| 1 | Role of interleukin-6 in cancer progression and therapeutic resistance | Tumor Biology | 2016 | 925 |
| 2 | Progress in the treatment of advanced gastric cancer | Tumor Biology | 2017 | 786 |
| 3 | Radiation-induced cell death mechanisms | Tumor Biology | 2010 | 578 |
| 4 | Collagen as a double-edged sword in tumor progression | Tumor Biology | 2013 | 518 |
| 5 | Major apoptotic mechanisms and genes involved in apoptosis | Tumor Biology | 2016 | 516 |
| 6 | Plasma long noncoding RNA protected by exosomes as a potential stable biomarker for gastric cancer | Tumor Biology | 2014 | 371 |
| 7 | Long noncoding RNA: an emerging paradigm of cancer research | Tumor Biology | 2013 | 354 |
| 8 | Matrix metalloproteinases in cancer: their value as diagnostic and prognostic markers and therapeutic targets | Tumor Biology | 2013 | 331 |
| 9 | Investigation of miR-21, miR-141, and miR-221 in blood circulation of patients with prostate cancer | Tumor Biology | 2011 | 311 |
| 10 | MALAT1 promotes the proliferation and metastasis of osteosarcoma cells by activating the PI3K/Akt pathway | Tumor Biology | 2014 | 291 |
| 11 | Downregulated long noncoding RNA MEG3 is associated with poor prognosis and promotes cell proliferation in gastric cancer | Tumor Biology | 2013 | 275 |
| 12 | H19 promotes pancreatic cancer metastasis by derepressing let-7’s suppression on its target HMGA2-mediated EMT | Tumor Biology | 2014 | 269 |
| 13 | Epithelial to mesenchymal transition inducing transcription factors and metastatic cancer | Tumor Biology | 2014 | 239 |
| 14 | The role of oxidative stress on breast cancer development and therapy | Tumor Biology | 2016 | 237 |
| 15 | An overview of targeted alpha therapy | Tumor Biology | 2011 | 236 |
| 16 | Exosomes mediate drug resistance transfer in MCF-7 breast cancer cells and a probable mechanism is delivery of P-glycoprotein | Tumor Biology | 2014 | 235 |
| 17 | C-Myc-activated long noncoding RNA CCAT1 promotes colon cancer cell proliferation and invasion | Tumor Biology | 2014 | 215 |
| 18 | Anti-tumor activities of matrine and oxymatrine: literature review | Tumor Biology | 2014 | 208 |
| 19 | Upregulation of long non-coding RNA MALAT1 correlates with tumor progression and poor prognosis in clear cell renal cell carcinoma | Tumor Biology | 2014 | 201 |
| 20 | Molecular targets of curcumin for cancer therapy: an updated review | Tumor Biology | 2016 | 194 |
| 21 | The cancer stem cell niche: cross talk between cancer stem cells and their microenvironment | Tumor Biology | 2014 | 193 |
| 22 | The role of gut microbiota in the pathogenesis of colorectal cancer | Tumor Biology | 2013 | 190 |
| 23 | Serum miR-21 and miR-92a as biomarkers in the diagnosis and prognosis of colorectal cancer | Tumor Biology | 2013 | 189 |
| 24 | Twist: a molecular target in cancer therapeutics | Tumor Biology | 2013 | 189 |
| 25 | LncRNAs: key players and novel insights into cervical cancer | Tumor Biology | 2015 | 187 |
| 26 | High serum levels of extracellular vesicles expressing malignancy-related markers are released in patients with various types of hematological neoplastic disorders | Tumor Biology | 2015 | 183 |
| 27 | EarlyCDT®-Lung test: improved clinical utility through additional autoantibody assays | Tumor Biology | 2012 | 182 |
| 28 | Lactate dehydrogenase A is overexpressed in pancreatic cancer and promotes the growth of pancreatic cancer cells | Tumor Biology | 2013 | 180 |
| 29 | CCAT2 is a lung adenocarcinoma-specific long non-coding RNA and promotes invasion of non-small cell lung cancer | Tumor Biology | 2014 | 180 |
| 30 | Overexpression of long non-coding RNA MALAT1 is correlated with clinical progression and unfavorable prognosis in pancreatic cancer | Tumor Biology | 2014 | 177 |
| 31 | Epigenetics and cervical cancer: from pathogenesis to therapy | Tumor Biology | 2014 | 175 |
| 32 | The growth arrest-specific transcript 5 (GAS5): a pivotal tumor suppressor long noncoding RNA in human cancers | Tumor Biology | 2015 | 173 |
| 33 | Oncocers: ceRNA-mediated cross-talk by sponging miRNAs in oncogenic pathways | Tumor Biology | 2015 | 172 |
| 34 | Exosomes derived from gastric cancer cells activate NF-κB pathway in macrophages to promote cancer progression | Tumor Biology | 2016 | 171 |
| 35 | HE4: a new potential early biomarker for the recurrence of ovarian cancer | Tumor Biology | 2010 | 168 |
| 36 | The role of TWIST1 in epithelial-mesenchymal transition and cancers | Tumor Biology | 2015 | 168 |
| 37 | Decreased expression of long noncoding RNA MEG3 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer | Tumor Biology | 2015 | 164 |
| 38 | Long noncoding RNA MALAT1 associates with the malignant status and poor prognosis in glioma | Tumor Biology | 2015 | 164 |
| 39 | High intratumoral expression of fibroblast activation protein (FAP) in colon cancer is associated with poorer patient prognosis | Tumor Biology | 2013 | 162 |
| 40 | Increased expression of long intergenic non-coding RNA LINC00152 in gastric cancer and its clinical significance | Tumor Biology | 2014 | 161 |
| 41 | Association of well-characterized lung cancer lncRNA polymorphisms with lung cancer susceptibility and platinum-based chemotherapy response | Tumor Biology | 2016 | 161 |
| 42 | The M2 phenotype of tumor-associated macrophages in the stroma confers a poor prognosis in pancreatic cancer | Tumor Biology | 2016 | 159 |
| 43 | SIRT5 facilitates cancer cell growth and drug resistance in non-small cell lung cancer | Tumor Biology | 2014 | 158 |
| 44 | The level of circulating miRNA-10b and miRNA-373 in detecting lymph node metastasis of breast cancer: potential biomarkers | Tumor Biology | 2012 | 157 |
| 45 | Long noncoding RNA NEAT1 promotes glioma pathogenesis by regulating miR-449b-5p/c-Met axis | Tumor Biology | 2015 | 156 |
| 46 | Long non-coding RNA MALAT1 modulates radiosensitivity of HR-HPV+ cervical cancer via sponging miR-145 | Tumor Biology | 2015 | 151 |
| 47 | Long noncoding RNA GAS5 suppresses the migration and invasion of hepatocellular carcinoma cells via miR-21 | Tumor Biology | 2015 | 148 |
| 48 | HE4 a novel tumour marker for ovarian cancer: comparison with CA 125 and ROMA algorithm in patients with gynaecological diseases | Tumor Biology | 2011 | 147 |
| 49 | MicroRNAs in osteosarcoma: diagnostic and therapeutic aspects | Tumor Biology | 2013 | 147 |
| 50 | Altered expression of SIRT gene family in head and neck squamous cell carcinoma | Tumor Biology | 2013 | 147 |