A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial | Lancet, The | 2015 | 1.5K |
A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease | Nature Genetics | 2015 | 1.3K |
Neoadjuvant chemoradiotherapy plus surgery versus surgery alone for oesophageal or junctional cancer (CROSS): long-term results of a randomised controlled trial | Lancet Oncology, The | 2015 | 1.3K |
Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study | Intensive Care Medicine | 2015 | 1.1K |
Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota | Nature | 2015 | 1.1K |
Mortality risk attributable to high and low ambient temperature: a multicountry observational study | Lancet, The | 2015 | 1.1K |
Cumulative meta-analysis of interleukins 6 and 1β, tumour necrosis factor α and C-reactive protein in patients with major depressive disorder | Brain, Behavior, and Immunity | 2015 | 581 |
Disability weights for the Global Burden of Disease 2013 study | The Lancet Global Health | 2015 | 527 |
The number of subjects per variable required in linear regression analyses | Journal of Clinical Epidemiology | 2015 | 515 |
Magnetic resonance imaging-targeted biopsy may enhance the diagnostic accuracy of significant prostate cancer detection compared to standard transrectal ultrasound-guided biopsy: a systematic review and meta-analysis | European Urology | 2015 | 454 |
The psychological burden of skin diseases: a cross-sectional multicenter study among dermatological out-patients in 13 European countries | Journal of Investigative Dermatology | 2015 | 394 |
Epidemiology of traumatic brain injury in Europe | Acta Neurochirurgica | 2015 | 382 |
Estimated glomerular filtration rate and albuminuria for prediction of cardiovascular outcomes: a collaborative meta-analysis of individual participant data | Lancet Diabetes and Endocrinology,the | 2015 | 381 |
Antibiotic Therapy vs Appendectomy for Treatment of Uncomplicated Acute Appendicitis: The APPAC Randomized Clinical Trial | JAMA - Journal of the American Medical Association | 2015 | 376 |
Long working hours and risk of coronary heart disease and stroke: a systematic review and meta-analysis of published and unpublished data for 603,838 individuals | Lancet, The | 2015 | 368 |
The rising tide of polypharmacy and drug-drug interactions: population database analysis 1995-2010 | BMC Medicine | 2015 | 366 |
International photographic classification and grading system for myopic maculopathy | American Journal of Ophthalmology | 2015 | 351 |
Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis | Nature Genetics | 2015 | 329 |
Recent trends in incidence of five common cancers in 26 European countries since 1988: Analysis of the European Cancer Observatory | European Journal of Cancer | 2015 | 319 |
Sample Size Requirements for Discrete-Choice Experiments in Healthcare: a Practical Guide | Patient | 2015 | 297 |
The expanding role of primary care in cancer control | Lancet Oncology, The | 2015 | 297 |
Even a low-dose of moderate-to-vigorous physical activity reduces mortality by 22% in adults aged ≥60 years: a systematic review and meta-analysis | British Journal of Sports Medicine | 2015 | 294 |
Global cancer surgery: delivering safe, affordable, and timely cancer surgery | Lancet Oncology, The | 2015 | 290 |
Elevated fetal steroidogenic activity in autism | Molecular Psychiatry | 2015 | 286 |
The influence of childhood traffic-related air pollution exposure on asthma, allergy and sensitization: a systematic review and a meta-analysis of birth cohort studies | Allergy: European Journal of Allergy and Clinical Immunology | 2015 | 279 |