrostatins20081.4K
Mass spectrometry-based proteomics turns quantitative20051.3K
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli20091.2K
The function of terpene natural products in the natural world20071.2K
Chemistry and biology of reactive oxygen species in signaling or stress responses20111.1K
Chemistry in living systems20051.1K
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer20091.1K
The role of iron and reactive oxygen species in cell death20141.1K
Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors2005951
Synthetic fluorescent sensors for studying the cell biology of metals2008934
Targeting virulence: a new paradigm for antimicrobial therapy2007920
ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition2017908
Targeting mitochondria metabolism for cancer therapy2015858
RNAi therapeutics: a potential new class of pharmaceutical drugs2006857
Rational design of inhibitors that bind to inactive kinase conformations2006854
Metabolic engineering of Escherichia coli for direct production of 1,4-butanediol2011835
Mechanisms for copper acquisition, distribution and regulation2008826
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism2008825