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1The Cochrane Collaboration's tool for assessing risk of bias in randomised trialsBMJ: British Medical Journal201123,287
2Statistical analysis of cointegration vectorsJournal of Economic Dynamics and Control198813,109
3STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasetsNucleic Acids Research201912,237
4Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2Nature Biotechnology201911,167
5A human gut microbial gene catalogue established by metagenomic sequencingNature20109,342
6STRING v10: protein–protein interaction networks, integrated over the tree of lifeNucleic Acids Research20159,029
8Planetary boundaries: Guiding human development on a changing planetScience20157,124
9New method for quantitative determination of uronic acidsAnalytical Biochemistry19736,487
10The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessibleNucleic Acids Research20176,303
11Enterotypes of the human gut microbiomeNature20115,800
12Stable isotopes in precipitationTellus20225,642
13A metagenome-wide association study of gut microbiota in type 2 diabetesNature20125,345
14Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Autophagy20164,701
15Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteriaLancet Neurology, The20184,605
16Trastuzumab after Adjuvant Chemotherapy in HER2-Positive Breast CancerNew England Journal of Medicine20054,601
17SPIRIT 2013 Statement: Defining Standard Protocol Items for Clinical TrialsAnnals of Internal Medicine20134,463
18The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement setsNucleic Acids Research20214,274
19Sample Size in Qualitative Interview StudiesQualitative Health Research20164,227
20Stable isotopes in precipitationTellus19644,147
21Evidence for general instability of past climate from a 250-kyr ice-core recordNature19934,111
22Dapagliflozin in Patients with Heart Failure and Reduced Ejection FractionNew England Journal of Medicine20194,108
23From game design elements to gamefulness20114,081
24Multifactorial Intervention and Cardiovascular Disease in Patients with Type 2 DiabetesNew England Journal of Medicine20033,894
25Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular FunctionsScience20093,883
26Planetary Boundaries: Exploring the Safe Operating Space for HumanityEcology and Society20093,867
27Standardised Nordic questionnaires for the analysis of musculoskeletal symptomsApplied Ergonomics19873,769
28Richness of human gut microbiome correlates with metabolic markersNature20133,641
29Assessing the Performance of Prediction ModelsEpidemiology20103,387
30SignalP 5.0 improves signal peptide predictions using deep neural networksNature Biotechnology20193,317
31Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell killJournal of Immunological Methods19893,265
32The Danish National Patient RegisterScandinavian Journal of Public Health20113,237
33Guidelines for the use and interpretation of assays for monitoring autophagyAutophagy20123,122
34PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKa PredictionsJournal of Chemical Theory and Computation20113,121
35The STRING database in 2011: functional interaction networks of proteins, globally integrated and scoredNucleic Acids Research20113,014
36The size and burden of mental disorders and other disorders of the brain in Europe 2010European Neuropsychopharmacology20112,930
37Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral MicrodialysisJournal of Neurochemistry19842,872
38Antibiotic resistance of bacterial biofilmsInternational Journal of Antimicrobial Agents20102,809
39Assembly, configuration, and break-up history of Rodinia: A synthesisPrecambrian Research20082,747
40The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selectionAnnals of the Rheumatic Diseases20092,713
41Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015Journal of the American College of Cardiology20172,705
42Iolite: Freeware for the visualisation and processing of mass spectrometric dataJournal of Analytical Atomic Spectrometry20112,629
43eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 virusesNucleic Acids Research20192,575
44Interpreting the Clinical Importance of Treatment Outcomes in Chronic Pain Clinical Trials: IMMPACT RecommendationsJournal of Pain20082,564
45The Physiology of Glucagon-like Peptide 1Physiological Reviews20072,504
46DNA damage response as a candidate anti-cancer barrier in early human tumorigenesisNature20052,491
47High-resolution record of Northern Hemisphere climate extending into the last interglacial periodNature20042,489
48The Microbial Engines That Drive Earth's Biogeochemical CyclesScience20082,449
49Cross-Validation of Item Selection and Scoring for the SF-12 Health Survey in Nine CountriesJournal of Clinical Epidemiology19982,428
50Global Iron Connections Between Desert Dust, Ocean Biogeochemistry, and ClimateScience20052,365