Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency | Nature Genetics | 1999 | 1.5K |
Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides | Brain Research | 1999 | 705 |
Homocyst(e)ine and cardiovascular disease: a critical review of the epidemiologic evidence | Annals of Internal Medicine | 1999 | 627 |
Differential sorting of nerve growth factor and brain-derived neurotrophic factor in hippocampal neurons | Journal of Neuroscience | 1999 | 272 |
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization | Proceedings of the National Academy of Sciences of the United States of America | 1999 | 241 |
Direct evidence for thymic function in adult humans | Journal of Experimental Medicine | 1999 | 196 |
Functional antagonism of the Polycomb-Group genes eed and Bmi1 in hemopoietic cell proliferation | Genes and Development | 1999 | 184 |
Resistance artery mechanics, structure, and extracellular components in spontaneously hypertensive rats : effects of angiotensin receptor antagonism and converting enzyme inhibition | Circulation | 1999 | 183 |
Ang II-stimulated superoxide production is mediated via phospholipase D in human vascular smooth muscle cells | Hypertension | 1999 | 178 |
Involvement of Notch1 in the development of mouse mammary tumors | Oncogene | 1999 | 176 |
Apolipoprotein E and atherosclerosis: insight from animal and human studies | Clinica Chimica Acta | 1999 | 169 |
Low-density lipoprotein-independent effects of statins | Current Opinion in Lipidology | 1999 | 166 |
State-of-the-Art lecture. Role of endothelin-1 in hypertension | Hypertension | 1999 | 163 |
The opioid mu agonist/delta antagonist DIPP-NH(2)[Psi] produces a potent analgesic effect, no physical dependence, and less tolerance than morphine in rats | Journal of Medicinal Chemistry | 1999 | 159 |
Mechanics and composition of human subcutaneous resistance arteries in essential hypertension | Hypertension | 1999 | 149 |
Role of AT2 receptors in angiotensin II-stimulated contraction of small mesenteric arteries in young SHR | Hypertension | 1999 | 136 |
Detection, quantification, and characterization of potentially atherogenic triglyceride-rich remnant lipoproteins | Arteriosclerosis, Thrombosis, and Vascular Biology | 1999 | 133 |
Mitogen-activated protein/extracellular signal-regulated kinase inhibition attenuates angiotensin II-mediated signaling and contraction in spontaneously hypertensive rat vascular smooth muscle cells | Circulation Research | 1999 | 131 |
The subtilisin/kexin family of precursor convertases. Emphasis on PC1, PC2/7B2, POMC and the novel enzyme SKI-1 | Annals of the New York Academy of Sciences | 1999 | 112 |
The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity | Journal of Biological Chemistry | 1999 | 112 |
Apolipoprotein E and beta-amyloid levels in the hippocampus and frontal cortex of Alzheimer's disease subjects are disease-related and apolipoprotein E genotype dependent | Brain Research | 1999 | 112 |
Role of extracellular signal-regulated kinases in angiotensin II-stimulated contraction of smooth muscle cells from human resistance arteries | Circulation | 1999 | 104 |
Angiotensin II stimulates DNA and protein synthesis in vascular smooth muscle cells from human arteries: role of extracellular signal-regulated kinases | Journal of Hypertension | 1999 | 91 |
In vivo study of AT(1) and AT(2) angiotensin receptors in apoptosis in rat blood vessels | Hypertension | 1999 | 86 |
Physiological evidence that the 'interphase' in the formalin test is due to active inhibition | Pain | 1999 | 86 |