Most Cited Articles of Biology

Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assaysJournal of Immunological Methods198339.7K
The Sequence Alignment/Map format and SAMtoolsBioinformatics200930K
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2Genome Biology201426.6K
MEGA7: Molecular Evolutionary Genetics Analysis Version 7.0 for Bigger DatasetsMolecular Biology and Evolution201624.2K
Fast gapped-read alignment with Bowtie 2Nature Methods201223.9K
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, ChinaLancet, The202023.9K
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesProceedings of the National Academy of Sciences of the United States of America200523.8K
QIIME allows analysis of high-throughput community sequencing dataNature Methods201022.4K
MAFFT multiple sequence alignment software version 7: improvements in performance and usabilityMolecular Biology and Evolution201318.1K
MRBAYES: Bayesian inference of phylogenetic treesBioinformatics200117.5K
Initial sequencing and analysis of the human genomeNature200116.8K
MicroRNAs: target recognition and regulatory functionsCell200914.8K
Ultrafast and memory-efficient alignment of short DNA sequences to the human genomeGenome Biology200914.3K
MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model SpaceSystematic Biology201213.8K
Introducing mothur: open-source, platform-independent, community-supported software for describing and comparing microbial communitiesApplied and Environmental Microbiology200913.5K
ANALYZING TABLES OF STATISTICAL TESTSEvolution; International Journal of Organic Evolution198912.1K
MEGA X: Molecular Evolutionary Genetics Analysis across Computing PlatformsMolecular Biology and Evolution201811.8K
Full-length transcriptome assembly from RNA-Seq data without a reference genomeNature Biotechnology201111.5K
SPAdes: a new genome assembly algorithm and its applications to single-cell sequencingJournal of Computational Biology201211.4K
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nucleiNucleic Acids Research198311.2K
An integrated encyclopedia of DNA elements in the human genomeNature201211.1K
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegansNature199811K
HTSeq--a Python framework to work with high-throughput sequencing dataBioinformatics201510.2K
The sequence of the human genomeScience200110.2K
Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiationNature Biotechnology201010K