# | Title | Journal | Year | Citations |
---|
|
1 | Bioactive Microbial Metabolites | Journal of Antibiotics | 2005 | 2,620 |
2 | Rapamycin (AY-22,989), a new antifungal antibiotic. I. Taxonomy of the producing streptomycete and isolation of the active principle. | Journal of Antibiotics | 1975 | 1,348 |
3 | FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics. | Journal of Antibiotics | 1987 | 1,139 |
4 | FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. | Journal of Antibiotics | 1987 | 1,018 |
5 | ML-236A, ML-236B, and ML-236C, new inhibitors of cholesterogensis produced by Penicillium citrinum. | Journal of Antibiotics | 1976 | 882 |
6 | Thoughts and facts about antibiotics: Where we are now and where we are heading | Journal of Antibiotics | 2012 | 858 |
7 | Rapamycin (AY-22,989), a new antifungal antibiotic. II. Fermentation, isolation and characterization. | Journal of Antibiotics | 1975 | 849 |
8 | Microbial drug discovery: 80 years of progress | Journal of Antibiotics | 2009 | 818 |
9 | Bestatin, an inhibitor of aminopeptidase B, produced by actinomycetes. | Journal of Antibiotics | 1976 | 707 |
10 | PEPSTATIN, A NEW PEPSIN INHIBITOR PRODUCED BY AGTINOMYGETES | Journal of Antibiotics | 1970 | 685 |
11 | A new alkaloid AM-2282 of Streptomyces origin taxonomy, fermentation, isolation and preliminary characterization. | Journal of Antibiotics | 1977 | 638 |
12 | Monacolin K, a new hypocholesterolemic agent produced by a Monascus species. | Journal of Antibiotics | 1979 | 626 |
13 | Epothilons A and B: Antifungal and Cytotoxic Compounds from Sorangium cellulosum (Myxobacteria). Production, Physico-chemical and Biological Properties. | Journal of Antibiotics | 1996 | 612 |
14 | TUNICAMYCIN, A NEW ANTIBIOTIC. I | Journal of Antibiotics | 1971 | 560 |
15 | Fungal metabolites. Part 11. A potent immunosuppressive activity found in Isaria sinclairii metabolite. | Journal of Antibiotics | 1994 | 524 |
16 | Lactacystin, a novel microbial metabolite, induces neuritogenesis of neuroblastoma cells. | Journal of Antibiotics | 1991 | 519 |
17 | Thienamycin, a new .BETA.-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties. | Journal of Antibiotics | 1979 | 494 |
18 | Fengycin - A novel antifungal lipopeptide antibiotic produced by Bacillus subtilis F-29-3. | Journal of Antibiotics | 1986 | 476 |
19 | GELDANAMYCIN, A NEW ANTIBIOTIC | Journal of Antibiotics | 1970 | 465 |
20 | FR901228, a novel antitumor bicyclic depsipeptide produced by chromobacterium violaceum No. 968. I. Taxonomy, fermentation, isolation, physico-chemical and biological properties, and antitumor activity. | Journal of Antibiotics | 1994 | 423 |
21 | Antimicrobial action of .EPSILON.-poly-L-lysine. | Journal of Antibiotics | 1984 | 412 |
22 | Naturally-occurring .BETA.-lactamase inhibitors with antibacterial activity. | Journal of Antibiotics | 1976 | 387 |
23 | Antibiotics in the clinical pipeline in 2013 | Journal of Antibiotics | 2013 | 354 |
24 | The antibiotic resistance crisis, with a focus on the United States | Journal of Antibiotics | 2017 | 347 |
25 | A new antifungal antibiotic, trichostatin. | Journal of Antibiotics | 1976 | 335 |
26 | K-252a, a potent inhibitor of protein kinase C from microbial origin. | Journal of Antibiotics | 1986 | 325 |
27 | Prospects for new antibiotics: a molecule-centered perspective | Journal of Antibiotics | 2014 | 318 |
28 | Activity of rapamycin (AY-22,989) against transplanted tumors. | Journal of Antibiotics | 1984 | 313 |
29 | Resistance to rifampicin: a review | Journal of Antibiotics | 2014 | 313 |
30 | Metabolic products of microorganisms. 224. Bafilomycins, a new group of macrolide antibiotics. Production, isolation, chemical structure and biological activity. | Journal of Antibiotics | 1984 | 309 |
31 | Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini. I. Producing organism, fermentation, isolation and biological activity. | Journal of Antibiotics | 1987 | 304 |
32 | ON THE MECHANISM OF ACTION OF BLEOMYCIN : SCISSION OF DNA STRANDS IN VITRO AND IN VIVO | Journal of Antibiotics | 1969 | 302 |
33 | Dynemicin A, a novel antibiotic with the anthraquinone and 1,5-diyn-3-ene subunit. | Journal of Antibiotics | 1989 | 302 |
34 | Spirotryprostatin B, a Novel Mammalian Cell Cycle Inhibitor Produced by Aspergillus fumigatus. | Journal of Antibiotics | 1996 | 301 |
35 | Antibiotics in the clinical pipeline at the end of 2015 | Journal of Antibiotics | 2017 | 298 |
36 | BB-K8, A NEW SEMISYNTHETIC AMINOGLYCOSIDE ANTIBIOTIC | Journal of Antibiotics | 1972 | 297 |
37 | Nucleoside antibiotics: Structure, biological activity, and biosynthesis. | Journal of Antibiotics | 1988 | 290 |
38 | Structure of lactacystin, a new microbial metabolite which induces differentiation of neuroblastoma cells. | Journal of Antibiotics | 1991 | 286 |
39 | Cyanobacteria: an emerging source for drug discovery | Journal of Antibiotics | 2011 | 279 |
40 | TMC-95A, B, C, and D, Novel Proteasome Inhibitors Produced by Apiospora montagnei Sacc. TC 1093. Taxonomy, Production, Isolation, and Biological Activities. | Journal of Antibiotics | 2000 | 278 |
41 | Abyssomicins, Inhibitors of the para-Aminobenzoic Acid Pathway Produced by the Marine Verrucosispora Strain AB-18-032 | Journal of Antibiotics | 2004 | 273 |
42 | Ivermectin: a systematic review from antiviral effects to COVID-19 complementary regimen | Journal of Antibiotics | 2020 | 269 |
43 | The spinosyn family of insecticides: realizing the potential of natural products research | Journal of Antibiotics | 2010 | 268 |
44 | CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism. | Journal of Antibiotics | 1978 | 266 |
45 | Studies on bredinin. I. Isolation, characterization and biological properties. | Journal of Antibiotics | 1974 | 264 |
46 | LEUPEPTINS, NEW PROTEASE INHIBITORS FROM ACTINOMYCETES | Journal of Antibiotics | 1969 | 263 |
47 | Studies on neplanocin a, new antitumor antibiotic. I. Producing organism, isolation and characterization. | Journal of Antibiotics | 1981 | 261 |
48 | Romidepsin (Istodax, NSC 630176, FR901228, FK228, depsipeptide): a natural product recently approved for cutaneous T-cell lymphoma | Journal of Antibiotics | 2011 | 257 |
49 | Salinomycin, a new polyether antibiotic. | Journal of Antibiotics | 1974 | 253 |
50 | Staurosporine inhibits tyrosine-specific protein kinase activity of Rous sarcoma virus transforming protein p60. | Journal of Antibiotics | 1987 | 252 |