Direct reprogramming of human fibroblasts to functional and expandable hepatocytes | Cell Stem Cell | 2014 | 351 |
Targeting interleukin-6 in inflammatory autoimmune diseases and cancers | Pharmacology & Therapeutics | 2014 | 333 |
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis | Proceedings of the National Academy of Sciences of the United States of America | 2014 | 307 |
Effect of probiotics on inducing remission and maintaining therapy in ulcerative colitis, Crohn's disease, and pouchitis: meta-analysis of randomized controlled trials | Inflammatory Bowel Diseases | 2014 | 260 |
IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L | Immunity | 2014 | 238 |
Overexpression of long non-coding RNA HOTAIR predicts poor patient prognosis and promotes tumor metastasis in epithelial ovarian cancer | Gynecologic Oncology | 2014 | 183 |
Development of T cells redirected to glypican-3 for the treatment of hepatocellular carcinoma | Clinical Cancer Research | 2014 | 177 |
Hepatic RIG-I predicts survival and interferon-α therapeutic response in hepatocellular carcinoma | Cancer Cell | 2014 | 147 |
Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index | Human Molecular Genetics | 2014 | 141 |
Prostate stem cell antigen antibody-conjugated multiwalled carbon nanotubes for targeted ultrasound imaging and drug delivery | Biomaterials | 2014 | 140 |
Association between Faecalibacterium prausnitzii Reduction and Inflammatory Bowel Disease: A Meta-Analysis and Systematic Review of the Literature | Gastroenterology Research and Practice | 2014 | 139 |
Tumor penetrability and anti-angiogenesis using iRGD-mediated delivery of doxorubicin-polymer conjugates | Biomaterials | 2014 | 137 |
Insights into echo-attenuated plaques, echolucent plaques, and plaques with spotty calcification: novel findings from comparisons among intravascular ultrasound, near-infrared spectroscopy, and pathological histology in 2,294 human coronary artery segments | Journal of the American College of Cardiology | 2014 | 136 |
FGFR2 amplification has prognostic significance in gastric cancer: results from a large international multicentre study | British Journal of Cancer | 2014 | 129 |
Alterations in the microbiota drive interleukin-17C production from intestinal epithelial cells to promote tumorigenesis | Immunity | 2014 | 120 |
FTO genetic variants, dietary intake and body mass index: insights from 177,330 individuals | Human Molecular Genetics | 2014 | 120 |
TRIM59 is up-regulated in gastric tumors, promoting ubiquitination and degradation of p53 | Gastroenterology | 2014 | 103 |
Contributions of epithelial-mesenchymal transition and cancer stem cells to the development of castration resistance of prostate cancer | Molecular Cancer | 2014 | 101 |
ATF6 mediates a pro-inflammatory synergy between ER stress and TLR activation in the pathogenesis of liver ischemia-reperfusion injury | American Journal of Transplantation | 2014 | 100 |
Endoscopic versus microscopic transsphenoidal pituitary adenoma surgery: a meta-analysis | World Journal of Surgical Oncology | 2014 | 96 |
Roles of microRNAs during prostatic tumorigenesis and tumor progression | Oncogene | 2014 | 96 |
Prostate cancer in Asia: A collaborative report | Asian Journal of Urology | 2014 | 95 |
miRNA-200c inhibits invasion and metastasis of human non-small cell lung cancer by directly targeting ubiquitin specific peptidase 25 | Molecular Cancer | 2014 | 94 |
Activating mutations in PTPN3 promote cholangiocarcinoma cell proliferation and migration and are associated with tumor recurrence in patients | Gastroenterology | 2014 | 92 |
Minimally invasive transforaminal lumbar interbody fusion (MI-TLIF): surgical technique, long-term 4-year prospective outcomes, and complications compared with an open TLIF cohort | Neurosurgery Clinics of North America | 2014 | 90 |