6.1(top 2%)
Impact Factor
6.6(top 2%)
extended IF
223(top 1%)
H-Index
3.3K
authors
13.1K
papers
462.9K
citations
10.5K
citing journals
104.5K
citing authors

Most Cited Articles of Clinical Pharmacology and Therapeutics

TitleYearCitations
A method for estimating the probability of adverse drug reactions19818K
Biomarkers and surrogate endpoints: preferred definitions and conceptual framework20014.2K
Nanoparticles in medicine: therapeutic applications and developments20081.8K
Commentary: a physiological approach to hepatic drug clearance19751.5K
Pharmacogenomics knowledge for personalized medicine20121.2K
Clinical biostatistics. LIV. The biostatistics of concordance1981917
Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine1979851
Identification of functionally variant MDR1 alleles among European Americans and African Americans2001773
Monoclonal antibody pharmacokinetics and pharmacodynamics2008740
Physiologic, subjective, and behavioral effects of amphetamine, methamphetamine, ephedrine, phenmetrazine, and methylphenidate in man1971718
Concentrations of tramadol and O-desmethyltramadol enantiomers in different CYP2D6 genotypes2007697
Pharmacogenetics: from bench to byte--an update of guidelines2011684
CPIC: Clinical Pharmacogenetics Implementation Consortium of the Pharmacogenomics Research Network2011670
Polymorphisms in human MDR1 (P-glycoprotein): recent advances and clinical relevance2004659
Use of pharmacogenetic and clinical factors to predict the therapeutic dose of warfarin2008643
Development of a large-scale de-identified DNA biobank to enable personalized medicine2008627
Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update2013617
Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine1997601
Minimization: a new method of assigning patients to treatment and control groups1974596
Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance2006579
Case definition and phenotype standardization in drug-induced liver injury2011563
Trends in risks associated with new drug development: success rates for investigational drugs2010563
Changes in plasma protein binding have little clinical relevance2002562
Clinical pharmacology of buprenorphine: ceiling effects at high doses1994560
Biodistribution of 89Zr-trastuzumab and PET imaging of HER2-positive lesions in patients with metastatic breast cancer2010553