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94 papers • 5,500 citations • Sorted by year • Download PDF (PDF by citations)
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1Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection14.15Citations (PDF)
2Ex Vivo Expanded Cord Blood Natural Killer Cells Combined with Rituximab and High-Dose Chemotherapy and Autologous Stem Cell Transplantation for B Cell Non-Hodgkin Lymphoma
Transplantation and Cellular Therapy, 2024, 30, 203.e1-203.e9
1.63Citations (PDF)
3Safety, efficacy and determinants of response of allogeneic CD19-specific CAR-NK cells in CD19+ B cell tumors: a phase 1/2 trial
Nature Medicine, 2024, 30, 772-784
25.6110Citations (PDF)
4Estrogen Receptor Mutations as Novel Targets for Immunotherapy in Metastatic Estrogen Receptor–positive Breast Cancer3.03Citations (PDF)
5Label-aware distance mitigates temporal and spatial variability for clustering and visualization of single-cell gene expression data4.51Citations (PDF)
6Forecasting acute kidney injury and resource utilization in ICU patients using longitudinal, multimodal models4.81Citations (PDF)
7CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis
Cancer Discovery, 2024, 14, 1879-1900
26.46Citations (PDF)
8Phase II study of talazoparib in advanced cancers with BRCA1/2, DNA repair, and PTEN alterations6.92Citations (PDF)
9BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML13.10Citations (PDF)
10Targeting the Epidermal Growth Factor Receptor Pathway in Chemotherapy-Resistant Triple-Negative Breast Cancer: A Phase II Study
Cancer Research Communications, 2024, 4, 2823-2834
3.03Citations (PDF)
11A spatially resolved single-cell genomic atlas of the adult human breast
Nature, 2023, 620, 181-191
40.166Citations (PDF)
12Integrative Prognostic Machine Learning Models in Mantle Cell Lymphoma
Cancer Research Communications, 2023, 3, 1435-1446
3.01Citations (PDF)
13Actionability classification of variants of unknown significance correlates with functional effect6.94Citations (PDF)
14Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance4.56Citations (PDF)
15Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering
Science Advances, 2023, 9,
11.338Citations (PDF)
16Single-nucleotide variant calling in single-cell sequencing data with Monopogen
Nature Biotechnology, 2023, 42, 803-812
18.18Citations (PDF)
17Characterizing cancer metabolism from bulk and single-cell RNA-seq data using METAFlux14.125Citations (PDF)
18Pathway centric analysis for single-cell RNA-seq and spatial transcriptomics data with GSDensity14.13Citations (PDF)
19Sensei: how many samples to tell a change in cell type abundance?
BMC Bioinformatics, 2022, 23,
3.33Citations (PDF)
20Clinical and Molecular Characterization of<i>POLE</i>Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers2.153Citations (PDF)
21Blinatumomab maintenance after allogeneic hematopoietic cell transplantation for B-lineage acute lymphoblastic leukemia
Blood, 2022, 139, 1908-1919
1.048Citations (PDF)
22Spatially resolved transcriptomics of high-grade serous ovarian carcinoma
IScience, 2022, 25, 103923
3.836Citations (PDF)
23Spatial charting of single-cell transcriptomes in tissues
Nature Biotechnology, 2022, 40, 1190-1199
18.1102Citations (PDF)
24Molecular Correlates of Venous Thromboembolism (VTE) in Ovarian Cancer
Cancers, 2022, 14, 1496
4.015Citations (PDF)
25In-depth analysis of SARS-CoV-2–specific T cells reveals diverse differentiation hierarchies in vaccinated individuals
JCI Insight, 2022, 7,
5.514Citations (PDF)
26BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint Therapy Efficacy
Cancer Immunology Research, 2022, 10, 597-611
3.717Citations (PDF)
27Bi-order multimodal integration of single-cell data
Genome Biology, 2022, 23,
8.425Citations (PDF)
28Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution14.116Citations (PDF)
29Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer
Nature Genetics, 2022, 54, 1390-1405
16.3102Citations (PDF)
30A phase two study of high dose blinatumomab in Richter’s syndrome
Leukemia, 2022, 36, 2228-2232
8.119Citations (PDF)
31KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape
