| Analyzing real-time PCR data by the comparative CT method | Nature Protocols | 2008 | 15.6K |
| All-Atom Empirical Potential for Molecular Modeling and Dynamics Studies of Proteins† | Journal of Physical Chemistry B | 1998 | 11.2K |
| A method for estimating the probability of adverse drug reactions | Clinical Pharmacology and Therapeutics | 1981 | 7.8K |
| CHARMM: The biomolecular simulation program | Journal of Computational Chemistry | 2009 | 5.3K |
| A well-behaved electrostatic potential based method using charge restraints for deriving atomic charges: the RESP model | The Journal of Physical Chemistry | 1993 | 5.1K |
| In situ click chemistry generation of cyclooxygenase-2 inhibitors | Nature Communications | 2017 | 5.1K |
| Validation of open:closed arm entries in an elevated plus-maze as a measure of anxiety in the rat | Journal of Neuroscience Methods | 1985 | 4.1K |
| Cancer chemopreventive activity of resveratrol, a natural product derived from grapes | Science | 1997 | 3.9K |
| Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 3.8K |
| Reproducible, interactive, scalable and extensible microbiome data science using QIIME 2 | Nature Biotechnology | 2019 | 3.7K |
| MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling | Science | 2007 | 3.6K |
| A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability | Pharmaceutical Research | 1995 | 3.4K |
| Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 3.3K |
| Oxidative mechanisms in the toxicity of metal ions | Free Radical Biology and Medicine | 1995 | 3K |
| An all atom force field for simulations of proteins and nucleic acids | Journal of Computational Chemistry | 1986 | 2.9K |
| PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data | Journal of Chemical Theory and Computation | 2013 | 2.9K |
| Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011) | Chemical Reviews | 2014 | 2.9K |
| CHARMM general force field: A force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fields | Journal of Computational Chemistry | 2010 | 2.9K |
| Antiseptics and disinfectants: activity, action, and resistance | Clinical Microbiology Reviews | 1999 | 2.8K |
| Allergic Rhinitis and its Impact on Asthma (ARIA) 2008* | Allergy: European Journal of Allergy and Clinical Immunology | 2008 | 2.8K |
| Quantum dots versus organic dyes as fluorescent labels | Nature Methods | 2008 | 2.8K |
| Extending the treatment of backbone energetics in protein force fields: Limitations of gas-phase quantum mechanics in reproducing protein conformational distributions in molecular dynamics simulations | Journal of Computational Chemistry | 2004 | 2.7K |
| Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 2.7K |
| Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the Gram-negative bacterium Escherichia coli | Applied and Environmental Microbiology | 2007 | 2.7K |
| Beware of q2! | Journal of Molecular Graphics and Modelling | 2002 | 2.7K |
