| Vascular risk factors and diabetic neuropathy | New England Journal of Medicine | 2005 | 890 |
| SAPS 3--From evaluation of the patient to evaluation of the intensive care unit. Part 2: Development of a prognostic model for hospital mortality at ICU admission | Intensive Care Medicine | 2005 | 829 |
| Disrupting tumour blood vessels | Nature Reviews Cancer | 2005 | 793 |
| SAPS 3--From evaluation of the patient to evaluation of the intensive care unit. Part 1: Objectives, methods and cohort description | Intensive Care Medicine | 2005 | 493 |
| Guidelines for the diagnosis, investigation and management of polycythaemia/erythrocytosis | British Journal of Haematology | 2005 | 264 |
| A comparison of the efficacy and tolerability of solifenacin succinate and extended release tolterodine at treating overactive bladder syndrome: results of the STAR trial | European Urology | 2005 | 257 |
| Promoter hypermethylation is associated with tumor location, stage, and subsequent progression in transitional cell carcinoma | Journal of Clinical Oncology | 2005 | 249 |
| Anxiety in patients with epilepsy: systematic review and suggestions for clinical management | Epilepsy and Behavior | 2005 | 246 |
| Pet ownership and human health: a brief review of evidence and issues | BMJ, The | 2005 | 239 |
| Indigo carmine-assisted high-magnification chromoscopic colonoscopy for the detection and characterisation of intraepithelial neoplasia in ulcerative colitis: a prospective evaluation | Endoscopy | 2005 | 234 |
| Changes in liver volume from birth to adulthood: a meta-analysis | Liver Transplantation | 2005 | 231 |
| Agrammatic but numerate | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 228 |
| Sural nerve pathology in diabetic patients with minimal but progressive neuropathy | Diabetologia | 2005 | 221 |
| Androgens, insulin resistance and vascular disease in men | Clinical Endocrinology | 2005 | 219 |
| Management of the patient and family with neurofibromatosis 2: a consensus conference statement | British Journal of Neurosurgery | 2005 | 187 |
| The effects of antimuscarinic treatments in overactive bladder: a systematic review and meta-analysis | European Urology | 2005 | 182 |
| The role of urinary urgency and its measurement in the overactive bladder symptom syndrome: current concepts and future prospects | BJU International | 2005 | 176 |
| Decreased duration of mechanical ventilation when comparing analgesia-based sedation using remifentanil with standard hypnotic-based sedation for up to 10 days in intensive care unit patients: a randomised trial [ISRCTN47583497] | Critical Care | 2005 | 158 |
| Emphysematous changes and normal variation in smokers and COPD patients using diffusion 3He MRI | European Journal of Radiology | 2005 | 151 |
| Risk of a first venous thrombotic event in carriers of a familial thrombophilic defect. The European Prospective Cohort on Thrombophilia (EPCOT) | Journal of Thrombosis and Haemostasis | 2005 | 147 |
| The benefits of combined anti-platelet treatment in carotid artery stenting | European Journal of Vascular and Endovascular Surgery | 2005 | 141 |
| Combined helium-3/proton magnetic resonance imaging measurement of ventilated lung volumes in smokers compared to never-smokers | Journal of Magnetic Resonance Imaging | 2005 | 140 |
| Sequence- and schedule-dependent enhancement of zoledronic acid induced apoptosis by doxorubicin in breast and prostate cancer cells | International Journal of Cancer | 2005 | 138 |
| Risk factors for cardiac autonomic neuropathy in type 1 diabetes mellitus | Diabetologia | 2005 | 138 |
| The expression and roles of Toll-like receptors in the biology of the human neutrophil | Journal of Leukocyte Biology | 2005 | 125 |
