Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk | Nature | 2011 | 1.6K |
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 | Nature Genetics | 2011 | 1K |
The Lung Image Database Consortium (LIDC) and Image Database Resource Initiative (IDRI): a completed reference database of lung nodules on CT scans | Medical Physics | 2011 | 999 |
Guidelines for the management of inflammatory bowel disease in adults | Gut | 2011 | 927 |
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility | Nature Genetics | 2011 | 646 |
Tracking of obesity-related behaviours from childhood to adulthood: A systematic review | Maturitas | 2011 | 576 |
SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner | Molecular and Cellular Biology | 2011 | 493 |
Matrix stiffness modulates proliferation, chemotherapeutic response, and dormancy in hepatocellular carcinoma cells | Hepatology | 2011 | 400 |
Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology | PLoS Genetics | 2011 | 383 |
Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms | Blood | 2011 | 365 |
Susceptibility to amoxicillin-clavulanate-induced liver injury is influenced by multiple HLA class I and II alleles | Gastroenterology | 2011 | 359 |
Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 340 |
Expected value and prediction error abnormalities in depression and schizophrenia | Brain | 2011 | 315 |
A systematic review of hepatitis C virus epidemiology in Europe, Canada and Israel | Liver International | 2011 | 293 |
Fermentation in the human large intestine: its physiologic consequences and the potential contribution of prebiotics | Journal of Clinical Gastroenterology | 2011 | 260 |
Effect of fibroblast growth factor NV1FGF on amputation and death: a randomised placebo-controlled trial of gene therapy in critical limb ischaemia | Lancet, The | 2011 | 255 |
Evidence for biological effects of metformin in operable breast cancer: a pre-operative, window-of-opportunity, randomized trial | Breast Cancer Research and Treatment | 2011 | 217 |
Living and dying with severe chronic obstructive pulmonary disease: multi-perspective longitudinal qualitative study | BMJ, The | 2011 | 205 |
Long-term follow-up of patients on home parenteral nutrition in Europe: implications for intestinal transplantation | Gut | 2011 | 197 |
Mental practice with motor imagery in stroke recovery: randomized controlled trial of efficacy | Brain | 2011 | 196 |
Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21 | Human Molecular Genetics | 2011 | 178 |
Improving recruitment of older people to research through good practice | Age and Ageing | 2011 | 170 |
Pannexins in ischemia-induced neurodegeneration | Proceedings of the National Academy of Sciences of the United States of America | 2011 | 166 |
Burden of antimicrobial resistance in European hospitals: excess mortality and length of hospital stay associated with bloodstream infections due to Escherichia coli resistant to third-generation cephalosporins | Journal of Antimicrobial Chemotherapy | 2011 | 163 |
Switching TGFβ from a tumor suppressor to a tumor promoter | Current Opinion in Genetics and Development | 2011 | 162 |