| 11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 782 |
| Value of natriuretic peptides in assessment of patients with possible new heart failure in primary care | Lancet, The | 1997 | 645 |
| Identification of genetic polymorphisms at the glutathione S-transferase Pi locus and association with susceptibility to bladder, testicular and prostate cancer | Carcinogenesis | 1997 | 507 |
| Adherence to insulin treatment, glycaemic control, and ketoacidosis in insulin-dependent diabetes mellitus. The DARTS/MEMO Collaboration. Diabetes Audit and Research in Tayside Scotland. Medicines Monitoring Unit | Lancet, The | 1997 | 394 |
| The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid | Proceedings of the National Academy of Sciences of the United States of America | 1997 | 334 |
| Association between beta 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics | Lancet, The | 1997 | 323 |
| Proposals for setting generally applicable quality goals solely based on biology | Annals of Clinical Biochemistry | 1997 | 285 |
| Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients | Cardiovascular Research | 1997 | 245 |
| Association of upper gastrointestinal toxicity of non-steroidal anti-inflammatory drugs with continued exposure: cohort study | BMJ: British Medical Journal | 1997 | 211 |
| Comparison of the prediction by 27 different factors of coronary heart disease and death in men and women of the Scottish Heart Health Study: cohort study | BMJ: British Medical Journal | 1997 | 207 |
| The diabetes audit and research in Tayside Scotland (DARTS) study: electronic record linkage to create a diabetes register. DARTS/MEMO Collaboration | BMJ: British Medical Journal | 1997 | 203 |
| Obesity as a disease | British Medical Bulletin | 1997 | 199 |
| Subunit-dependent interaction of the general anaesthetic etomidate with the gamma-aminobutyric acid type A receptor | British Journal of Pharmacology | 1997 | 184 |
| Non-steroidal anti-inflammatory drugs are associated with emergency admission to hospital for colitis due to inflammatory bowel disease | Gut | 1997 | 177 |
| Randomized trial comparing infrainguinal polytetrafluoroethylene bypass grafting with and without vein interposition cuff at the distal anastomosis. The Joint Vascular Research Group | Journal of Vascular Surgery | 1997 | 174 |
| The prohibitin family of mitochondrial proteins regulate replicative lifespan | Current Biology | 1997 | 173 |
| p53 is phosphorylated in vitro and in vivo by the delta and epsilon isoforms of casein kinase 1 and enhances the level of casein kinase 1 delta in response to topoisomerase-directed drugs | Oncogene | 1997 | 143 |
| U.K. Prospective Diabetes Study 27. Plasma lipids and lipoproteins at diagnosis of NIDDM by age and sex | Diabetes Care | 1997 | 133 |
| Systemic corticosteriod rapidly reverses bronchodilator subsensitivity induced by formoterol in asthmatic patients | American Journal of Respiratory and Critical Care Medicine | 1997 | 128 |
| Evidence that human class Theta glutathione S-transferase T1-1 can catalyse the activation of dichloromethane, a liver and lung carcinogen in the mouse. Comparison of the tissue distribution of GST T1-1 with that of classes Alpha, Mu and Pi GST in human | Biochemical Journal | 1997 | 128 |
| Metabolism of MPTP by cytochrome P4502D6 and the demonstration of 2D6 mRNA in human foetal and adult brain by in situ hybridization | Xenobiotica | 1997 | 116 |
| Measures for detecting systemic bioactivity with inhaled and intranasal corticosteroids | Thorax | 1997 | 106 |
| Regulation of human gamma-glutamylcysteine synthetase: co-ordinate induction of the catalytic and regulatory subunits in HepG2 cells | Biochemical Journal | 1997 | 106 |
| The interaction of general anaesthetics with recombinant GABAA and glycine receptors expressed in Xenopus laevis oocytes: a comparative study | British Journal of Pharmacology | 1997 | 106 |
| Oxidative DNA damage in CD34+ myelodysplastic cells is associated with intracellular redox changes and elevated plasma tumour necrosis factor-alpha concentration | British Journal of Haematology | 1997 | 104 |
