14,350
Journals
25.7M
Articles
508.6M
Citations
2.1M
Authors

Most Cited Articles of Health Sciences in 2001

TitleJournalYearCitations
Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III)JAMA - Journal of the American Medical Association200121.5K
The PHQ-9: validity of a brief depression severity measureJournal of General Internal Medicine200119.7K
Intensive insulin therapy in critically ill patientsNew England Journal of Medicine200112.3K
Frailty in older adults: evidence for a phenotypeJournals of Gerontology - Series A Biological Sciences and Medical Sciences200111.9K
Early goal-directed therapy in the treatment of severe sepsis and septic shockNew England Journal of Medicine200110.7K
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2New England Journal of Medicine20018.7K
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settingsAdvanced Drug Delivery Reviews20018.6K
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose toleranceNew England Journal of Medicine20017.6K
The role of positive emotions in positive psychology: The broaden-and-build theory of positive emotions.American Psychologist20017.3K
Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of careCritical Care Medicine20017K
Efficacy and safety of recombinant human activated protein C for severe sepsisNew England Journal of Medicine20016.9K
A new statistical method for haplotype reconstruction from population dataAmerican Journal of Human Genetics20016.3K
Inflammation and cancer: back to Virchow?Lancet, The20015.6K
Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathyNew England Journal of Medicine20015.5K
Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosisAnnals of Neurology20015.4K
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trialLancet, The20015.3K
Interleukin-10 and the interleukin-10 receptorAnnual Review of Immunology20015K
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevationNew England Journal of Medicine20015K
Alzheimer's disease: genes, proteins, and therapyPhysiological Reviews20014.9K
A global optimisation method for robust affine registration of brain imagesMedical Image Analysis20014.7K
Modular chemistry: secondary building units as a basis for the design of highly porous and robust metal-organic carboxylate frameworksAccounts of Chemical Research20014.6K
Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) StudyJAMA - Journal of the American Medical Association20014.4K
Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetesNew England Journal of Medicine20014.4K
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summaryAmerican Journal of Respiratory and Critical Care Medicine20014.4K
Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithmIEEE Transactions on Medical Imaging20014.3K