5.6(top 2%)
Impact Factor
6(top 2%)
extended IF
79(top 5%)
H-Index
3K
authors
2.8K
papers
49.3K
citations
2.9K
citing journals
29K
citing authors

Most Cited Articles of Journal of Enzyme Inhibition and Medicinal Chemistry

TitleYearCitations
Carbonic anhydrases: current state of the art, therapeutic applications and future prospects2004532
How many carbonic anhydrase inhibition mechanisms exist?2016485
Structure-based drug discovery of carbonic anhydrase inhibitors2012483
Matrix metalloproteinases (MMPs), the main extracellular matrix (ECM) enzymes in collagen degradation, as a target for anticancer drugs2016454
The role of fluorine in medicinal chemistry2007364
Inhibition of SARS-CoV 3CL protease by flavonoids2020344
Skin whitening agents: medicinal chemistry perspective of tyrosinase inhibitors2017337
A comprehensive review on tyrosinase inhibitors2019331
Pharmacological significance of triazole scaffold2011301
An overview of the alpha-, beta- and gamma-carbonic anhydrases from Bacteria: can bacterial carbonic anhydrases shed new light on evolution of bacteria?2015279
Biological evaluation of several coumarin derivatives designed as possible anti-inflammatory/antioxidant agents2003245
Sulfa and trimethoprim-like drugs - antimetabolites acting as carbonic anhydrase, dihydropteroate synthase and dihydrofolate reductase inhibitors2014212
Beta-lactamase database (BLDB) - structure and function2017187
Isatin-derived antibacterial and antifungal compounds and their transition metal complexes2004173
Structural annotation of human carbonic anhydrases2013162
α-Glucosidase inhibition by flavonoids: an in vitro and in silico structure-activity relationship study2017153
Taking advantage of tumor cell adaptations to hypoxia for developing new tumor markers and treatment strategies2009153
Synthesis of 4-benzyl-1,3-thiazole derivatives as potential anti-inflammatory agents: an analogue-based drug design approach2009153
Evaluation of polyphenols from Broussonetia papyrifera as coronavirus protease inhibitors2017151
Natural, semisynthetic and synthetic tyrosinase inhibitors2016144
A new approach to antiglaucoma drugs: carbonic anhydrase inhibitors with or without NO donating moieties. Mechanism of action and preliminary pharmacology2012138
Metalloantibiotics: synthesis and antibacterial activity of cobalt(II), copper(II), nickel(II) and zinc(II) complexes of kefzol2004135
Rosmarinic acid inhibits some metabolic enzymes including glutathione S-transferase, lactoperoxidase, acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase isoenzymes2016134
In vitro antioxidant activity of silymarin2009132
Metal binding and antibacterial activity of ciprofloxacin complexes2005130