Fibrosis stage is the strongest predictor for disease-specific mortality in NAFLD after up to 33 years of follow-up | Hepatology | 2015 | 1.2K |
Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial | Lancet, The | 2015 | 926 |
Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis | JAMA - Journal of the American Medical Association | 2015 | 842 |
Long-term culture of genome-stable bipotent stem cells from adult human liver | Cell | 2015 | 830 |
Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents | Cancer Cell | 2015 | 828 |
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting | Journal of Extracellular Vesicles | 2015 | 711 |
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015 | Cell Death and Differentiation | 2015 | 643 |
Grazoprevir plus elbasvir in treatment-naive and treatment-experienced patients with hepatitis C virus genotype 1 infection and stage 4-5 chronic kidney disease (the C-SURFER study): a combination phase 3 study | Lancet, The | 2015 | 539 |
The promise and peril of chemical probes | Nature Chemical Biology | 2015 | 523 |
Towards tuberculosis elimination: an action framework for low-incidence countries | European Respiratory Journal | 2015 | 462 |
Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function | Immunity | 2015 | 454 |
Inflammation and plaque vulnerability | Journal of Internal Medicine | 2015 | 422 |
The role of vascular biomarkers for primary and secondary prevention. A position paper from the European Society of Cardiology Working Group on peripheral circulation: Endorsed by the Association for Research into Arterial Structure and Physiology (ARTERY) Society | Atherosclerosis | 2015 | 420 |
Cardiovascular risk in post-myocardial infarction patients: nationwide real world data demonstrate the importance of a long-term perspective | European Heart Journal | 2015 | 418 |
Guidelines on Testicular Cancer: 2015 Update | European Urology | 2015 | 398 |
Management of latent Mycobacterium tuberculosis infection: WHO guidelines for low tuberculosis burden countries | European Respiratory Journal | 2015 | 353 |
Diet low in FODMAPs reduces symptoms of irritable bowel syndrome as well as traditional dietary advice: a randomized controlled trial | Gastroenterology | 2015 | 337 |
Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis | Lancet Neurology, The | 2015 | 328 |
Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1 | American Journal of Medical Genetics, Part A | 2015 | 321 |
Clinical and inflammatory characteristics of the European U-BIOPRED adult severe asthma cohort | European Respiratory Journal | 2015 | 292 |
A review of the evolution of systemic chemotherapy in the management of colorectal cancer | Clinical Colorectal Cancer | 2015 | 289 |
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer | JAMA - Journal of the American Medical Association | 2015 | 286 |
EULAR recommendations for the use of imaging in the diagnosis and management of spondyloarthritis in clinical practice | Annals of the Rheumatic Diseases | 2015 | 284 |
European S3-Guidelines on the systemic treatment of psoriasis vulgaris--Update 2015--Short version--EDF in cooperation with EADV and IPC | Journal of the European Academy of Dermatology and Venereology | 2015 | 271 |
SF3B1 mutation identifies a distinct subset of myelodysplastic syndrome with ring sideroblasts | Blood | 2015 | 269 |