70(top 5%)
PR articles
11.8K(top 1%)
PR citations
41(top 1%)
PR h-index
42(top 2%)
h-index
75
documents
15.2K
doc citations
2.2K
citing journals
100
times ranked

Publications

71 peer-reviewed articles • 12,840 peer-reviewed citations • Sorted by year • Download PDF (PDF by citations)
Sort: Year | Citations
#ArticleIFCitationsLinks
1Light‐Activated Reactivity of Nitrones with Amino Acids and Proteins
Angewandte Chemie, 2025, 137,
1.41Citations (PDF)
2Light‐Activated Reactivity of Nitrones with Amino Acids and Proteins14.44Citations (PDF)
3Enhancing the Small-Scale Screenable Biological Space beyond Known Chemogenomics Libraries with Gray Chemical Matter─Compounds with Novel Mechanisms from High-Throughput Screening Profiles
ACS Chemical Biology, 2024, 19, 938-952
3.75Citations (PDF)
4Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells
ACS Chemical Biology, 2024, 19, 1260-1270
3.78Citations (PDF)
5Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB
Cell Chemical Biology, 2023, 30, 394-402.e9
6.295Citations (PDF)
6Targeted Protein Degradation through E2 Recruitment
ACS Chemical Biology, 2023, 18, 897-904
3.752Citations (PDF)
7Rational Chemical Design of Molecular Glue Degraders
ACS Central Science, 2023, 9, 915-926
9.2173Citations (PDF)
8Activation of human STING by a molecular glue-like compound
Nature Chemical Biology, 2023, 20, 365-372
11.867Citations (PDF)
9A strategy to assess the cellular activity of E3 ligase components against neo-substrates using electrophilic probes
Cell Chemical Biology, 2022, 29, 57-66.e6
6.220Citations (PDF)
10PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer8.531Citations (PDF)
11Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications15.0201Citations (PDF)
12Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design
Chemical Science, 2022, 13, 3851-3856
7.132Citations (PDF)
13Deubiquitinase-targeting chimeras for targeted protein stabilization
Nature Chemical Biology, 2022, 18, 412-421
11.8311Citations (PDF)
14Donor–Acceptor Pyridinium Salts for Photo-Induced Electron-Transfer-Driven Modification of Tryptophan in Peptides, Proteins, and Proteomes Using Visible Light15.072Citations (PDF)
15An Activity-Based Oxaziridine Platform for Identifying and Developing Covalent Ligands for Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 415.035Citations (PDF)
16Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function
Cell Chemical Biology, 2021, 28, 559-566.e15
6.2174Citations (PDF)
17Proteomics in the pharmaceutical and biotechnology industry: a look to the next decade
Expert Review of Proteomics, 2021, 18, 503-526
2.051Citations (PDF)
18Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8
ACS Chemical Biology, 2021, 16, 2185-2192
3.715Citations (PDF)
19BET bromodomain inhibitors regulate keratinocyte plasticity
Nature Chemical Biology, 2021, 17, 280-290
11.812Citations (PDF)
20Discovery of a Functional Covalent Ligand Targeting an Intrinsically Disordered Cysteine within MYC
Cell Chemical Biology, 2021, 28, 4-13.e17
6.2155Citations (PDF)
21Bardoxolone conjugation enables targeted protein degradation of BRD4
Scientific Reports, 2020, 10,
3.4133Citations (PDF)
22A Nimbolide-Based Kinase Degrader Preferentially Degrades Oncogenic BCR-ABL
ACS Chemical Biology, 2020, 15, 1788-1794
3.7109Citations (PDF)
23Manumycin polyketides act as molecular glues between UBR7 and P53
Nature Chemical Biology, 2020, 16, 1189-1198
11.8120Citations (PDF)
24A small-molecule inhibitor of C5 complement protein
Nature Chemical Biology, 2019, 15, 666-668
