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1Improved Survival with Ipilimumab in Patients with Metastatic MelanomaNew England Journal of Medicine201013,065
2Surviving Sepsis CampaignCritical Care Medicine20136,362
3Revised American Thyroid Association Management Guidelines for Patients with Thyroid Nodules and Differentiated Thyroid CancerThyroid20096,039
4The metabolic syndromeLancet, The20055,212
5Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
6The Effect of Carvedilol on Morbidity and Mortality in Patients with Chronic Heart FailureNew England Journal of Medicine19964,294
7Neuroinflammation in Alzheimer's diseaseLancet Neurology, The20154,129
8Biological properties of extracellular vesicles and their physiological functionsJournal of Extracellular Vesicles20153,973
9Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,122
10Survival in Patients with Primary Pulmonary HypertensionAnnals of Internal Medicine19913,050
11Immunological and Inflammatory Functions of the Interleukin-1 FamilyAnnual Review of Immunology20092,831
12Prevalence of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2014MMWR Surveillance Summaries20182,687
13A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary HypertensionNew England Journal of Medicine19962,529
14Age-predicted maximal heart rate revisitedJournal of the American College of Cardiology20012,517
15Fools Rush in? The Institutional Context of Industry CreationAcademy of Management Review19942,480
16Intramuscular interferon beta‐1a for disease progression in relapsing multiple sclerosisAnnals of Neurology19962,365
17Ranibizumab and Bevacizumab for Neovascular Age-Related Macular DegenerationNew England Journal of Medicine20112,355
18Peripheral Arterial Disease Detection, Awareness, and Treatment in Primary CareJAMA - Journal of the American Medical Association20012,332
19Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 DiabetesNew England Journal of Medicine20132,294
20Obesity and Metabolic Syndrome in Circadian Clock Mutant MiceScience20052,181
21Management of Postoperative Pain: A Clinical Practice Guideline From the American Pain Society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists' Committee on Regional Anesthesia, Executive Committee, and Administrative CouncilJournal of Pain20162,040
22The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic HyperplasiaNew England Journal of Medicine20031,780
23Adjuvant Nivolumab versus Ipilimumab in Resected Stage III or IV MelanomaNew England Journal of Medicine20171,752
24Customer Switching Behavior in Service Industries: An Exploratory StudyJournal of Marketing19951,723
252013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiativeAnnals of the Rheumatic Diseases20131,705
26Hypoxia and InflammationNew England Journal of Medicine20111,692
27Prophylaxis versus Episodic Treatment to Prevent Joint Disease in Boys with Severe HemophiliaNew England Journal of Medicine20071,681
28The Spectrum of Engagement in HIV Care and its Relevance to Test-and-Treat Strategies for Prevention of HIV InfectionClinical Infectious Diseases20111,677
29Revision of the CEAP classification for chronic venous disorders: Consensus statementJournal of Vascular Surgery20041,627
30“Economic man” in cross-cultural perspective: Behavioral experiments in 15 small-scale societiesBehavioral and Brain Sciences20051,625
31Nephrectomy Followed by Interferon Alfa-2b Compared with Interferon Alfa-2b Alone for Metastatic Renal-Cell CancerNew England Journal of Medicine20011,583
32Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of GlioblastomaCancer Cell20121,551
33Customer Switching Behavior in Service Industries: An Exploratory StudyJournal of Marketing19951,534
34The Metabolic SyndromeEndocrine Reviews20081,513
35Treating inflammation by blocking interleukin-1 in a broad spectrum of diseasesNature Reviews Drug Discovery20121,479
36Costly Punishment Across Human SocietiesScience20061,445
37Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1Autophagy20211,430
38Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trialLancet Oncology, The20151,419
39Reduction in Weight and Cardiovascular Disease Risk Factors in Individuals With Type 2 DiabetesDiabetes Care20071,369
40Continuous Glucose Monitoring and Intensive Treatment of Type 1 DiabetesNew England Journal of Medicine20081,369
41Ceritinib inALK-Rearranged Non–Small-Cell Lung CancerNew England Journal of Medicine20141,367
42Is Anybody out There? Antecedents of Trust in Global Virtual TeamsJournal of Management Information Systems19981,362
43A Randomized Trial of Aspirin to Prevent Colorectal AdenomasNew England Journal of Medicine20031,358
44Predicting Survival in Pulmonary Arterial HypertensionCirculation20101,353
45State of Type 1 Diabetes Management and Outcomes from the T1D Exchange in 2016–2018Diabetes Technology and Therapeutics20191,332
46Cellular and molecular pathobiology of pulmonary arterial hypertensionJournal of the American College of Cardiology20041,322
47Prevalence and Characteristics of Autism Spectrum Disorder Among Children Aged 8 Years — Autism and Developmental Disabilities Monitoring Network, 11 Sites, United States, 2012MMWR Surveillance Summaries20161,306
48Update of the LIPID MAPS comprehensive classification system for lipidsJournal of Lipid Research20091,300
49Evolutionary and Biomedical Insights from the Rhesus Macaque GenomeScience20071,283
50Identification of a Gene That Causes Primary Open Angle GlaucomaScience19971,274