Predicting the functional, molecular, and phenotypic consequences of amino acid substitutions using hidden Markov models | Human Mutation | 2013 | 723 |
HOTAIR is a negative prognostic factor and exhibits pro-oncogenic activity in pancreatic cancer | Oncogene | 2013 | 656 |
Beyond GWASs: illuminating the dark road from association to function | American Journal of Human Genetics | 2013 | 515 |
The RASopathies | Annual Review of Genomics and Human Genetics | 2013 | 481 |
Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches | Oncogene | 2013 | 466 |
Senescence and aging: the critical roles of p53 | Oncogene | 2013 | 459 |
dbNSFP v2.0: a database of human non-synonymous SNVs and their functional predictions and annotations | Human Mutation | 2013 | 455 |
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation | Oncogene | 2013 | 424 |
Mitochondrial dynamics regulates migration and invasion of breast cancer cells | Oncogene | 2013 | 411 |
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies | Oncogene | 2013 | 391 |
Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity | Oncogene | 2013 | 388 |
Where genotype is not predictive of phenotype: towards an understanding of the molecular basis of reduced penetrance in human inherited disease | Human Genetics | 2013 | 384 |
RFMix: a discriminative modeling approach for rapid and robust local-ancestry inference | American Journal of Human Genetics | 2013 | 384 |
Major histocompatibility complex genomics and human disease | Annual Review of Genomics and Human Genetics | 2013 | 381 |
JAK/STAT signaling in hematological malignancies | Oncogene | 2013 | 346 |
Detection of clinically relevant genetic variants in autism spectrum disorder by whole-genome sequencing | American Journal of Human Genetics | 2013 | 345 |
Leukemia cell to endothelial cell communication via exosomal miRNAs | Oncogene | 2013 | 342 |
Bardet-Biedl syndrome | European Journal of Human Genetics | 2013 | 330 |
Epigenome-wide association study in the European Prospective Investigation into Cancer and Nutrition (EPIC-Turin) identifies novel genetic loci associated with smoking | Human Molecular Genetics | 2013 | 319 |
Actionable, pathogenic incidental findings in 1,000 participants' exomes | American Journal of Human Genetics | 2013 | 302 |
Sequence kernel association tests for the combined effect of rare and common variants | American Journal of Human Genetics | 2013 | 300 |
Improved detection of common variants associated with schizophrenia by leveraging pleiotropy with cardiovascular-disease risk factors | American Journal of Human Genetics | 2013 | 293 |
Meta-analysis of telomere length in 19,713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect | European Journal of Human Genetics | 2013 | 291 |
Universal heteroplasmy of human mitochondrial DNA | Human Molecular Genetics | 2013 | 278 |
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas | Oncogene | 2013 | 277 |