11.822Citations (PDF)
25Harnessing the anti-cancer natural product nimbolide for targeted protein degradation
Nature Chemical Biology, 2019, 15, 747-755
11.8408Citations (PDF)
26Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications
ACS Chemical Biology, 2019, 14, 2430-2440
3.7323Citations (PDF)
27An Activity‐Based Probe Targeting Non‐Catalytic, Highly Conserved Amino Acid Residues within Bromodomains
Angewandte Chemie, 2019, 131, 1019-1024
1.47Citations (PDF)
28Previously Uncharacterized Vacuolar-type ATPase Binding Site Discovered from Structurally Similar Compounds with Distinct Mechanisms of Action
ACS Chemical Biology, 2019, 14, 20-26
3.715Citations (PDF)
29Discovery of a ZIP7 inhibitor from a Notch pathway screen
Nature Chemical Biology, 2019, 15, 179-188
11.871Citations (PDF)
30CPSF3-dependent pre-mRNA processing as a druggable node in AML and Ewing’s sarcoma
Nature Chemical Biology, 2019, 16, 50-59
11.885Citations (PDF)
31Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells3.438Citations (PDF)
32Direct Interaction of Chivosazole F with Actin Elicits Cell Responses Similar to Latrunculin A but Distinct from Chondramide
ACS Chemical Biology, 2017, 12, 2264-2269
3.710Citations (PDF)
33Examining the influence of specificity ligands and ATP-competitive ligands on the overall effectiveness of bivalent kinase inhibitors
Proteome Science, 2016, 15,
1.67Citations (PDF)
34Tankyrase Inhibitor Sensitizes Lung Cancer Cells to Endothelial Growth Factor Receptor (EGFR) Inhibition via Stabilizing Angiomotins and Inhibiting YAP Signaling
Journal of Biological Chemistry, 2016, 291, 15256-15266
2.277Citations (PDF)
35Conversion of a Single Polypharmacological Agent into Selective Bivalent Inhibitors of Intracellular Kinase Activity
ACS Chemical Biology, 2016, 11, 121-131
3.727Citations (PDF)
36Identifying compound efficacy targets in phenotypic drug discovery
Drug Discovery Today, 2016, 21, 82-89
6.6149Citations (PDF)
37Nannocystin A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti‐Cancer Properties14.4103Citations (PDF)
38Gift from Nature: Cyclomarin A Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action
ChemBioChem, 2015, 16, 2433-2436
2.651Citations (PDF)
39Quantitative Lys-ϵ-Gly-Gly (diGly) Proteomics Coupled with Inducible RNAi Reveals Ubiquitin-mediated Proteolysis of DNA Damage-inducible Transcript 4 (DDIT4) by the E3 Ligase HUWE1
Journal of Biological Chemistry, 2014, 289, 28942-28955
2.273Citations (PDF)
40Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo
Nature Cell Biology, 2014, 16, 1069-1079
16.3729Citations (PDF)
41Target identification for a Hedgehog pathway inhibitor reveals the receptor GPR39
Nature Chemical Biology, 2014, 10, 343-349
11.858Citations (PDF)
42Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide
Nature, 2014, 512, 49-53
37.91,070Citations (PDF)
43Deubiquitinase FAM/USP9X Interacts with the E3 Ubiquitin Ligase SMURF1 Protein and Protects It from Ligase Activity-dependent Self-degradation
Journal of Biological Chemistry, 2013, 288, 2976-2985
2.2114Citations (PDF)
44Mass Spectrometry-Based Proteomics in Preclinical Drug Discovery
Chemistry and Biology, 2012, 19, 72-84
4.7178Citations (PDF)
45Natural products reveal cancer cell dependence on oxysterol-binding proteins
Nature Chemical Biology, 2011, 7, 639-647
11.8257Citations (PDF)
46RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling
Nature Cell Biology, 2011, 13, 623-629
16.3425Citations (PDF)
47Bone Overgrowth-associated Mutations in the LRP4 Gene Impair Sclerostin Facilitator Function
