Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial | Circulation | 2012 | 409 |
Empagliflozin, a novel selective sodium glucose cotransporter-2 (SGLT-2) inhibitor: characterisation and comparison with other SGLT-2 inhibitors | Diabetes, Obesity and Metabolism | 2012 | 384 |
Diagnosis and treatment of patients with stroke in a mobile stroke unit versus in hospital: a randomised controlled trial | Lancet Neurology, The | 2012 | 330 |
Myocardial ischemic events in patients with atrial fibrillation treated with dabigatran or warfarin in the RE-LY (Randomized Evaluation of Long-Term Anticoagulation Therapy) trial | Circulation | 2012 | 306 |
Cardiac biomarkers are associated with an increased risk of stroke and death in patients with atrial fibrillation: a Randomized Evaluation of Long-term Anticoagulation Therapy (RE-LY) substudy | Circulation | 2012 | 291 |
2-year efficacy and safety of linagliptin compared with glimepiride in patients with type 2 diabetes inadequately controlled on metformin: a randomised, double-blind, non-inferiority trial | Lancet, The | 2012 | 278 |
Using the HEMOCLOT direct thrombin inhibitor assay to determine plasma concentrations of dabigatran | Blood Coagulation and Fibrinolysis | 2012 | 228 |
Cardiovascular safety with linagliptin in patients with type 2 diabetes mellitus: a pre-specified, prospective, and adjudicated meta-analysis of a phase 3 programme | Cardiovascular Diabetology | 2012 | 188 |
Dabigatran etexilate for stroke prevention in patients with atrial fibrillation: resolving uncertainties in routine practice | Thrombosis and Haemostasis | 2012 | 169 |
A phase II study of afatinib (BIBW 2992), an irreversible ErbB family blocker, in patients with HER2-positive metastatic breast cancer progressing after trastuzumab | Breast Cancer Research and Treatment | 2012 | 166 |
Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options--a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference | Europace | 2012 | 156 |
Oral apremilast in the treatment of active psoriatic arthritis: results of a multicenter, randomized, double-blind, placebo-controlled study | Arthritis and Rheumatism | 2012 | 151 |
A comparison of dabigatran etexilate with warfarin in patients with mechanical heart valves: THE Randomized, phase II study to evaluate the safety and pharmacokinetics of oral dabigatran etexilate in patients after heart valve replacement (RE-ALIGN) | American Heart Journal | 2012 | 139 |
Efficient chiral monophosphorus ligands for asymmetric Suzuki-Miyaura coupling reactions | Organic Letters | 2012 | 122 |
Initial combination of linagliptin and metformin improves glycaemic control in type 2 diabetes: a randomized, double-blind, placebo-controlled study | Diabetes, Obesity and Metabolism | 2012 | 115 |
Exacerbation frequency and course of COPD | International Journal of COPD | 2012 | 109 |
Patients' preferences for treatment outcomes for advanced non-small cell lung cancer: a conjoint analysis | Lung Cancer | 2012 | 108 |
Variation in warfarin dose adjustment practice is responsible for differences in the quality of anticoagulation control between centers and countries: an analysis of patients receiving warfarin in the randomized evaluation of long-term anticoagulation therapy (RE-LY) trial | Circulation | 2012 | 108 |
Treatment of hypoactive sexual desire disorder in premenopausal women: efficacy of flibanserin in the VIOLET Study | Journal of Sexual Medicine | 2012 | 106 |
Treatment of hypoactive sexual desire disorder in premenopausal women: efficacy of flibanserin in the DAISY study | Journal of Sexual Medicine | 2012 | 102 |
Afatinib pharmacokinetics and metabolism after oral administration to healthy male volunteers | Cancer Chemotherapy and Pharmacology | 2012 | 102 |
The Eight Criteria Defining a Good Chemical Manufacturing Process | Organic Process Research and Development | 2012 | 95 |
Cost-effectiveness of dabigatran etexilate for the prevention of stroke and systemic embolism in UK patients with atrial fibrillation | Heart | 2012 | 91 |
JAK-2 as a novel mediator of the profibrotic effects of transforming growth factor β in systemic sclerosis | Arthritis and Rheumatism | 2012 | 89 |
Linagliptin monotherapy provides superior glycaemic control versus placebo or voglibose with comparable safety in Japanese patients with type 2 diabetes: a randomized, placebo and active comparator-controlled, double-blind study | Diabetes, Obesity and Metabolism | 2012 | 88 |