Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls | Nature | 2007 | 7.8K |
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity | Science | 2007 | 3.3K |
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility gene | Nature Genetics | 2007 | 719 |
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A | Nature | 2007 | 421 |
A systematic genetic assessment of 1,433 sequence variants of unknown clinical significance in the BRCA1 and BRCA2 breast cancer-predisposition genes | American Journal of Human Genetics | 2007 | 360 |
Common variants in WFS1 confer risk of type 2 diabetes | Nature Genetics | 2007 | 296 |
Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival | Breast Cancer Research | 2007 | 230 |
RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies | American Journal of Human Genetics | 2007 | 204 |
Cancer genetics of epigenetic genes | Human Molecular Genetics | 2007 | 200 |
TCF7L2 polymorphisms modulate proinsulin levels and beta-cell function in a British Europid population | Diabetes | 2007 | 137 |
Genetic variation at the CYP19A1 locus predicts circulating estrogen levels but not breast cancer risk in postmenopausal women | Cancer Research | 2007 | 134 |
Association between common variation in 120 candidate genes and breast cancer risk | PLoS Genetics | 2007 | 118 |
The V103I polymorphism of the MC4R gene and obesity: population based studies and meta-analysis of 29 563 individuals | International Journal of Obesity | 2007 | 111 |
Healthy lifestyle choices: could sense of coherence aid health promotion? | Journal of Epidemiology and Community Health | 2007 | 104 |
Psychological impact of screening for type 2 diabetes: controlled trial and comparative study embedded in the ADDITION (Cambridge) randomised controlled trial | BMJ, The | 2007 | 100 |
Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk | Breast Cancer Research | 2007 | 79 |
Tagging single nucleotide polymorphisms in cell cycle control genes and susceptibility to invasive epithelial ovarian cancer | Cancer Research | 2007 | 75 |
Psychosocial factors and incident asthma hospital admissions in the EPIC-Norfolk cohort study | Allergy: European Journal of Allergy and Clinical Immunology | 2007 | 73 |
EPIC-Heart: the cardiovascular component of a prospective study of nutritional, lifestyle and biological factors in 520,000 middle-aged participants from 10 European countries | European Journal of Epidemiology | 2007 | 69 |
Contribution of BRCA1 and BRCA2 mutations to inherited ovarian cancer | Human Mutation | 2007 | 67 |
No association between the BDNF Val66Met polymorphism and mood status in a non-clinical community sample of 7389 older adults | Journal of Psychiatric Research | 2007 | 66 |
Association between the T-381C polymorphism of the brain natriuretic peptide gene and risk of type 2 diabetes in human populations | Human Molecular Genetics | 2007 | 64 |
More acidic dietary acid-base load is associated with reduced calcaneal broadband ultrasound attenuation in women but not in men: results from the EPIC-Norfolk cohort study | American Journal of Clinical Nutrition | 2007 | 64 |
Does the fetal genotype affect maternal physiology during pregnancy? | Trends in Molecular Medicine | 2007 | 63 |
Multi-factor dimensionality reduction applied to a large prospective investigation on gene-gene and gene-environment interactions | Carcinogenesis | 2007 | 62 |