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Most Cited Articles of Metabolic Engineering in 2020

TitleJournalYearCitations
Metabolic engineering advances and prospects for amino acid productionMetabolic Engineering202086
Engineering biosynthesis of polyhydroxyalkanoates (PHA) for diversity and cost reductionMetabolic Engineering202076
Metabolic engineering for the synthesis of polyesters: A 100-year journey from polyhydroxyalkanoates to non-natural microbial polyestersMetabolic Engineering202074
Engineering 4-coumaroyl-CoA derived polyketide production in Yarrowia lipolytica through a β-oxidation mediated strategyMetabolic Engineering202070
CRISPR/Cas9 directed editing of lycopene epsilon-cyclase modulates metabolic flux for β-carotene biosynthesis in banana fruitMetabolic Engineering202061
The yeast peroxisome: A dynamic storage depot and subcellular factory for squalene overproductionMetabolic Engineering202060
Metabolic engineering for the production of dicarboxylic acids and diaminesMetabolic Engineering202059
CRISPR-Cas12a/Cpf1-assisted precise, efficient and multiplexed genome-editing inMetabolic Engineering Communications202051
In vitro prototyping of limonene biosynthesis using cell-free protein synthesisMetabolic Engineering202043
Coupling metabolic addiction with negative autoregulation to improve strain stability and pathway yieldMetabolic Engineering202042
Adaptive laboratory evolution of KT2440 improves -coumaric and ferulic acid catabolism and toleranceMetabolic Engineering Communications202040
Revisiting metabolic engineering strategies for microbial synthesis of oleochemicalsMetabolic Engineering202040
Development of both type I-B and type II CRISPR/Cas genome editing systems in the cellulolytic bacteriumMetabolic Engineering Communications202038
Modular engineering for microbial production of carotenoidsMetabolic Engineering Communications202038
Debottlenecking mevalonate pathway for antimalarial drug precursor amorphadiene biosynthesis inMetabolic Engineering Communications202038
Total in vitro biosynthesis of the nonribosomal macrolactone peptide valinomycinMetabolic Engineering202035
Building microbial factories for the production of aromatic amino acid pathway derivatives: From commodity chemicals to plant-sourced natural productsMetabolic Engineering202034
Engineering glucose metabolism for enhanced muconic acid production in Pseudomonas putida KT2440Metabolic Engineering202033
Enhancing isoprenoid synthesis in Yarrowia lipolytica by expressing the isopentenol utilization pathway and modulating intracellular hydrophobicityMetabolic Engineering202033
Replacing the Calvin cycle with the reductive glycine pathway in Cupriavidus necatorMetabolic Engineering202031
A CRISPR/Cas9-based genome editing system for Rhodococcus ruber THMetabolic Engineering202031
Engineering chimeric diterpene synthases and isoprenoid biosynthetic pathways enables high-level production of miltiradiene in yeastMetabolic Engineering202030
A single-host fermentation process for the production of flavor lactones from non-hydroxylated fatty acidsMetabolic Engineering202030
Engineering the oleaginous yeast Yarrowia lipolytica for high-level resveratrol productionMetabolic Engineering202029
Metabolic engineering of Saccharomyces cerevisiae for the de novo production of psilocybin and related tryptamine derivativesMetabolic Engineering202027