3.5(top 4%)
Impact Factor
3.7(top 4%)
extended IF
125(top 2%)
H-Index
3.9K
authors
8.8K
papers
199.9K
citations
6.6K
citing journals
77K
citing authors

Most Cited Articles of Cancer Chemotherapy and Pharmacology

TitleYearCitations
Determination of subcutaneous tumor size in athymic (nude) mice19891.2K
Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients2000550
Matrix metalloproteinases and metastasis1999526
Preclinical pharmacologic evaluation of geldanamycin as an antitumor agent1995442
The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin1998434
Platinum-based drugs: past, present and future2016422
Early clinical studies with cis-diammine-1,1-cyclobutane dicarboxylate platinum II1982417
Multidrug resistance: molecular mechanisms and clinical relevance1997416
Relationship between exposure to sunitinib and efficacy and tolerability endpoints in patients with cancer: results of a pharmacokinetic/pharmacodynamic meta-analysis2010380
Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft models2007372
Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats2011358
Ruthenium-based chemotherapeutics: are they ready for prime time?2010358
Pharmacokinetics of busulfan: correlation with veno-occlusive disease in patients undergoing bone marrow transplantation1989336
Cancer and the tumor microenvironment: a review of an essential relationship2009328
The effect of antimicrotubule agents on signal transduction pathways of apoptosis: a review1999325
Overcoming acquired resistance to anticancer therapy: focus on the PI3K/AKT/mTOR pathway2013314
Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity2004309
Efficacy of topoisomerase I inhibitors, topotecan and irinotecan, administered at low dose levels in protracted schedules to mice bearing xenografts of human tumors1995302
A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer2011294
Phase I study of oxaliplatin in patients with advanced cancer1990281
Clinical pharmacokinetics of bevacizumab in patients with solid tumors2008270
A phase I dose-escalation trial of 2-deoxy-D-glucose alone or combined with docetaxel in patients with advanced solid tumors2013268
Comparison of systemic availability of curcumin with that of curcumin formulated with phosphatidylcholine2007263
Marqibo® (vincristine sulfate liposome injection) improves the pharmacokinetics and pharmacodynamics of vincristine2013261
Advances in ovarian cancer therapy2018257