Journal of Biological Chemistry, 2011, 286, 19489-19500
2.2284Citations (PDF)
48Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication
Journal of Virology, 2009, 83, 10058-10074
3.6189Citations (PDF)
49Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling
Nature, 2009, 461, 614-620
37.91,989Citations (PDF)
50Post-translational Tyrosine Nitration of Eosinophil Granule Toxins Mediated by Eosinophil Peroxidase
Journal of Biological Chemistry, 2008, 283, 28629-28640
2.244Citations (PDF)
51Quantitative mass spectrometry in proteomics: a critical review3.41,531Citations (PDF)
52Proteome survey reveals modularity of the yeast cell machinery
Nature, 2006, 440, 631-636
37.92,430Citations (PDF)
53Multiple synergizing factors contribute to the strength of the CD8+ T cell response against listeriolysin O
International Immunology, 2006, 18, 89-100
3.17Citations (PDF)
54Computational prediction of proteotypic peptides for quantitative proteomics
Nature Biotechnology, 2006, 25, 125-131
29.8681Citations (PDF)
55Scoring proteomes with proteotypic peptide probes78.1350Citations (PDF)
56Bartonella Adhesin A Mediates a Proangiogenic Host Cell Response
Journal of Experimental Medicine, 2004, 200, 1267-1278
9.3207Citations (PDF)
57Arf1p Provides an Unexpected Link between COPI Vesicles and mRNA in Saccharomyces cerevisiae
Molecular Biology of the Cell, 2004, 15, 5021-5037
2.547Citations (PDF)
58A physical and functional map of the human TNF-α/NF-κB signal transduction pathway
Nature Cell Biology, 2004, 6, 97-105
16.31,031Citations (PDF)
59A 14-3-3 protein of Chlamydomonas reinhardtii associated with the endoplasmic reticulum: nucleotide sequence of the cDNA and the corresponding gene and derived amino acid sequence3.411Citations (PDF)
60Profiling Core Proteomes of Human Cell Lines by One-dimensional PAGE and Liquid Chromatography-Tandem Mass Spectrometry3.0213Citations (PDF)
61Biosynthese von Glycopeptid-Antibiotika vom Vancomycin-Typ: die Reihenfolge der Ringschlüsse
Angewandte Chemie, 2001, 113, 4824-4827
1.436Citations (PDF)
62The Biosynthesis of Vancomycin-Type Glycopeptide Antibiotics-The Order of the Cyclization Steps14.4141Citations (PDF)
63Dermcidin: a novel human antibiotic peptide secreted by sweat glands
Nature Immunology, 2001, 2, 1133-1137
23.5690Citations (PDF)
64Combining computer algorithms with experimental approaches permits the rapid and accurate identification of T cell epitopes from defined antigens1.490Citations (PDF)
65A Naturally Processed Rat Major Histocompatibility Complex Class I-associated Viral Peptide as Target Structure of Borna Disease Virus-specific CD8+ T Cells
Journal of Biological Chemistry, 2001, 276, 13689-13694
2.224Citations (PDF)
66Identification of tumor-associated MHC class I ligands by a novel T cell-independent approach
European Journal of Immunology, 2000, 30, 2216-2225
3.1133Citations (PDF)
67Two new proteases in the MHC class I processing pathway
Nature Immunology, 2000, 1, 413-418
23.5236Citations (PDF)
68The HLA-A*6601 peptide motif: prediction by pocket structure and verification by peptide analysis
Immunogenetics, 1999, 49, 571-576
2.815Citations (PDF)
69Peptide motif of HLA-B*1510
Immunogenetics, 1999, 49, 996-999
2.86Citations (PDF)
70Contribution of Proteasomal β-Subunits to the Cleavage of Peptide Substrates Analyzed with Yeast Mutants
Journal of Biological Chemistry, 1998, 273, 25637-25646
2.2244Citations (PDF)
71Discovery of EGT710, an Oral Nonpeptidomimetic Reversible Covalent SARS-CoV-2 Main Protease Inhibitor5.60Citations (PDF)