Nature Medicine, 2022, 28, 2133-2144
25.690Citations (PDF)
32Direct CD32 T-cell cytotoxicity: implications for breast cancer prognosis and treatment
Life Science Alliance, 2022, 5, e202201590
2.72Citations (PDF)
33Ab initio spillover compensation in mass cytometry data2.710Citations (PDF)
34Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells
Blood, 2021, 137, 624-636
1.0188Citations (PDF)
35Stratified Test Accurately Identifies Differentially Expressed Genes Under Batch Effects in Single-Cell Data3.74Citations (PDF)
36MEDALT: single-cell copy number lineage tracing enabling gene discovery
Genome Biology, 2021, 22,
8.421Citations (PDF)
37Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia
IScience, 2021, 24, 102186
3.840Citations (PDF)
38Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer
Clinical Cancer Research, 2021, 27, 3243-3252
6.417Citations (PDF)
39Spatially interacting phosphorylation sites and mutations in cancer14.111Citations (PDF)
40Combining AFM13, a Bispecific CD30/CD16 Antibody, with Cytokine-Activated Blood and Cord Blood–Derived NK Cells Facilitates CAR-like Responses Against CD30+ Malignancies
Clinical Cancer Research, 2021, 27, 3744-3756
6.490Citations (PDF)
41Metabolic Reprogramming of GMP Grade Cord Tissue Derived Mesenchymal Stem Cells Enhances Their Suppressive Potential in GVHD5.015Citations (PDF)
42Single-cell manifold-preserving feature selection for detecting rare cell populations7.324Citations (PDF)
43Extended live-cell barcoding approach for multiplexed mass cytometry
Scientific Reports, 2021, 11,
3.711Citations (PDF)
44Uncoupling of gene expression from copy number presents therapeutic opportunities in aneuploid cancers
Cell Reports Medicine, 2021, 2, 100349
7.35Citations (PDF)
45Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells9.1147Citations (PDF)
46Generation of glucocorticoid-resistant SARS-CoV-2 T cells for adoptive cell therapy
Cell Reports, 2021, 36, 109432
6.426Citations (PDF)
47Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes2.79Citations (PDF)
48Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer
Cancer Research, 2021, 81, 5572-5581
0.682Citations (PDF)
49Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes
Nature Biotechnology, 2021, 39, 599-608
18.1353Citations (PDF)
50Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma
Nature Medicine, 2021, 27, 141-151
25.6150Citations (PDF)
51Targeting Polo-like Kinase 4 Triggers Polyploidy and Apoptotic Cell Death in TP53-Mutant Acute Myeloid Leukemia
Blood, 2021, 138, 1167-1167
1.04Citations (PDF)
52A robust benchmark for detection of germline large deletions and insertions
Nature Biotechnology, 2020, 38, 1347-1355
18.1198Citations (PDF)
53Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal Tract
Genes, 2020, 11, 645
2.756Citations (PDF)
54Latent periodic process inference from single-cell RNA-seq data14.118Citations (PDF)
55Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition
Nature Genetics, 2020, 52, 306-319
16.3257Citations (PDF)
56Stratified Test Alleviates Batch Effects in Single-Cell Data0.01Citations (PDF)
57Hybrid oncocytic/chromophobe renal tumors are molecularly distinct from oncocytoma and chromophobe renal cell carcinoma
Modern Pathology, 2019, 32, 1698-1707
5.037Citations (PDF)
58SiCloneFit: Bayesian inference of population structure, genotype, and phylogeny of tumor clones from single-cell genome sequencing data
Genome Research, 2019, 29, 1847-1859
4.671Citations (PDF)
59Elevated Endogenous SDHA Drives Pathological Metabolism in Highly Metastatic Uveal Melanoma
2019, 60, 4187
28Citations (PDF)
60SCMarker: Ab initio marker selection for single cell transcriptome profiling
PLoS Computational Biology, 2019, 15, e1007445
3.324Citations (PDF)
61Comments on the model parameters in “SiFit: inferring tumor trees from single-cell sequencing data under finite-sites models”
Genome Biology, 2019, 20,
8.40Citations (PDF)
62Multi-platform discovery of haplotype-resolved structural variation in human genomes14.1544Citations (PDF)
63Comparison of different functional prediction scores using a gene-based permutation model for identifying cancer driver genes1.87Citations (PDF)
