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| 2 | Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review | Gastroenterology | 2012 | 3,446 |
| 3 | Functional Bowel Disorders | Gastroenterology | 2006 | 3,383 |
| 4 | Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium | Gastroenterology | 2011 | 2,710 |
| 5 | Biology of Incretins: GLP-1 and GIP | Gastroenterology | 2007 | 2,662 |
| 6 | Development of a Crohn's Disease Activity Index | Gastroenterology | 1976 | 2,624 |
| 7 | Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity☆, ☆☆ | Gastroenterology | 1999 | 2,407 |
| 8 | Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma | Gastroenterology | 2012 | 2,275 |
| 9 | MAFLD: A Consensus-Driven Proposed Nomenclature for Metabolic Associated Fatty Liver Disease | Gastroenterology | 2020 | 2,262 |
| 10 | Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis | Gastroenterology | 2017 | 2,191 |
| 11 | Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease | Gastroenterology | 2015 | 2,136 |
| 12 | Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis | Gastroenterology | 2013 | 2,107 |
| 13 | The Natural History of Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study | Gastroenterology | 2005 | 2,069 |
| 14 | Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences | Gastroenterology | 2004 | 2,039 |
| 15 | MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer | Gastroenterology | 2007 | 2,028 |
| 16 | Bowel Disorders | Gastroenterology | 2016 | 2,019 |
| 17 | Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome | Gastroenterology | 2012 | 2,011 |
| 18 | Mechanisms of Hepatic Fibrogenesis | Gastroenterology | 2008 | 1,981 |
| 19 | STRIDE-II: An Update on the Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE) Initiative of the International Organization for the Study of IBD (IOIBD): Determining Therapeutic Goals for Treat-to-Target strategies in IBD | Gastroenterology | 2021 | 1,912 |
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| 21 | Model for end-stage liver disease (MELD) and allocation of donor livers | Gastroenterology | 2003 | 1,817 |
| 22 | Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas | Gastroenterology | 1994 | 1,812 |
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| 24 | Prospective comparison of transient elastography, Fibrotest, APRI, and liver biopsy for the assessment of fibrosis in chronic hepatitis C | Gastroenterology | 2005 | 1,745 |
| 25 | Evidence for Gastrointestinal Infection of SARS-CoV-2 | Gastroenterology | 2020 | 1,723 |
| 26 | Weight Loss Through Lifestyle Modification Significantly Reduces Features of Nonalcoholic Steatohepatitis | Gastroenterology | 2015 | 1,674 |
| 27 | Adalimumab for Maintenance of Clinical Response and Remission in Patients With Crohn’s Disease: The CHARM Trial | Gastroenterology | 2007 | 1,669 |
| 28 | Microsatellite Instability in Colorectal Cancer | Gastroenterology | 2010 | 1,596 |
| 29 | Prevalence of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis Among a Largely Middle-Aged Population Utilizing Ultrasound and Liver Biopsy: A Prospective Study | Gastroenterology | 2011 | 1,524 |
| 30 | Colorectal cancer screening and surveillance: Clinical guidelines and rationale?Update based on new evidence | Gastroenterology | 2003 | 1,523 |
| 31 | Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology | Gastroenterology | 2008 | 1,500 |
| 32 | Functional Gastrointestinal Disorders: History, Pathophysiology, Clinical Features, and Rome IV | Gastroenterology | 2016 | 1,499 |
| 33 | Epidemiology and Natural History of Inflammatory Bowel Diseases | Gastroenterology | 2011 | 1,498 |
| 34 | Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities | Gastroenterology | 2001 | 1,495 |
| 35 | Sampling Variability of Liver Biopsy in Nonalcoholic Fatty Liver Disease | Gastroenterology | 2005 | 1,495 |
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| 37 | Prevalence and clinical spectrum of gastroesophageal reflux: A population-based study in Olmsted County, Minnesota | Gastroenterology | 1997 | 1,473 |
| 38 | Gluten, major histocompatibility complex, and the small intestine | Gastroenterology | 1992 | 1,468 |
| 39 | The Functional Gastrointestinal Disorders and the Rome III Process | Gastroenterology | 2006 | 1,464 |
| 40 | Inflammation and Colon Cancer | Gastroenterology | 2010 | 1,464 |
| 41 | The utility of radiological imaging in nonalcoholic fatty liver disease | Gastroenterology | 2002 | 1,444 |
| 42 | Early indicators of prognosis in fulminant hepatic failure | Gastroenterology | 1989 | 1,438 |
| 43 | Guidelines for Colonoscopy Surveillance After Screening and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer | Gastroenterology | 2012 | 1,434 |
| 44 | Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study | Gastroenterology | 2021 | 1,415 |
| 45 | Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets | Gastroenterology | 2011 | 1,407 |
| 46 | Burden of Gastrointestinal Disease in the United States: 2012 Update | Gastroenterology | 2012 | 1,379 |
| 47 | Microbial Influences in Inflammatory Bowel Diseases | Gastroenterology | 2008 | 1,331 |
| 48 | The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead | Gastroenterology | 2014 | 1,311 |
| 49 | The Epidemiology of Pancreatitis and Pancreatic Cancer | Gastroenterology | 2013 | 1,308 |
| 50 | Functional Gastroduodenal Disorders | Gastroenterology | 2006 | 1,306 |