PRDM16 controls a brown fat/skeletal muscle switch | Nature | 2008 | 1.6K |
Improving the reporting of pragmatic trials: an extension of the CONSORT statement | BMJ, The | 2008 | 1.1K |
A comparison of aprotinin and lysine analogues in high-risk cardiac surgery | New England Journal of Medicine | 2008 | 883 |
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response | Nature | 2008 | 746 |
Healthcare professionals' intentions and behaviours: a systematic review of studies based on social cognitive theories | Implementation Science | 2008 | 585 |
NADPH oxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities | Diabetes Care | 2008 | 520 |
Niche regulation of muscle satellite cell self-renewal and differentiation | Cell Stem Cell | 2008 | 368 |
SirT1 regulates energy metabolism and response to caloric restriction in mice | PLoS ONE | 2008 | 355 |
K2D2: estimation of protein secondary structure from circular dichroism spectra | BMC Structural Biology | 2008 | 306 |
Epidemiologic evidence of relationships between reproductive and child health outcomes and environmental chemical contaminants | Journal of Toxicology and Environmental Health - Part B: Critical Reviews | 2008 | 305 |
Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration | Experimental Neurology | 2008 | 282 |
Pax7 activates myogenic genes by recruitment of a histone methyltransferase complex | Nature Cell Biology | 2008 | 276 |
SirT1 inhibition reduces IGF-I/IRS-2/Ras/ERK1/2 signaling and protects neurons | Cell Metabolism | 2008 | 274 |
Overdiagnosis of asthma in obese and nonobese adults | Cmaj | 2008 | 264 |
The emerging biology of satellite cells and their therapeutic potential | Trends in Molecular Medicine | 2008 | 253 |
A systematic review of perceived risks, psychological and behavioral impacts of genetic testing | Genetics in Medicine | 2008 | 251 |
Translational control of the innate immune response through IRF-7 | Nature | 2008 | 249 |
Multiple system atrophy: a primary oligodendrogliopathy | Annals of Neurology | 2008 | 239 |
Alendronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women | The Cochrane Library | 2008 | 224 |
Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 206 |
GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 205 |
Health research funding agencies' support and promotion of knowledge translation: an international study | Milbank Quarterly | 2008 | 199 |
Functional interactions between dopamine, serotonin and norepinephrine neurons: an in-vivo electrophysiological study in rats with monoaminergic lesions | International Journal of Neuropsychopharmacology | 2008 | 198 |
The vanishing nonforensic autopsy | New England Journal of Medicine | 2008 | 193 |
The OPALS Major Trauma Study: impact of advanced life-support on survival and morbidity | Cmaj | 2008 | 180 |