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PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma | New England Journal of Medicine | 2015 | 2.5K |
The consensus molecular subtypes of colorectal cancer | Nature Medicine | 2015 | 2.3K |
Transfusion of plasma, platelets, and red blood cells in a 1:1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: the PROPPR randomized clinical trial | JAMA - Journal of the American Medical Association | 2015 | 1.3K |
Criteria for the Research Institute for Fragrance Materials, Inc. (RIFM) safety evaluation process for fragrance ingredients | Food and Chemical Toxicology | 2015 | 1.1K |
Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci | Neuron | 2015 | 806 |
Macrophages and therapeutic resistance in cancer | Cancer Cell | 2015 | 786 |
Colorectal cancer | Nature Reviews Disease Primers | 2015 | 684 |
Multiplex single cell profiling of chromatin accessibility by combinatorial cellular indexing | Science | 2015 | 668 |
Effect of Laparoscopic-Assisted Resection vs Open Resection of Stage II or III Rectal Cancer on Pathologic Outcomes: The ACOSOG Z6051 Randomized Clinical Trial | JAMA - Journal of the American Medical Association | 2015 | 666 |
Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis | New England Journal of Medicine | 2015 | 619 |
Ghrelin | Molecular Metabolism | 2015 | 588 |
Quantitative optical coherence tomography angiography of vascular abnormalities in the living human eye | Proceedings of the National Academy of Sciences of the United States of America | 2015 | 474 |
Cell-free DNA analysis for noninvasive examination of trisomy | New England Journal of Medicine | 2015 | 470 |
Brentuximab vedotin as consolidation therapy after autologous stem-cell transplantation in patients with Hodgkin's lymphoma at risk of relapse or progression (AETHERA): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet, The | 2015 | 462 |
Systematic literature review of imaging features of spinal degeneration in asymptomatic populations | American Journal of Neuroradiology | 2015 | 461 |
Gastrointestinal dysfunction in Parkinson's disease | Lancet Neurology, The | 2015 | 436 |
Society for Vascular Surgery practice guidelines for atherosclerotic occlusive disease of the lower extremities: management of asymptomatic disease and claudication | Journal of Vascular Surgery | 2015 | 420 |
Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma | JAMA Ophthalmology | 2015 | 418 |
The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology | Physiological Reviews | 2015 | 376 |
Cortical Membrane Potential Signature of Optimal States for Sensory Signal Detection | Neuron | 2015 | 375 |
International retrospective study of the pipeline embolization device: a multicenter aneurysm treatment study | American Journal of Neuroradiology | 2015 | 365 |
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Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial | Lancet Oncology, The | 2015 | 360 |
B cell follicle sanctuary permits persistent productive simian immunodeficiency virus infection in elite controllers | Nature Medicine | 2015 | 353 |