64Integrated transcriptomic–genomic tool Texomer profiles cancer tissues
Nature Methods, 2019, 16, 401-404
14.56Citations (PDF)
65Prospective Clinical Sequencing of Adult Glioma
Molecular Cancer Therapeutics, 2019, 18, 991-1000
1.714Citations (PDF)
66A novel immature natural killer cell subpopulation predicts relapse after cord blood transplantation
Blood Advances, 2019, 3, 4117-4130
5.325Citations (PDF)
67Expanded Analysis of Secondary Germline Findings From Matched Tumor/Normal Sequencing Identifies Additional Clinically Significant Mutations2.112Citations (PDF)
68Single-nuclei RNA-seq on human retinal tissue provides improved transcriptome profiling14.182Citations (PDF)
69Distinct Biological Types of Ocular Adnexal Sebaceous Carcinoma: HPV-Driven and Virus-Negative Tumors Arise through Nonoverlapping Molecular-Genetic Alterations
Clinical Cancer Research, 2019, 25, 1280-1290
6.444Citations (PDF)
70Untying the gordion knot of targeting MET in cancer
Cancer Treatment Reviews, 2018, 66, 95-103
10.119Citations (PDF)
71Computational approaches for inferring tumor evolution from single-cell genomic data1.920Citations (PDF)
72Survival Outcomes by <i>TP53</i> Mutation Status in Metastatic Breast Cancer2.148Citations (PDF)
73Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface
PLoS ONE, 2018, 13, e0207897
2.513Citations (PDF)
74Genetic biomarkers of sensitivity and resistance to venetoclax monotherapy in patients with relapsed acute myeloid leukemia6.3120Citations (PDF)
75Structural Variant Breakpoint Detection with novoBreak0.02Citations (PDF)
76In vivo screening identifies GATAD2B as a metastasis driver in KRAS-driven lung cancer14.134Citations (PDF)
77Metachronous Medulloblastoma in a Child With Successfully Treated Neuroblastoma: Case Report and Novel Findings of DNA Sequencing16.12Citations (PDF)
78Targeted next generation sequencing of well-differentiated/dedifferentiated liposarcoma reveals novel gene amplifications and mutations
Oncotarget, 2018, 9, 19891-19899
1.727Citations (PDF)
79HySA: a Hybrid Structural variant Assembly approach using next-generation and single-molecule sequencing technologies
Genome Research, 2017, 27, 793-800
4.622Citations (PDF)
80Active Disclosure of Secondary Germline Findings to Deceased Research Participants’ Personal Representatives: Process and Outcomes2.14Citations (PDF)
81A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory
Oncotarget, 2017, 8, 41806-41814
1.713Citations (PDF)
82Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms14.167Citations (PDF)
83Ploidy-Seq: inferring mutational chronology by sequencing polyploid tumor subpopulations
Genome Medicine, 2015, 7,
9.96Citations (PDF)
84A Decision Support Framework for Genomically Informed Investigational Cancer Therapy5.1162Citations (PDF)
85Towards accurate characterization of clonal heterogeneity based on structural variation
BMC Bioinformatics, 2014, 15,
3.39Citations (PDF)
86A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival
Genes and Development, 2013, 27, 1462-1472
4.862Citations (PDF)
87Background Mutations in Parental Cells Account for Most of the Genetic Heterogeneity of Induced Pluripotent Stem Cells
Cell Stem Cell, 2012, 10, 570-582
17.2175Citations (PDF)
88Clonal Architecture of Secondary Acute Myeloid Leukemia
New England Journal of Medicine, 2012, 366, 1090-1098
25.5662Citations (PDF)
89Use of Whole-Genome Sequencing to Diagnose a Cryptic Fusion Oncogene13.7210Citations (PDF)
90Sequencing a mouse acute promyelocytic leukemia genome reveals genetic events relevant for disease progression
Journal of Clinical Investigation, 2011, 121, 1445-1455
9.183Citations (PDF)
91CMDS: a population-based method for identifying recurrent DNA copy number aberrations in cancer from high-resolution data
Bioinformatics, 2010, 26, 464-469
5.052Citations (PDF)
92PolyScan: An automatic indel and SNP detection approach to the analysis of human resequencing data
Genome Research, 2007, 17, 659-666
4.665Citations (PDF)
93An automatic prosody labeling system using ANN-based syntactic-prosodic model and GMM-based acoustic-prosodic model
0, ,
40Citations (PDF)
94Computational Prediction of Genetic Drivers in Cancer
0, , 1-16
3Citations (PDF)