| 1 | Colorimetric Method for Determination of Sugars and Related Substances | Analytical Chemistry | 1956 | 44,061 |
| 2 | Use of Dinitrosalicylic Acid Reagent for Determination of Reducing Sugar | Analytical Chemistry | 1959 | 23,034 |
| 3 | Smoothing and Differentiation of Data by Simplified Least Squares Procedures. | Analytical Chemistry | 1964 | 16,256 |
| 4 | Reaction Kinetics in Differential Thermal Analysis | Analytical Chemistry | 1957 | 11,601 |
| 5 | Sequential extraction procedure for the speciation of particulate trace metals | Analytical Chemistry | 1979 | 9,446 |
| 6 | Automatic Recording Apparatus for Use in Chromatography of Amino Acids | Analytical Chemistry | 1958 | 8,870 |
| 7 | Official Methods of Analysis of | Analytical Chemistry | 1980 | 7,775 |
| 8 | Mass Spectrometric Sequencing of Proteins from Silver-Stained Polyacrylamide Gels | Analytical Chemistry | 1996 | 7,587 |
| 9 | Microdetermination of Phosphorus | Analytical Chemistry | 1956 | 6,761 |
| 10 | Strategies for the Assessment of Matrix Effect in Quantitative Bioanalytical Methods Based on HPLC−MS/MS | Analytical Chemistry | 2003 | 4,678 |
| 11 | Theory of Stationary Electrode Polarography. Single Scan and Cyclic Methods Applied to Reversible, Irreversible, and Kinetic Systems. | Analytical Chemistry | 1964 | 4,596 |
| 12 | Solid phase microextraction with thermal desorption using fused silica optical fibers | Analytical Chemistry | 1990 | 4,093 |
| 13 | Laser desorption ionization of proteins with molecular masses exceeding 10,000 daltons | Analytical Chemistry | 1988 | 4,057 |
| 14 | Ferrozine---a new spectrophotometric reagent for iron | Analytical Chemistry | 1970 | 3,910 |
| 15 | Rapid Prototyping of Microfluidic Systems in Poly(dimethylsiloxane) | Analytical Chemistry | 1998 | 3,901 |
| 16 | XCMS: Processing Mass Spectrometry Data for Metabolite Profiling Using Nonlinear Peak Alignment, Matching, and Identification | Analytical Chemistry | 2006 | 3,852 |
| 17 | Empirical Statistical Model To Estimate the Accuracy of Peptide Identifications Made by MS/MS and Database Search | Analytical Chemistry | 2002 | 3,831 |
| 18 | A Statistical Model for Identifying Proteins by Tandem Mass Spectrometry | Analytical Chemistry | 2003 | 3,804 |
| 19 | Limits for qualitative detection and quantitative determination. Application to radiochemistry | Analytical Chemistry | 1968 | 3,755 |
| 20 | Phenol-hypochlorite reaction for determination of ammonia | Analytical Chemistry | 1967 | 3,457 |
| 21 | Determination of Size and Concentration of Gold Nanoparticles from UV−Vis Spectra | Analytical Chemistry | 2007 | 3,064 |
| 22 | Theory and Application of Cyclic Voltammetry for Measurement of Electrode Reaction Kinetics. | Analytical Chemistry | 1965 | 3,009 |
| 23 | AGREE—Analytical GREEnness Metric Approach and Software | Analytical Chemistry | 2020 | 2,832 |
| 24 | Preparation and Characterization of Au Colloid Monolayers | Analytical Chemistry | 1995 | 2,442 |
| 25 | Partial least-squares methods for spectral analyses. 1. Relation to other quantitative calibration methods and the extraction of qualitative information | Analytical Chemistry | 1988 | 2,172 |
| 26 | A New Analysis of Thermogravimetric Traces. | Analytical Chemistry | 1963 | 2,080 |
| 27 | Rapid Preparation of Fatty Acid Esters from Lipids for Gas Chromatographic Analysis. | Analytical Chemistry | 1966 | 2,069 |
| 28 | High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number | Analytical Chemistry | 2011 | 2,062 |
| 29 | Solvent Compatibility of Poly(dimethylsiloxane)-Based Microfluidic Devices | Analytical Chemistry | 2003 | 2,052 |
| 30 | Stop and Go Extraction Tips for Matrix-Assisted Laser Desorption/Ionization, Nanoelectrospray, and LC/MS Sample Pretreatment in Proteomics | Analytical Chemistry | 2003 | 1,985 |
| 31 | Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions | Analytical Chemistry | 2005 | 1,935 |
| 32 | A Model for Random Sampling and Estimation of Relative Protein Abundance in Shotgun Proteomics | Analytical Chemistry | 2004 | 1,894 |
| 33 | Chromatography of Amino Acids on Sulfonated Polystyrene Resins. An Improved System | Analytical Chemistry | 1958 | 1,876 |
| 34 | Zone electrophoresis in open-tubular glass capillaries | Analytical Chemistry | 1981 | 1,790 |
| 35 | Quantitative Analysis of Anatase-Rutile Mixtures with an X-Ray Diffractometer | Analytical Chemistry | 1957 | 1,721 |
| 36 | X-ray photoelectron studies on some oxides and hydroxides of cobalt, nickel, and copper | Analytical Chemistry | 1975 | 1,699 |
| 37 | The Rapid Preparation of Fatty Acid Esters for Gas Chromatographic Analysis | Analytical Chemistry | 1961 | 1,685 |
| 38 | Electrokinetic separations with micellar solutions and open-tubular capillaries | Analytical Chemistry | 1984 | 1,679 |
| 39 | Micro Total Analysis Systems. 1. Introduction, Theory, and Technology | Analytical Chemistry | 2002 | 1,671 |
| 40 | Tandem Mass Tags: A Novel Quantification Strategy for Comparative Analysis of Complex Protein Mixtures by MS/MS | Analytical Chemistry | 2003 | 1,666 |
| 41 | Molecular Imaging of Biological Samples: Localization of Peptides and Proteins Using MALDI-TOF MS | Analytical Chemistry | 1997 | 1,649 |
| 42 | Field-Deployable, High-Resolution, Time-of-Flight Aerosol Mass Spectrometer | Analytical Chemistry | 2006 | 1,633 |
| 43 | X-ray photoelectron spectroscopic studies of iron oxides | Analytical Chemistry | 1977 | 1,632 |
| 44 | High performance liquid chromatographic determination of subpicomole amounts of amino acids by precolumn fluorescence derivatization with o-phthaldialdehyde | Analytical Chemistry | 1979 | 1,583 |
| 45 | Quantitative Determination of Monosaccharides as Their Alditol Acetates by Gas Liquid Chromatography. | Analytical Chemistry | 1965 | 1,574 |
| 46 | A Bacterial Method for the Nitrogen Isotopic Analysis of Nitrate in Seawater and Freshwater | Analytical Chemistry | 2001 | 1,560 |
| 47 | Guidelines for data acquisition and data quality evaluation in environmental chemistry | Analytical Chemistry | 1980 | 1,456 |
| 48 | Analytical Properties of the Nanoelectrospray Ion Source | Analytical Chemistry | 1996 | 1,448 |
| 49 | Infrared Spectra and Characteristic Frequencies of Inorganic Ions | Analytical Chemistry | 1952 | 1,432 |
| 50 | Electrochemical Sensing and Biosensing Platform Based on Chemically Reduced Graphene Oxide | Analytical Chemistry | 2009 | 1,432 |