| Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19 | New England Journal of Medicine | 2021 | 227 |
| Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19 | New England Journal of Medicine | 2021 | 203 |
| Suicide trends in the early months of the COVID-19 pandemic: an interrupted time-series analysis of preliminary data from 21 countries | Lancet Psychiatry,the | 2021 | 167 |
| Sensitivity of Nasopharyngeal Swabs and Saliva for the Detection of Severe Acute Respiratory Syndrome Coronavirus 2 | Clinical Infectious Diseases | 2021 | 119 |
| Surviving Sepsis Campaign Guidelines on the Management of Adults With Coronavirus Disease 2019 (COVID-19) in the ICU: First Update | Critical Care Medicine | 2021 | 119 |
| Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet Respiratory Medicine,the | 2021 | 112 |
| Peginterferon lambda for the treatment of outpatients with COVID-19: a phase 2, placebo-controlled randomised trial | Lancet Respiratory Medicine,the | 2021 | 89 |
| Technology of deep brain stimulation: current status and future directions | Nature Reviews Neurology | 2021 | 87 |
| A77 A REUSABLE POLYCARBONATE BOX TO DECREASE DROPLET CONTAMINATION DURING UPPER ENDOSCOPY: A SIMULATION-BASED STUDY FOR THE COVID-19 PANDEMIC | Journal of the Canadian Association of Gastroenterology | 2021 | 78 |
| Use of Expressed Breastmilk at Two Weeks Postpartum Is Associated With Early Cessation and Non-exclusive Breastmilk Feeding for Six Months in a Cohort of Vulnerable Women | Current Developments in Nutrition | 2021 | 78 |
| THER-01. Targeted therapy and intracranial metastatic disease: a population-based retrospective cohort study | Neuro-Oncology Advances | 2021 | 78 |
| Single- and Multi-Fraction Stereotactic Radiosurgery Dose Tolerances of the Optic Pathways | International Journal of Radiation Oncology Biology Physics | 2021 | 53 |
| Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial | Nature Medicine | 2021 | 53 |
| A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease | Nature Medicine | 2021 | 51 |
| Anti-PEG IgE in anaphylaxis associated with polyethylene glycol | Journal of Allergy and Clinical Immunology: in Practice | 2021 | 51 |
| Applications of focused ultrasound in the brain: from thermoablation to drug delivery | Nature Reviews Neurology | 2021 | 49 |
| CCS/CHFS Heart Failure Guidelines Update: Defining a New Pharmacologic Standard of Care for Heart Failure With Reduced Ejection Fraction | Canadian Journal of Cardiology | 2021 | 48 |
| COVID-FACT: A Fully-Automated Capsule Network-Based Framework for Identification of COVID-19 Cases from Chest CT Scans | Frontiers in Artificial Intelligence | 2021 | 41 |
| Single- and Multifraction Stereotactic Radiosurgery Dose/Volume Tolerances of the Brain | International Journal of Radiation Oncology Biology Physics | 2021 | 40 |
| COVID-CT-MD, COVID-19 computed tomography scan dataset applicable in machine learning and deep learning | Scientific Data | 2021 | 38 |
| S-Gene Target Failure as a Marker of Variant B.1.1.7 Among SARS-CoV-2 Isolates in the Greater Toronto Area, December 2020 to March 2021 | JAMA - Journal of the American Medical Association | 2021 | 38 |
| Global impact of COVID-19 on stroke care | International Journal of Stroke | 2021 | 36 |
| Pemetrexed plus platinum with or without pembrolizumab in patients with previously untreated metastatic nonsquamous NSCLC: protocol-specified final analysis from KEYNOTE-189 | Annals of Oncology | 2021 | 35 |
| Assessment of Sentinel Lymph Node Biopsy vs Lymphadenectomy for Intermediate- and High-Grade Endometrial Cancer Staging | JAMA Surgery | 2021 | 35 |
| Definitions and Clinical Trial Design Principles for Coronary Artery Chronic Total Occlusion Therapies: CTO-ARC Consensus Recommendations | Circulation | 2021 | 34 |
