A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity | Science | 2007 | 3.3K |
A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants | Science | 2007 | 2.3K |
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes | Science | 2007 | 1.8K |
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases | Oncogene | 2007 | 623 |
Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes | Nature Genetics | 2007 | 616 |
Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema | Nature Genetics | 2007 | 510 |
Adding social deprivation and family history to cardiovascular risk assessment: the ASSIGN score from the Scottish Heart Health Extended Cohort (SHHEC) | Heart | 2007 | 394 |
Hardwiring the brain: endocannabinoids shape neuronal connectivity | Science | 2007 | 380 |
A common variant of HMGA2 is associated with adult and childhood height in the general population | Nature Genetics | 2007 | 330 |
Common variants in WFS1 confer risk of type 2 diabetes | Nature Genetics | 2007 | 296 |
Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A gene | PLoS Medicine | 2007 | 279 |
A potent cytotoxic photoactivated platinum complex | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 267 |
Carbohydrate terminology and classification | European Journal of Clinical Nutrition | 2007 | 247 |
Microbial biofilms in the human gastrointestinal tract | Journal of Applied Microbiology | 2007 | 247 |
Null mutations in the filaggrin gene (FLG) determine major susceptibility to early-onset atopic dermatitis that persists into adulthood | Journal of Investigative Dermatology | 2007 | 241 |
The deubiquitinating enzyme USP2a regulates the p53 pathway by targeting Mdm2 | EMBO Journal | 2007 | 221 |
Diastolic dysfunction in heart failure with preserved systolic function: need for objective evidence:results from the CHARM Echocardiographic Substudy-CHARMES | Journal of the American College of Cardiology | 2007 | 216 |
Identification of retinoic acid as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 216 |
Temporal and mechanistic dissociation of ATP and adenosine release during ischaemia in the mammalian hippocampus | Journal of Neurochemistry | 2007 | 191 |
Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis | Molecular Cell | 2007 | 188 |
How can drug discovery for psychiatric disorders be improved? | Nature Reviews Drug Discovery | 2007 | 186 |
Mucosa-associated bacterial diversity in relation to human terminal ileum and colonic biopsy samples | Applied and Environmental Microbiology | 2007 | 170 |
Neurosteroid modulation of synaptic and extrasynaptic GABA(A) receptors | | 2007 | 166 |
Adherence to insulin and its association with glycaemic control in patients with type 2 diabetes | QJM - Monthly Journal of the Association of Physicians | 2007 | 165 |
The Pedar in-shoe system: repeatability and normal pressure values | Gait and Posture | 2007 | 162 |