Most Cited Articles of Molecular Biology

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Nature1970226.2K
DNA sequencing with chain-terminating inhibitorsProceedings of the National Academy of Sciences of the United States of America197759.6K
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceNucleic Acids Research199452.1K
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2Genome Biology201426.6K
Clustal W and Clustal X version 2.0Bioinformatics200720.9K
PROCHECK: a program to check the stereochemical quality of protein structuresJournal of Applied Crystallography199317.7K
Initial sequencing and analysis of the human genomeNature200116.8K
Continuous cultures of fused cells secreting antibody of predefined specificityNature197513.9K
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structuresJournal of Applied Crystallography199111.7K
GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular SimulationJournal of Chemical Theory and Computation200811.5K
AutoDock Vina: Improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreadingJournal of Computational Chemistry201011.3K
An integrated encyclopedia of DNA elements in the human genomeNature201211.1K
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibilityJournal of Computational Chemistry200911.1K
Improved methods for building protein models in electron density maps and the location of errors in these modelsActa Crystallographica Section A: Foundations and Advances199111K
Molecular portraits of human breast tumoursNature200010.9K
Development and testing of a general amber force fieldJournal of Computational Chemistry200410.3K
HTSeq--a Python framework to work with high-throughput sequencing dataBioinformatics201510.2K
GROMACS: Fast, flexible, and freeJournal of Computational Chemistry20059.9K
Differential expression analysis for sequence count dataGenome Biology20109.7K
Matrix elasticity directs stem cell lineage specificationCell20069.7K
Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogeneScience19879.3K
A method and server for predicting damaging missense mutationsNature Methods20109.1K
Overview of the CCP4 suite and current developmentsActa Crystallographica Section D: Biological Crystallography20118.7K
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunityScience20128.5K