| Dopamine, learning and motivation | Nature Reviews Neuroscience | 2004 | 2.4K |
| Pathways towards and away from Alzheimer's disease | Nature | 2004 | 2.3K |
| Sociability and preference for social novelty in five inbred strains: an approach to assess autistic-like behavior in mice | Genes, Brain and Behavior | 2004 | 933 |
| Discovering endophenotypes for major depression | Neuropsychopharmacology | 2004 | 894 |
| Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore | Journal of Clinical Investigation | 2004 | 741 |
| BDNF and 5-HT: a dynamic duo in age-related neuronal plasticity and neurodegenerative disorders | Trends in Neurosciences | 2004 | 690 |
| Automated apparatus for quantitation of social approach behaviors in mice | Genes, Brain and Behavior | 2004 | 561 |
| The association between short sleep duration and obesity in young adults: a 13-year prospective study | Sleep | 2004 | 507 |
| The National Comorbidity Survey Replication (NCS-R): background and aims | International Journal of Methods in Psychiatric Research | 2004 | 485 |
| Designing mouse behavioral tasks relevant to autistic-like behaviors | Mental Retardation and Developmental Disabilities Research Reviews | 2004 | 366 |
| Metabolic syndrome amplifies the age-associated increases in vascular thickness and stiffness | Journal of the American College of Cardiology | 2004 | 349 |
| Physical activity, exercise, and inflammatory markers in older adults: findings from the Health, Aging and Body Composition Study | Journal of the American Geriatrics Society | 2004 | 336 |
| Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 333 |
| Regulation of the p300 HAT domain via a novel activation loop | Nature Structural and Molecular Biology | 2004 | 323 |
| Free testosterone and risk for Alzheimer disease in older men | Neurology | 2004 | 313 |
| Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain | Archives of General Psychiatry | 2004 | 298 |
| Cell cycle activation linked to neuronal cell death initiated by DNA damage | Neuron | 2004 | 292 |
| The association between physical function and lifestyle activity and exercise in the health, aging and body composition study | Journal of the American Geriatrics Society | 2004 | 284 |
| Caloric restriction increases neurotrophic factor levels and attenuates neurochemical and behavioral deficits in a primate model of Parkinson's disease | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 283 |
| Aging in rhesus monkeys: relevance to human health interventions | Science | 2004 | 272 |
| A single infusion of brain-derived neurotrophic factor into the ventral tegmental area induces long-lasting potentiation of cocaine seeking after withdrawal | Journal of Neuroscience | 2004 | 244 |
| Heart rate variability and its relation to prefrontal cognitive function: the effects of training and detraining | European Journal of Applied Physiology | 2004 | 242 |
| The anxiogenic drug yohimbine reinstates methamphetamine seeking in a rat model of drug relapse | Biological Psychiatry | 2004 | 238 |
| Sigma-1 receptor ligands: potential in the treatment of neuropsychiatric disorders | CNS Drugs | 2004 | 234 |
| Methamphetamine induces neuronal apoptosis via cross-talks between endoplasmic reticulum and mitochondria-dependent death cascades | FASEB Journal | 2004 | 233 |
