A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding | Analytical Biochemistry | 1976 | 199.3K |
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction | Analytical Biochemistry | 1987 | 56.3K |
QIIME allows analysis of high-throughput community sequencing data | Nature Methods | 2010 | 22.4K |
The hallmarks of cancer | Cell | 2000 | 20.3K |
Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction | Analytical Biochemistry | 1979 | 18.6K |
Features and development of Coot | Acta Crystallographica Section D: Biological Crystallography | 2010 | 16.1K |
PHENIX: a comprehensive Python-based system for macromolecular structure solution | Acta Crystallographica Section D: Biological Crystallography | 2010 | 15.8K |
Crystallography & NMR system: A new software suite for macromolecular structure determination | Acta Crystallographica Section D: Biological Crystallography | 1998 | 14K |
Cluster analysis and display of genome-wide expression patterns | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 12.5K |
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures | Journal of Applied Crystallography | 1991 | 11.7K |
BEDTools: a flexible suite of utilities for comparing genomic features | Bioinformatics | 2010 | 11.5K |
Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I | Journal of Molecular Biology | 1977 | 11.2K |
Molecular portraits of human breast tumours | Nature | 2000 | 10.9K |
Significance analysis of microarrays applied to the ionizing radiation response | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 9.7K |
Improved tools for biological sequence comparison | Proceedings of the National Academy of Sciences of the United States of America | 1988 | 9.5K |
jModelTest 2: more models, new heuristics and parallel computing | Nature Methods | 2012 | 9.5K |
MolProbity: all-atom structure validation for macromolecular crystallography | Acta Crystallographica Section D: Biological Crystallography | 2010 | 9.4K |
Studies on transformation of Escherichia coli with plasmids | Journal of Molecular Biology | 1983 | 9.4K |
Multiplex genome engineering using CRISPR/Cas systems | Science | 2013 | 9.3K |
UCHIME improves sensitivity and speed of chimera detection | Bioinformatics | 2011 | 9.2K |
A method and server for predicting damaging missense mutations | Nature Methods | 2010 | 9.1K |
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification | Nature Biotechnology | 2008 | 8.8K |
Overview of the CCP4 suite and current developments | Acta Crystallographica Section D: Biological Crystallography | 2011 | 8.7K |
Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes | Journal of Molecular Biology | 2001 | 8.7K |
The chemistry of graphene oxide | Chemical Society Reviews | 2010 | 8.5K |