13.9(top 1%)
Impact Factor
14.9(top 1%)
extended IF
149(top 2%)
H-Index
authors
1.8K
papers
103.4K
citations
citing journals
citing authors

Most Cited Articles of Pharmacology & Therapeutics

TitleYearCitations
Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation20132.1K
Glycogen synthase kinase-3 (GSK3): regulation, actions, and diseases2015821
Immune system to brain signaling: neuropsychopharmacological implications2011741
Cardiac fibroblasts: at the heart of myocardial remodeling2009734
Structure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive review2013604
Molecular distinction between physiological and pathological cardiac hypertrophy: experimental findings and therapeutic strategies2010556
Exosomes: Therapy delivery tools and biomarkers of diseases2017524
Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway2014520
The pharmacology of sigma-1 receptors2009504
GDNF, NGF and BDNF as therapeutic options for neurodegeneration2013468
Three-dimensional culture systems in cancer research: Focus on tumor spheroid model2016441
Targeting the TGFβ pathway for cancer therapy2015431
Chemokines, neuronal-glial interactions, and central processing of neuropathic pain2010429
The dynamic effects of nicotine on the developing brain2009405
Animal models of cognitive dysfunction and negative symptoms of schizophrenia: focus on NMDA receptor antagonism2010402
Excessive discounting of delayed reinforcers as a trans-disease process contributing to addiction and other disease-related vulnerabilities: emerging evidence2012395
Circular RNA and its mechanisms in disease: From the bench to the clinic2018382
Glioblastoma multiforme: Pathogenesis and treatment2015370
Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer2016363
ATM and ATR as therapeutic targets in cancer2015361
Nicotinic acetylcholine receptors: from basic science to therapeutics2013358
Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways2014354
Insulin in the brain: there and back again2012340
Targeting interleukin-6 in inflammatory autoimmune diseases and cancers2014333
Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits2014329