Treatable traits: toward precision medicine of chronic airway diseases | European Respiratory Journal | 2016 | 487 |
Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function | Nature Communications | 2016 | 295 |
Low-Dose versus Standard-Dose Intravenous Alteplase in Acute Ischemic Stroke | New England Journal of Medicine | 2016 | 259 |
WSES Jerusalem guidelines for diagnosis and treatment of acute appendicitis | World Journal of Emergency Surgery | 2016 | 198 |
Continuous versus Intermittent β-Lactam Infusion in Severe Sepsis. A Meta-analysis of Individual Patient Data from Randomized Trials | American Journal of Respiratory and Critical Care Medicine | 2016 | 192 |
2016 WSES guidelines on acute calculous cholecystitis | World Journal of Emergency Surgery | 2016 | 176 |
Defining secondary progressive multiple sclerosis | Brain | 2016 | 172 |
Disorders of sex development: insights from targeted gene sequencing of a large international patient cohort | Genome Biology | 2016 | 166 |
Conservative versus Liberal Oxygenation Targets for Mechanically Ventilated Patients. A Pilot Multicenter Randomized Controlled Trial | American Journal of Respiratory and Critical Care Medicine | 2016 | 150 |
Treatment of Unexplained Chronic Cough: CHEST Guideline and Expert Panel Report | Chest | 2016 | 140 |
Evidence of effectiveness of a fracture liaison service to reduce the re-fracture rate | Osteoporosis International | 2016 | 123 |
Combination of Vancomycin and β-Lactam Therapy for Methicillin-Resistant Staphylococcus aureus Bacteremia: A Pilot Multicenter Randomized Controlled Trial | Clinical Infectious Diseases | 2016 | 117 |
Predictors of long-term disability accrual in relapse-onset multiple sclerosis | Annals of Neurology | 2016 | 117 |
Pregabalin and Speech Pathology Combination Therapy for Refractory Chronic Cough: A Randomized Controlled Trial | Chest | 2016 | 117 |
WSES Guidelines for the management of acute left sided colonic diverticulitis in the emergency setting | World Journal of Emergency Surgery | 2016 | 115 |
Neutrophil extracellular traps are associated with inflammation in chronic airway disease | Respirology | 2016 | 112 |
Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD | International Journal of COPD | 2016 | 98 |
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) | World Journal of Emergency Surgery | 2016 | 95 |
Protracted bacterial bronchitis: The last decade and the road ahead | Pediatric Pulmonology | 2016 | 86 |
No evidence that protein truncating variants in BRIP1 are associated with breast cancer risk: implications for gene panel testing | Journal of Medical Genetics | 2016 | 83 |
A benchmarking tool to evaluate computer tomography perfusion infarct core predictions against a DWI standard | Journal of Cerebral Blood Flow and Metabolism | 2016 | 81 |
Whole-Brain CT Perfusion to Quantify Acute Ischemic Penumbra and Core | Radiology | 2016 | 78 |
Phenotypic insights into ADCY5-associated disease | Movement Disorders | 2016 | 78 |
Acute Stroke Imaging Research Roadmap III Imaging Selection and Outcomes in Acute Stroke Reperfusion Clinical Trials: Consensus Recommendations and Further Research Priorities | Stroke | 2016 | 77 |
Length of stay and mortality associated with healthcare-associated urinary tract infections: a multi-state model | Journal of Hospital Infection | 2016 | 74 |