Aortic pulse wave velocity improves cardiovascular event prediction: an individual participant meta-analysis of prospective observational data from 17,635 subjects | Journal of the American College of Cardiology | 2014 | 1.1K |
Plasma membrane translocation of trimerized MLKL protein is required for TNF-induced necroptosis | Nature Cell Biology | 2014 | 790 |
Sixth INTERMACS annual report: a 10,000-patient database | Journal of Heart and Lung Transplantation | 2014 | 664 |
Neurogenesis in the striatum of the adult human brain | Cell | 2014 | 638 |
Computed tomography angiography and perfusion to assess coronary artery stenosis causing perfusion defects by single photon emission computed tomography: the CORE320 study | European Heart Journal | 2014 | 310 |
Dynamics of oligodendrocyte generation and myelination in the human brain | Cell | 2014 | 280 |
Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks | American Journal of Human Genetics | 2014 | 233 |
Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia | Cancer Research | 2014 | 170 |
Pharmacogenetic meta-analysis of genome-wide association studies of LDL cholesterol response to statins | Nature Communications | 2014 | 160 |
Caval-aortic access to allow transcatheter aortic valve replacement in otherwise ineligible patients: initial human experience | Journal of the American College of Cardiology | 2014 | 137 |
STARTS-2: long-term survival with oral sildenafil monotherapy in treatment-naive pediatric pulmonary arterial hypertension | Circulation | 2014 | 129 |
Recurrent epimutation of SDHC in gastrointestinal stromal tumors | Science Translational Medicine | 2014 | 129 |
Melanosome transfer: it is best to give and receive | Current Opinion in Cell Biology | 2014 | 112 |
B-type natriuretic peptide and C-reactive protein in the prediction of atrial fibrillation risk: the CHARGE-AF Consortium of community-based cohort studies | Europace | 2014 | 112 |
TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4(+) T cell fate and interact with Runx3 to silence Cd4 in CD8(+) T cells | Nature Immunology | 2014 | 105 |
Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases | Molecular Systems Biology | 2014 | 101 |
A genome-wide association study identifies 6p21 as novel risk locus for dilated cardiomyopathy | European Heart Journal | 2014 | 97 |
Multiscale Free Energy Simulations: An Efficient Method for Connecting Classical MD Simulations to QM or QM/MM Free Energies Using Non-Boltzmann Bennett Reweighting Schemes | Journal of Chemical Theory and Computation | 2014 | 96 |
Forelimb treatment in a large cohort of dystrophic dogs supports delivery of a recombinant AAV for exon skipping in Duchenne patients | Molecular Therapy | 2014 | 95 |
Influenza a virus assembly intermediates fuse in the cytoplasm | PLoS Pathogens | 2014 | 94 |
GCN5-like protein 1 (GCN5L1) controls mitochondrial content through coordinated regulation of mitochondrial biogenesis and mitophagy | Journal of Biological Chemistry | 2014 | 91 |
An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge | Genome Biology | 2014 | 86 |
Genetically engineered pigs and target-specific immunomodulation provide significant graft survival and hope for clinical cardiac xenotransplantation | Journal of Thoracic and Cardiovascular Surgery | 2014 | 84 |
One-year heterotopic cardiac xenograft survival in a pig to baboon model | American Journal of Transplantation | 2014 | 84 |
Risk factors for death in 632 patients with sickle cell disease in the United States and United Kingdom | PLoS ONE | 2014 | 82 |