| Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial | Lancet, The | 2010 | 624 |
| Chronic gastrointestinal inflammation induces anxiety-like behavior and alters central nervous system biochemistry in mice | Gastroenterology | 2010 | 431 |
| Effects of CYP2C19 genotype on outcomes of clopidogrel treatment | New England Journal of Medicine | 2010 | 428 |
| Excess of rare variants in genes identified by genome-wide association study of hypertriglyceridemia | Nature Genetics | 2010 | 365 |
| Metabolic syndrome and risk of acute myocardial infarction a case-control study of 26,903 subjects from 52 countries | Journal of the American College of Cardiology | 2010 | 146 |
| A systematic review of the psychometric properties of the Constant-Murley score | Journal of Shoulder and Elbow Surgery | 2010 | 143 |
| Ethnic variation in adiponectin and leptin levels and their association with adiposity and insulin resistance | Diabetes Care | 2010 | 128 |
| The polypill in the prevention of cardiovascular diseases: key concepts, current status, challenges, and future directions | Circulation | 2010 | 120 |
| The 2010 Canadian Cardiovascular Society guidelines for the diagnosis and management of heart failure update: Heart failure in ethnic minority populations, heart failure and pregnancy, disease management, and quality improvement/assurance programs | Canadian Journal of Cardiology | 2010 | 105 |
| Risk of recurrent venous thromboembolism after stopping treatment in cohort studies: recommendation for acceptable rates and standardized reporting | Journal of Thrombosis and Haemostasis | 2010 | 77 |
| Lack of association between the Trp719Arg polymorphism in kinesin-like protein-6 and coronary artery disease in 19 case-control studies | Journal of the American College of Cardiology | 2010 | 75 |
| Effects of physical activity on cancer survival: a systematic review | Physiotherapy Canada Physiotherapie Canada | 2010 | 74 |
| "My child doesn't have a brain injury, he only has a concussion" | Pediatrics | 2010 | 71 |
| Assessing the volume-outcome hypothesis and region-level quality improvement interventions: pancreas cancer surgery in two Canadian Provinces | Annals of Surgical Oncology | 2010 | 63 |
| Management of complicated urinary tract infections in the era of antimicrobial resistance | Postgraduate Medicine | 2010 | 62 |
| Safety and feasibility of early hospital discharge in ST-segment elevation myocardial infarction--a prospective and randomized trial in low-risk primary percutaneous coronary intervention patients (the Safe-Depart Trial) | American Heart Journal | 2010 | 62 |
| Agents for the treatment of heparin-induced thrombocytopenia | Hematology/Oncology Clinics of North America | 2010 | 49 |
| Etiology of troponin elevation in critically ill patients | Journal of Critical Care | 2010 | 49 |
| Nurses' perceived barriers to optimal pain management in older adults on acute medical units | Applied Nursing Research | 2010 | 46 |
| The effect of abdominal support on functional outcomes in patients following major abdominal surgery: a randomized controlled trial | Physiotherapy Canada Physiotherapie Canada | 2010 | 42 |
| The use of well-characterized sera for the assessment of new diagnostic enzyme-immunoassays for the diagnosis of heparin-induced thrombocytopenia | Journal of Thrombosis and Haemostasis | 2010 | 33 |
| Canadian Registry of ICD Implant Testing procedures (CREDIT): current practice, risks, and costs of intraoperative defibrillation testing | Journal of Cardiovascular Electrophysiology | 2010 | 32 |
| Misleading hepatitis B test results due to intravenous immunoglobulin administration: implications for a clinical trial of rituximab in immune thrombocytopenia | Transfusion | 2010 | 32 |
| Biofuel smoke and child anemia in 29 developing countries: a multilevel analysis | Annals of Epidemiology | 2010 | 30 |
| A scoping review of strategies for the prevention of hip fracture in elderly nursing home residents | PLoS ONE | 2010 | 30 |
