| Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins | Cell | 2000 | 2K |
| Impact of diabetes on long-term prognosis in patients with unstable angina and non-Q-wave myocardial infarction: results of the OASIS (Organization to Assess Strategies for Ischemic Syndromes) Registry | Circulation | 2000 | 598 |
| Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 587 |
| Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype | Current Biology | 2000 | 452 |
| Factors influencing outcome following mild traumatic brain injury in adults | Journal of the International Neuropsychological Society | 2000 | 436 |
| Gigantism in mice lacking suppressor of cytokine signalling-2 | Nature | 2000 | 404 |
| Initiation of apoptosis by granzyme B requires direct cleavage of bid, but not direct granzyme B-mediated caspase activation | Journal of Experimental Medicine | 2000 | 300 |
| The Drosophila caspase DRONC is regulated by DIAP1 | EMBO Journal | 2000 | 278 |
| Selfotel in acute ischemic stroke : possible neurotoxic effects of an NMDA antagonist | Stroke | 2000 | 274 |
| VEGF-C and VEGF-D expression in neuroendocrine cells and their receptor, VEGFR-3, in fenestrated blood vessels in human tissues | FASEB Journal | 2000 | 272 |
| Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes | Diabetes | 2000 | 271 |
| Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species | Molecular Microbiology | 2000 | 247 |
| Aldose reductase and the role of the polyol pathway in diabetic nephropathy | Kidney International | 2000 | 216 |
| Effect of the androgen receptor CAG repeat polymorphism on transcriptional activity: specificity in prostate and non-prostate cell lines | Journal of Molecular Endocrinology | 2000 | 214 |
| Proteomic analysis of the human colon carcinoma cell line (LIM 1215): development of a membrane protein database | Electrophoresis | 2000 | 209 |
| The proapoptotic BH3-only protein bim is expressed in hematopoietic, epithelial, neuronal, and germ cells | American Journal of Pathology | 2000 | 201 |
| The angiosomes of the head and neck: anatomic study and clinical applications | Plastic and Reconstructive Surgery | 2000 | 196 |
| The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression | EMBO Journal | 2000 | 192 |
| Collagen-induced arthritis in C57BL/6 (H-2b) mice: new insights into an important disease model of rheumatoid arthritis | European Journal of Immunology | 2000 | 184 |
| Extracellular matrix and the brain: components and function | Journal of Clinical Neuroscience | 2000 | 183 |
| bcl-2 transgene expression inhibits apoptosis in the germinal center and reveals differences in the selection of memory B cells and bone marrow antibody-forming cells | Journal of Experimental Medicine | 2000 | 179 |
| Rel induces interferon regulatory factor 4 (IRF-4) expression in lymphocytes: modulation of interferon-regulated gene expression by rel/nuclear factor kappaB | Journal of Experimental Medicine | 2000 | 168 |
| Renal xenografts from triple-transgenic pigs are not hyperacutely rejected but cause coagulopathy in non-immunosuppressed baboons | Transplantation | 2000 | 163 |
| Diagnosis of Wilson's disease: an experience over three decades | Gut | 2000 | 152 |
| Identification and analysis of error types in high-throughput genotyping | American Journal of Human Genetics | 2000 | 150 |
