14.3K(top 2%)
PR articles
434.8K(top 2%)
PR citations
239(top 1%)
PR h-index
275(top 1%)
h-index
18.2K
documents
621.0K
doc citations
19.5K
citing journals
awards

Top Articles

#TitleJournalYearCitations
1Classification and natural history of clinically identifiable subtypes of cerebral infarctionLancet, The19912,308
2Revised International Prognostic Scoring System for Myelodysplastic SyndromesBlood20122,275
3Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trialLancet, The20052,235
4EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer—2020 Update. Part 1: Screening, Diagnosis, and Local Treatment with Curative IntentEuropean Urology20212,224
5Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processingNature Genetics20192,127
6Liraglutide safety and efficacy in patients with non-alcoholic steatohepatitis (LEAN): a multicentre, double-blind, randomised, placebo-controlled phase 2 studyLancet, The20161,645
7A Phase 3 Trial of Bevacizumab in Ovarian CancerNew England Journal of Medicine20111,618
8EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthoodNature Reviews Clinical Oncology20201,606
9MicroRNAs in cancer: biomarkers, functions and therapyTrends in Molecular Medicine20141,496
10Global Prevalence of and Risk Factors for Irritable Bowel Syndrome: A Meta-analysisClinical Gastroenterology and Hepatology20121,435
11Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trialLancet, The20171,431
12ECCO-ESGAR Guideline for Diagnostic Assessment in IBD Part 1: Initial diagnosis, monitoring of known IBD, detection of complications.Journal of Crohn's and Colitis20191,418
13A Comparison of Multimodal Therapy and Surgery for Esophageal AdenocarcinomaNew England Journal of Medicine19961,375
14World guidelines for falls prevention and management for older adults: a global initiative.Age and Ageing20221,298
15Risks of cancer in BRCA1-mutation carriersLancet, The19941,294
16Management of frailty: opportunities, challenges, and future directionsLancet, The20191,294
17An SCN9A channelopathy causes congenital inability to experience painNature20061,159
18EAU-EANM-ESTRO-ESUR-ISUP-SIOG Guidelines on Prostate Cancer—2024 Update. Part I: Screening, Diagnosis, and Local Treatment with Curative IntentEuropean Urology20241,143
19Connexin 26 mutations in hereditary non-syndromic sensorineural deafnessNature19971,121
20Randomized Trial of Laparoscopic-Assisted Resection of Colorectal Carcinoma: 3-Year Results of the UK MRC CLASICC Trial GroupJournal of Clinical Oncology20071,091
21Primary chemotherapy versus primary surgery for newly diagnosed advanced ovarian cancer (CHORUS): an open-label, randomised, controlled, non-inferiority trialLancet, The20151,063
22Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trialLancet, The20091,020
23Guidelines for enhanced recovery after lung surgery: recommendations of the Enhanced Recovery After Surgery (ERAS®) Society and the European Society of Thoracic Surgeons (ESTS)European Journal of Cardio-thoracic Surgery20191,012
24International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumoniaEuropean Respiratory Journal20171,003
25Official ERS/ATS clinical practice guidelines: noninvasive ventilation for acute respiratory failure.European Respiratory Journal2017976
26Measuring quality of life in routine oncology practice improves communication and patient well-being: a randomized controlled trial.Journal of Clinical Oncology2004966
27Piezo1 integration of vascular architecture with physiological forceNature2014949
28Five-Year Outcomes With Pembrolizumab Versus Chemotherapy for Metastatic Non-Small-Cell Lung Cancer With PD-L1 Tumor Proportion Score ≥ 50.Journal of Clinical Oncology2021940
29Molecular biology of bladder cancer: new insights into pathogenesis and clinical diversityNature Reviews Cancer2014920
30Recommendations for reporting tumor budding in colorectal cancer based on the International Tumor Budding Consensus Conference (ITBCC) 2016Modern Pathology2017871
31Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorderNature Genetics2008870
32New method for detecting slime production by coagulase negative staphylococci.Journal of Clinical Pathology1989818
33EAU-EANM-ESTRO-ESUR-SIOG Guidelines on Prostate Cancer. Part II—2020 Update: Treatment of Relapsing and Metastatic Prostate CancerEuropean Urology2021812
34Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunityNature Genetics2012778
35A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitisJournal of Experimental Medicine2013774
36British Thoracic Society guidelines for the investigation and management of pulmonary nodules: accredited by NICEThorax2015744
37Prevalence and Outcomes of Infection Among Patients in Intensive Care Units in 2017JAMA - Journal of the American Medical Association2020730
38Early use of non-invasive ventilation for acute exacerbations of chronic obstructive pulmonary disease on general respiratory wards: a multicentre randomised controlled trialLancet, The2000729
39Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic LeukemiaNew England Journal of Medicine2016713
40Postoperative pulmonary complicationsBritish Journal of Anaesthesia2017713
41A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serumScientific Reports2020708
42Five-year follow-up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer.British Journal of Surgery2010704
43Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutières syndrome at the AGS1 locusNature Genetics2006702
44Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trialLancet, The2009701
45Change in stroke incidence, mortality, case-fatality, severity, and risk factors in Oxfordshire, UK from 1981 to 2004 (Oxford Vascular Study)Lancet, The2004700
46Addition of cetuximab to oxaliplatin-based first-line combination chemotherapy for treatment of advanced colorectal cancer: results of the randomised phase 3 MRC COIN trialLancet, The2011673
47Current concepts of molecular aspects of bone healingInjury2005662
48Global prevalence of irritable bowel syndrome according to Rome III or IV criteria: a systematic review and meta-analysisThe Lancet Gastroenterology and Hepatology2020653
49Targeting Toll-like receptors: emerging therapeutics?Nature Reviews Drug Discovery2010640
50Probiotic Bifidobacterium longum NCC3001 Reduces Depression Scores and Alters Brain Activity: A Pilot Study in Patients With Irritable Bowel SyndromeGastroenterology2017633